HUE065712T2 - Kardiálisszarkomer inhibitor orális készítmények - Google Patents
Kardiálisszarkomer inhibitor orális készítményekInfo
- Publication number
- HUE065712T2 HUE065712T2 HUE20753563A HUE20753563A HUE065712T2 HU E065712 T2 HUE065712 T2 HU E065712T2 HU E20753563 A HUE20753563 A HU E20753563A HU E20753563 A HUE20753563 A HU E20753563A HU E065712 T2 HUE065712 T2 HU E065712T2
- Authority
- HU
- Hungary
- Prior art keywords
- oral formulations
- cardiac sarcomere
- inhibitor oral
- inhibitor
- sarcomere
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hospice & Palliative Care (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962875358P | 2019-07-17 | 2019-07-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE065712T2 true HUE065712T2 (hu) | 2024-06-28 |
Family
ID=71995104
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE20753563A HUE065712T2 (hu) | 2019-07-17 | 2020-07-16 | Kardiálisszarkomer inhibitor orális készítmények |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US20220265612A1 (hu) |
| EP (1) | EP3999038B1 (hu) |
| JP (1) | JP7623342B2 (hu) |
| KR (1) | KR20220082804A (hu) |
| CN (1) | CN114765954B (hu) |
| AU (1) | AU2020315642A1 (hu) |
| BR (1) | BR112022000495A2 (hu) |
| CA (1) | CA3144972A1 (hu) |
| CL (1) | CL2022000108A1 (hu) |
| DK (1) | DK3999038T3 (hu) |
| ES (1) | ES2974542T3 (hu) |
| FI (1) | FI3999038T3 (hu) |
| HR (1) | HRP20240200T1 (hu) |
| HU (1) | HUE065712T2 (hu) |
| IL (1) | IL289884A (hu) |
| LT (1) | LT3999038T (hu) |
| MX (1) | MX2022000708A (hu) |
| PH (1) | PH12022550083A1 (hu) |
| PL (1) | PL3999038T3 (hu) |
| PT (1) | PT3999038T (hu) |
| RS (1) | RS65302B1 (hu) |
| SI (1) | SI3999038T1 (hu) |
| SM (1) | SMT202400107T1 (hu) |
| TW (1) | TW202116307A (hu) |
| WO (1) | WO2021011808A1 (hu) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW202436291A (zh) | 2018-01-19 | 2024-09-16 | 美商胞質動力學公司 | 心肌節抑制劑 |
| WO2020005888A1 (en) | 2018-06-26 | 2020-01-02 | Cytokinetics, Inc. | Cardiac sarcomere inhibitors |
| WO2020005887A1 (en) | 2018-06-26 | 2020-01-02 | Cytokinetics, Inc. | Cardiac sarcomere inhibitors |
| TWI848972B (zh) | 2018-08-31 | 2024-07-21 | 美商胞質動力學公司 | 心臟肌小節抑制劑 |
| CN117083275A (zh) | 2021-03-04 | 2023-11-17 | 赛特凯恩蒂克公司 | 心脏肌节抑制剂 |
| CA3225787A1 (en) | 2021-07-16 | 2023-01-19 | Cytokinetics, Inc. | Methods for treating hypertrophic cardiomyopathy |
| TW202423423A (zh) | 2022-07-20 | 2024-06-16 | 美商胞質動力學公司 | 治療非阻塞性肥厚性心肌病之方法 |
| AU2023320493A1 (en) | 2022-08-04 | 2025-01-30 | Cytokinetics, Incorporated | Methods for treating obstructive hypertrophic cardiomyopathy |
| WO2024179422A1 (zh) * | 2023-03-02 | 2024-09-06 | 苏州科睿思制药有限公司 | Aficamten的共晶及其制备方法和用途 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1934228A2 (en) * | 2005-09-01 | 2008-06-25 | Array Biopharma, Inc. | Raf inhibitor compounds and methods of use thereof |
| SI2477611T1 (sl) * | 2009-09-18 | 2017-07-31 | Sanofi | Formulacije tablete (Z)-2-ciano-3-hidroksi-but-2-enojska kislina-(4'-trifluormetilfenil)-amida z izboljšano stabilnostjo |
| US9199945B2 (en) * | 2013-06-21 | 2015-12-01 | MyoKardia, Inc. | Cycloalkyl-substituted pyrimidinedione compounds |
