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HUP0001069A2 - Eljárás intravénás adagolásra alkalmas IgM-készítmény előállítására - Google Patents

Eljárás intravénás adagolásra alkalmas IgM-készítmény előállítására

Info

Publication number
HUP0001069A2
HUP0001069A2 HU0001069A HUP0001069A HUP0001069A2 HU P0001069 A2 HUP0001069 A2 HU P0001069A2 HU 0001069 A HU0001069 A HU 0001069A HU P0001069 A HUP0001069 A HU P0001069A HU P0001069 A2 HUP0001069 A2 HU P0001069A2
Authority
HU
Hungary
Prior art keywords
producing
igm
intravenous administration
igm preparation
preparation
Prior art date
Application number
HU0001069A
Other languages
English (en)
Inventor
Markus Rentsch
Original Assignee
Rotkreuzstiftung Zentrallaboratorium Blutspendedienst Srk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rotkreuzstiftung Zentrallaboratorium Blutspendedienst Srk filed Critical Rotkreuzstiftung Zentrallaboratorium Blutspendedienst Srk
Publication of HUP0001069A2 publication Critical patent/HUP0001069A2/hu
Publication of HUP0001069A3 publication Critical patent/HUP0001069A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A találmány tárgya eljárás intravénásan adagolható poliklonális,kémiailag nem módosított immunoglobulin készítmény előállítására,amely az összglobulinra vonatkoztatva több mint 5 tömeg% IgM-ttartalmaz, és alacsony antikomplementer aktivitást mutat. A találmányjellemző vonása, hogy a megfelelő IgM-tartalmú plazmafrakció vizesoldatát vagy szuszpenzióját proteázzal kezelik. Ó
HU0001069A 1996-10-14 1997-10-14 Method for producing an igm preparation for intravenous administration HUP0001069A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP96810690A EP0835880A1 (de) 1996-10-14 1996-10-14 Verfahren zur Herstellung eines IgM Präparates für die intravenöse Applikation
PCT/CH1997/000388 WO1998016558A1 (de) 1996-10-14 1997-10-14 VERFAHREN ZUR HERSTELLUNG EINES IgM-PRÄPARATES FÜR DIE INTRAVENÖSE APPLIKATION

Publications (2)

Publication Number Publication Date
HUP0001069A2 true HUP0001069A2 (hu) 2000-10-28
HUP0001069A3 HUP0001069A3 (en) 2000-12-28

Family

ID=8225725

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0001069A HUP0001069A3 (en) 1996-10-14 1997-10-14 Method for producing an igm preparation for intravenous administration

Country Status (19)

