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HUP0002935A2 - Gyomorban visszatartott, szabályozott hatóanyag kibocsátású mikrogömböcskék javított gyógyszeradagolás elősegítésére - Google Patents

Gyomorban visszatartott, szabályozott hatóanyag kibocsátású mikrogömböcskék javított gyógyszeradagolás elősegítésére

Info

Publication number
HUP0002935A2
HUP0002935A2 HU0002935A HUP0002935A HUP0002935A2 HU P0002935 A2 HUP0002935 A2 HU P0002935A2 HU 0002935 A HU0002935 A HU 0002935A HU P0002935 A HUP0002935 A HU P0002935A HU P0002935 A2 HUP0002935 A2 HU P0002935A2
Authority
HU
Hungary
Prior art keywords
drug delivery
controlled release
microspheres
improved drug
release microspheres
Prior art date
Application number
HU0002935A
Other languages
English (en)
Inventor
Lisbeth Illum
He Ping
Original Assignee
West Pharmaceutical Services Drug Delivery & Clinical Research Centre Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by West Pharmaceutical Services Drug Delivery & Clinical Research Centre Limited filed Critical West Pharmaceutical Services Drug Delivery & Clinical Research Centre Limited
Publication of HUP0002935A2 publication Critical patent/HUP0002935A2/hu
Publication of HUP0002935A3 publication Critical patent/HUP0002935A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A találmány gyógyszeradagoló összetételt nyújt valamely aktívalkotórész szabályozott kibocsátásához a gyomor környezetébenmegnyújtott időtartamon át, amely kompozíció mikrogömböcskékből áll,ahol a mikrogömböcskék állnak egy aktív alkotórészből amikrogömböcskék belső magjában, továbbá (i) egy vízben oldhatatlanpolimer sebességszabályozó rétegéből és (ii) egy kationos polimerformájában lévő, biológiailag tapadó szer külső rétegéből. Ó
HU00029350002935A 1997-05-24 1998-05-22 Gastroretentive controlled release microspheres fogastroretentive controlled release microspheres for improved drug delivery r improved drug delivery HUP0002935A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9710699.1A GB9710699D0 (en) 1997-05-24 1997-05-24 Gastro-retentive controlled release system

Publications (2)

Publication Number Publication Date
HUP0002935A2 true HUP0002935A2 (hu) 2000-12-28
HUP0002935A3 HUP0002935A3 (en) 2001-04-28

Family

ID=10812970

Family Applications (1)

Application Number Title Priority Date Filing Date
HU00029350002935A HUP0002935A3 (en) 1997-05-24 1998-05-22 Gastroretentive controlled release microspheres fogastroretentive controlled release microspheres for improved drug delivery r improved drug delivery

Country Status (22)

Country Link
US (1) US6207197B1 (hu)
EP (1) EP0984774B1 (hu)
JP (1) JP2001525848A (hu)
KR (1) KR20010012857A (hu)
CN (1) CN1257425A (hu)
AR (1) AR012854A1 (hu)
AT (1) ATE270880T1 (hu)
AU (1) AU737818B2 (hu)
BR (1) BR9809453A (hu)
CA (1) CA2285580A1 (hu)
DE (1) DE69825049T2 (hu)
ES (1) ES2226137T3 (hu)
GB (2) GB9710699D0 (hu)
HU (1) HUP0002935A3 (hu)
IL (1) IL132453A0 (hu)
NO (1) NO995753L (hu)
NZ (1) NZ338105A (hu)
PL (1) PL336037A1 (hu)
PT (1) PT984774E (hu)
SK (1) SK148999A3 (hu)
WO (1) WO1998052547A1 (hu)
ZA (1) ZA984379B (hu)

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DE69825049T2 (de) 2005-07-21
ZA984379B (en) 1999-11-22
HUP0002935A3 (en) 2001-04-28
GB9926405D0 (en) 2000-01-12
BR9809453A (pt) 2000-06-20
US6207197B1 (en) 2001-03-27
AU737818B2 (en) 2001-08-30
NO995753D0 (no) 1999-11-24
NO995753L (no) 1999-11-24
ATE270880T1 (de) 2004-07-15
DE69825049D1 (de) 2004-08-19
IL132453A0 (en) 2001-03-19
CA2285580A1 (en) 1998-11-26
CN1257425A (zh) 2000-06-21
KR20010012857A (ko) 2001-02-26
PT984774E (pt) 2004-11-30
GB9710699D0 (en) 1997-07-16
ES2226137T3 (es) 2005-03-16
GB2341550B (en) 2002-01-09
AU7664298A (en) 1998-12-11
AR012854A1 (es) 2000-11-22
GB2341550A (en) 2000-03-22
JP2001525848A (ja) 2001-12-11
EP0984774B1 (en) 2004-07-14
PL336037A1 (en) 2000-06-05
EP0984774A1 (en) 2000-03-15
WO1998052547A1 (en) 1998-11-26
SK148999A3 (en) 2000-07-11
NZ338105A (en) 2001-04-27

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