| US9902702B2 (en) * | 2014-07-15 | 2018-02-27 | Bristol-Myers Squibb Company | Spirocycloheptanes as inhibitors of rock |
| CA3038280A1 (en) * | 2015-09-30 | 2017-04-06 | Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. - Generalverwaltung | Heteroaryl derivatives as sepiapterin reductase inhibitors |
| TW202436291A (zh) | 2018-01-19 | 2024-09-16 | 美商胞質動力學公司 | 心肌節抑制劑 |
-
2020
- 2020-07-16 KR KR1020227003543A patent/KR20220082804A/ko active Pending
- 2020-07-16 WO PCT/US2020/042389 patent/WO2021011808A1/en active Application Filing
- 2020-07-16 PH PH1/2022/550083A patent/PH12022550083A1/en unknown
- 2020-07-16 HU HUE20753563A patent/HUE065712T2/hu unknown
- 2020-07-16 JP JP2022502218A patent/JP7623342B2/ja active Active
- 2020-07-16 SI SI202030397T patent/SI3999038T1/sl unknown
- 2020-07-16 ES ES20753563T patent/ES2974542T3/es active Active
- 2020-07-16 DK DK20753563.4T patent/DK3999038T3/da active
- 2020-07-16 LT LTEPPCT/US2020/042389T patent/LT3999038T/lt unknown
- 2020-07-16 AU AU2020315642A patent/AU2020315642A1/en active Pending
- 2020-07-16 FI FIEP20753563.4T patent/FI3999038T3/fi active
- 2020-07-16 RS RS20240236A patent/RS65302B1/sr unknown
- 2020-07-16 CN CN202080062806.7A patent/CN114765954B/zh active Active
- 2020-07-16 PT PT207535634T patent/PT3999038T/pt unknown
- 2020-07-16 HR HRP20240200TT patent/HRP20240200T1/hr unknown
- 2020-07-16 TW TW109124113A patent/TW202116307A/zh unknown
- 2020-07-16 CA CA3144972A patent/CA3144972A1/en active Pending
- 2020-07-16 PL PL20753563.4T patent/PL3999038T3/pl unknown
- 2020-07-16 SM SM20240107T patent/SMT202400107T1/it unknown
- 2020-07-16 US US17/627,600 patent/US20220265612A1/en active Pending
- 2020-07-16 MX MX2022000708A patent/MX2022000708A/es unknown
- 2020-07-16 EP EP20753563.4A patent/EP3999038B1/en active Active
- 2020-07-16 BR BR112022000495A patent/BR112022000495A2/pt unknown
-
2022
- 2022-01-15 CL CL2022000108A patent/CL2022000108A1/es unknown
- 2022-01-16 IL IL289884A patent/IL289884A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TW202116307A (zh) | 2021-05-01 |
| HRP20240200T1 (hr) | 2024-04-26 |
| PL3999038T3 (pl) | 2024-05-13 |
| JP7623342B2 (ja) | 2025-01-28 |
| KR20220082804A (ko) | 2022-06-17 |
| WO2021011808A1 (en) | 2021-01-21 |
| AU2020315642A1 (en) | 2022-03-03 |
| CN114765954B (zh) | 2024-01-02 |
| MX2022000708A (es) | 2022-02-23 |
| PT3999038T (pt) | 2024-03-14 |
| IL289884A (en) | 2022-03-01 |
| CA3144972A1 (en) | 2021-01-21 |
| US20220265612A1 (en) | 2022-08-25 |
| SMT202400107T1 (it) | 2024-05-14 |
| FI3999038T3 (fi) | 2024-02-21 |
| EP3999038A1 (en) | 2022-05-25 |
| DK3999038T3 (da) | 2024-03-18 |
| JP2022542804A (ja) | 2022-10-07 |
| LT3999038T (lt) | 2024-03-25 |
| EP3999038B1 (en) | 2024-01-10 |
| SI3999038T1 (sl) | 2024-05-31 |
| CL2022000108A1 (es) | 2022-10-21 |
| ES2974542T3 (es) | 2024-06-27 |
| PH12022550083A1 (en) | 2023-04-12 |
| BR112022000495A2 (pt) | 2022-03-03 |
| CN114765954A (zh) | 2022-07-19 |
| RS65302B1 (sr) | 2024-04-30 |
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