Country Link
US (1) US6136312A (hu)
EP (1) EP0835880A1 (hu)
JP (1) JP2001504092A (hu)
KR (1) KR20000048826A (hu)
CN (1) CN1233258A (hu)
AU (1) AU725134B2 (hu)
BR (1) BR9712306A (hu)
CA (1) CA2266848A1 (hu)
CZ (1) CZ125599A3 (hu)
HU (1) HUP0001069A3 (hu)
ID (1) ID21364A (hu)
IL (1) IL129383A0 (hu)
NO (1) NO991733L (hu)
NZ (1) NZ334885A (hu)
PL (1) PL332774A1 (hu)
RU (1) RU2191032C2 (hu)
SI (1) SI9720063A (hu)
SK (1) SK46699A3 (hu)
WO (1) WO1998016558A1 (hu)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8142780B2 (en) * 1998-08-20 2012-03-27 Strox Biopharmaceuticals, Llc Anti-bacterial antibodies
ATE490787T1 (de) * 2003-07-15 2010-12-15 Chugai Pharmaceutical Co Ltd Produktion von igm durch transformierte zellen und verfahren zur quantifizierung dieser igm- produktion
EP1688432B1 (en) * 2003-10-09 2011-08-03 Chugai Seiyaku Kabushiki Kaisha Igm high concentration stabilized solution
US7803914B2 (en) 2003-10-09 2010-09-28 Chugai Seiyaku Kabushiki Kaisha Methods for stabilizing protein solutions
ES2409844T3 (es) * 2006-01-30 2013-06-28 Grifols Therapeutics Inc. Metodo para el tratamiento y la profilaxis de enfermedades relacionadas con la deposicion de amiloide utilizando IgM
FR2899111B1 (fr) * 2006-03-31 2010-09-03 Lab Francais Du Fractionnement Concentre d'immunoglobulines specifiques du chikungunya en tant que medicament.
EP2291196A4 (en) * 2008-05-12 2012-05-30 Strox Biopharmaceuticals Llc FOR STAPHYLOCOCCUS AUREUS SPECIFIC ANTIBODY PREPARATIONS
CN101721633B (zh) * 2008-10-16 2011-12-21 岳道友 一种促进动物生长的中草药
GB201006753D0 (en) * 2010-04-22 2010-06-09 Biotest Ag Process for preparing an immunolobulin composition
RU2470664C2 (ru) * 2010-08-23 2012-12-27 Андрей Германович Лютов Способ получения иммуноглобулина для внутривенного введения, обогащенного иммуноглобулином м, и препарат, полученный этим способом
NZ726911A (en) 2014-06-03 2023-01-27 Xbiotech Inc Compositions and methods for treating and preventing staphylococcus aureus infections
CA3183021A1 (en) * 2020-07-10 2022-01-13 Myles Lindsay Method for obtaining a composition comprising human plasma-derived immunoglobulin m

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4075193A (en) * 1976-11-26 1978-02-21 Parke, Davis & Company Process for producing intravenous immune globulin
DE2901822A1 (de) * 1979-01-18 1980-07-31 Biotest Serum Institut Gmbh Verfahren zur herstellung einer fuer die intravenoese applikation geeigneten immunglobulinloesung, die igm in ankonzentrierter form enthaelt
AT383739B (de) * 1983-03-16 1987-08-10 Immuno Ag Verfahren zur inaktivierung von unvertraeglichkeitsreaktionen verursachenden substanzen in immunglobulinhaeltigen blutfraktionen
IT1186766B (it) * 1985-11-08 1987-12-16 Sclavo Spa Metodo per la preparazione di immunoglobuline per uso endovenoso
DE3825429C2 (de) * 1988-07-27 1994-02-10 Biotest Pharma Gmbh Verfahren zur Herstellung eines intravenös verabreichbaren polyklonalen Immunglobulin-Präparates mit hohem IgM-Gehalt
DE3927112C1 (hu) * 1989-08-17 1990-10-25 Biotest Pharma Gmbh, 6072 Dreieich, De
DE3927111C3 (de) * 1989-08-17 1994-09-01 Biotest Pharma Gmbh Verfahren zur Herstellung nicht modifizierter intravenös verabreichbarer IgM- und/oderIgA-haltiger Immunglobulinpräparate

Also Published As

Publication number Publication date
EP0835880A1 (de) 1998-04-15
CZ125599A3 (cs) 1999-07-14
WO1998016558A1 (de) 1998-04-23
SI9720063A (sl) 1999-08-31
RU2191032C2 (ru) 2002-10-20
AU725134B2 (en) 2000-10-05
AU4449597A (en) 1998-05-11
PL332774A1 (en) 1999-10-11
KR20000048826A (ko) 2000-07-25
CA2266848A1 (en) 1998-04-23
NO991733D0 (no) 1999-04-13
IL129383A0 (en) 2000-02-17
NZ334885A (en) 2000-09-29
ID21364A (id) 1999-05-27
US6136312A (en) 2000-10-24
JP2001504092A (ja) 2001-03-27
HUP0001069A3 (en) 2000-12-28
CN1233258A (zh) 1999-10-27
NO991733L (no) 1999-06-11
BR9712306A (pt) 1999-08-31
SK46699A3 (en) 2000-06-12

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