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HUP0104416A2 - Use of n-substituted azabicycloalkane derivatives for treating diseases of the central nervous system and medicaments containing the compounds - Google Patents

Use of n-substituted azabicycloalkane derivatives for treating diseases of the central nervous system and medicaments containing the compounds

Info

Publication number
HUP0104416A2
HUP0104416A2 HU0104416A HUP0104416A HUP0104416A2 HU P0104416 A2 HUP0104416 A2 HU P0104416A2 HU 0104416 A HU0104416 A HU 0104416A HU P0104416 A HUP0104416 A HU P0104416A HU P0104416 A2 HUP0104416 A2 HU P0104416A2
Authority
HU
Hungary
Prior art keywords
compounds
nervous system
central nervous
treating diseases
medicaments containing
Prior art date
Application number
HU0104416A
Other languages
Hungarian (hu)
Inventor
Gerhard Gross
Rainer Munschauer
Gerd Steiner
Hans-Jürgen Teschendorf
Martin Traut
Liliane Unger
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of HUP0104416A2 publication Critical patent/HUP0104416A2/en
Publication of HUP0104416A3 publication Critical patent/HUP0104416A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Indole Compounds (AREA)

Abstract

A tal lm ny t rgya az ltal nos képletű N-szubsztitu lt 3-aza-bicikloalk n-sz rmazékok - ahol B adott esetben egy kettősk"tésttartalmazó 4-, 5- vagy 6-tagú gyűrű; R1 adott esetben szubsztitu ltfenil-, naftil-, fenantril- vagy tienilcsoport, R2 adott esetbenszubsztitu lt naftilcsoport vagy valamilyen "sszetett csoport; és n =0, 1, 2, 3 vagy 4 alkalmaz sa a hozz szok si rendellenességekvisszaszorít s ra és a k"zponti idegrendszer egyéb rendellenességeinekkezelésére és a vegyületeket tartalmazó gyógyszerkészítményekrevonatkozik. ÓThe material of this invention is the N-substituted 3-aza-bicycloalkane derivatives of the general formula - where B is optionally a double-membered 4-, 5- or 6-membered ring; R1 is optionally substituted phenyl-, naphthyl, phenanthryl or thienyl group, R2 optionally substituted naphthyl group or some "group" group; and n = 0, 1, 2, 3 or 4 are used for suppression of addiction disorders and for the treatment of other central nervous system disorders and pharmaceutical preparations containing the compounds.

HU0104416A 1998-11-24 1999-11-12 Use of n-substituted azabicycloalkane derivatives for treating diseases of the central nervous system and medicaments containing the compounds HUP0104416A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19854147A DE19854147A1 (en) 1998-11-24 1998-11-24 Control of cocaine addiction comprises administration of N-substituted azabicycloalkane derivative
PCT/EP1999/008734 WO2000030639A1 (en) 1998-11-24 1999-11-12 Use of n-substituted azabicycloalkane derivatives for treating diseases of the central nervous system

Publications (2)

Publication Number Publication Date
HUP0104416A2 true HUP0104416A2 (en) 2002-04-29
HUP0104416A3 HUP0104416A3 (en) 2002-11-28

Family

ID=7888824

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0104416A HUP0104416A3 (en) 1998-11-24 1999-11-12 Use of n-substituted azabicycloalkane derivatives for treating diseases of the central nervous system and medicaments containing the compounds

Country Status (21)

Country Link
EP (1) EP1133293A1 (en)
JP (1) JP2002530333A (en)
KR (1) KR20010080535A (en)
CN (1) CN1328455A (en)
AR (1) AR021502A1 (en)
AU (1) AU1775300A (en)
BG (1) BG105549A (en)
BR (1) BR9915589A (en)
CA (1) CA2352526A1 (en)
CZ (1) CZ20011796A3 (en)
DE (1) DE19854147A1 (en)
HK (1) HK1040933A1 (en)
HR (1) HRP20010472A2 (en)
HU (1) HUP0104416A3 (en)
IL (1) IL143181A0 (en)
NO (1) NO20012538L (en)
PL (1) PL348758A1 (en)
SK (1) SK7112001A3 (en)
TR (1) TR200101476T2 (en)
WO (1) WO2000030639A1 (en)
ZA (1) ZA200103976B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0519013A2 (en) 2004-12-13 2009-11-03 Lilly Co Eli single compound or stereoisomers, mixtures of pharmaceutically acceptable stereoisomers, salts, tautomers or prodrugs thereof, pharmaceutical composition, and use of a compound
GB0812310D0 (en) 2008-07-03 2008-08-13 Syngenta Ltd Novel herbicides
MX379289B (en) * 2013-01-15 2025-03-10 Novartis Ag USE OF ALPHA 7 NICOTINIC ACETYLCHOLINE RECEPTOR AGONISTS.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2717288A (en) * 1987-11-12 1989-06-01 American Home Products Corporation Polycyclicamines with psychotropic activity
DE4427648A1 (en) * 1994-08-04 1996-02-08 Basf Ag N-Stubstituted 3-azabicyclo [3,2,0,] heptane derivatives, their preparation and use
DE4341403A1 (en) * 1993-12-04 1995-06-08 Basf Ag N-substituted 3-azabicycloalkane derivatives, their preparation and use
DE4427647A1 (en) * 1994-08-04 1996-02-08 Basf Ag N-substituted azabicycloheptane derivatives, their preparation and use

Also Published As

Publication number Publication date
DE19854147A1 (en) 2000-05-25
HUP0104416A3 (en) 2002-11-28
BG105549A (en) 2001-12-29
IL143181A0 (en) 2002-04-21
CA2352526A1 (en) 2000-06-02
CZ20011796A3 (en) 2002-05-15
WO2000030639A1 (en) 2000-06-02
HRP20010472A2 (en) 2003-04-30
EP1133293A1 (en) 2001-09-19
AR021502A1 (en) 2002-07-24
NO20012538D0 (en) 2001-05-23
BR9915589A (en) 2001-08-07
CN1328455A (en) 2001-12-26
ZA200103976B (en) 2002-05-16
JP2002530333A (en) 2002-09-17
NO20012538L (en) 2001-07-04
TR200101476T2 (en) 2001-10-22
PL348758A1 (en) 2002-06-03
SK7112001A3 (en) 2001-12-03
HK1040933A1 (en) 2002-06-28
AU1775300A (en) 2000-06-13
KR20010080535A (en) 2001-08-22

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