HUE054626T2 - Eljárás D-arginil-2,6-dimetil-L-tirozil-L-lizil-L-fenilalaninamid elõállítására - Google Patents

Eljárás D-arginil-2,6-dimetil-L-tirozil-L-lizil-L-fenilalaninamid elõállítására

Info

Publication number: HUE054626T2
Authority: HU; Hungary
Prior art keywords: phenylalaninamide; tyrosyl; arginyl; lysyl; dimethyl
Prior art date: 2014-06-25

Application number

HUE15738001A

Other languages

English (en)

Inventor

Xinjun Zhao

Original Assignee

Flamma Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2014-06-25

Filing date

2015-06-24

Publication date

2021-09-28

2015-06-24 Application filed by Flamma Spa filed Critical Flamma Spa

2021-09-28 Publication of HUE054626T2 publication Critical patent/HUE054626T2/hu

Links

SFVLTCAESLKEHH-WKAQUBQDSA-N (2s)-6-amino-2-[[(2s)-2-[[(2r)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-n-[(2s)-1-amino-1-oxo-3-phenylpropan-2-yl]hexanamide Chemical compound CC1=CC(O)=CC(C)=C1C[C@H](NC(=O)[C@H](N)CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(N)=O)CC1=CC=CC=C1 SFVLTCAESLKEHH-WKAQUBQDSA-N 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1019—Tetrapeptides with the first amino acid being basic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06086—Dipeptides with the first amino acid being basic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Life Sciences & Earth Sciences (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

HUE15738001A 2014-06-25 2015-06-24 Eljárás D-arginil-2,6-dimetil-L-tirozil-L-lizil-L-fenilalaninamid elõállítására HUE054626T2 (hu)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US201462016783P	2014-06-25	2014-06-25

Publications (1)

Publication Number	Publication Date
HUE054626T2 true HUE054626T2 (hu)	2021-09-28

Family

ID=53546576

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HUE15738001A HUE054626T2 (hu)	2014-06-25	2015-06-24	Eljárás D-arginil-2,6-dimetil-L-tirozil-L-lizil-L-fenilalaninamid elõállítására

Country Status (8)

Country	Link
US (1)	US10125164B2 (hu)
EP (1)	EP3160984B1 (hu)
JP (1)	JP2017523956A (hu)
ES (1)	ES2869430T3 (hu)
HU (1)	HUE054626T2 (hu)
PL (1)	PL3160984T3 (hu)
SI (1)	SI3160984T1 (hu)
WO (1)	WO2015197723A1 (hu)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US9982014B2 (en) *	2013-10-23	2018-05-29	Kaneka Corporation	Tetrapeptide compound and method for producing same
EP3160985B1 (en) *	2014-06-30	2021-07-28	Flamma S.P.A.	Process for the production of d-arginyl-2,6-dimethyl-l-tyrosyl-l-lysyl-l-phenylalaninamide
US11795196B2 (en)	2017-12-15	2023-10-24	Stealth Biotherapeutics Inc.	Mitochondria-targeting peptides
ES2942631T3 (es)	2017-12-15	2023-06-05	Stealth Biotherapeutics Inc	Péptidos dirigidos a mitocondrias
US20230227499A1 (en) *	2020-06-22	2023-07-20	Stealth Biotherapeutics Inc.	Prodrugs of mitochondria-targeting oligopeptides

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1184317B (it) *	1985-02-05	1987-10-28	Eniricerche Spa	Retro-inverso analoghi del peptide potenziatore della bradichina bpp5a
SE9900961D0 (sv)	1999-03-16	1999-03-16	Astra Ab	Novel compounds
ES2540897T3 (es)	2003-02-04	2015-07-14	Cornell Research Foundation, Inc.	Usos de péptidos catiónicos aromáticos
DK1625149T3 (en)	2003-05-01	2016-05-30	Cornell Res Foundation Inc	METHOD AND carrying complexes for delivery of molecules to cells
CN1938042B (zh)	2004-01-23	2010-06-02	科内尔研究基金会	芳香族阳离子肽在制备用于减轻氧化性损伤药物中的应用
WO2007027742A2 (en) *	2005-08-31	2007-03-08	The Trustees Of The University Of Pennsylvania	SMALL MOLECULE INTEGRIN α2βl/GPIa-IIa ANTAGONISTS
US8716439B2 (en) *	2006-03-01	2014-05-06	Kaneka Corporation	Method of producing peptide
CN107802821A (zh)	2008-02-26	2018-03-16	康奈尔大学	用于防止和治疗急性肾损伤的方法
US20110245183A1 (en)	2010-04-06	2011-10-06	Perricone Nicholas V	Topical Uses of Szeto-Schiller Peptides
US20110245182A1 (en)	2010-04-06	2011-10-06	Perricone Nicholas V	Topical Uses of Szeto-Schiller Peptides
US20120083452A1 (en)	2010-09-30	2012-04-05	Perricone Nicholas V	Topical Anesthetic Uses of Szeto-Schiller Peptides
JP2014518213A (ja)	2011-06-14	2014-07-28	ステルスペプチドズインターナショナルインコーポレイテッド	芳香族カチオン性ペプチド及びその使用
CA2858550A1 (en)	2011-12-09	2013-06-13	Stealth Peptides International, Inc.	Aromatic-cationic peptides and uses of same
WO2014210056A1 (en)	2013-06-27	2014-12-31	Stealth Peptides International, Inc.	Peptide therapeutics and methods for using same
US9982014B2 (en) *	2013-10-23	2018-05-29	Kaneka Corporation	Tetrapeptide compound and method for producing same
CN106132984B (zh) *	2013-12-27	2020-12-08	康德生物医疗技术公司	药学相关的芳香族阳离子肽
EP3160985B1 (en) *	2014-06-30	2021-07-28	Flamma S.P.A.	Process for the production of d-arginyl-2,6-dimethyl-l-tyrosyl-l-lysyl-l-phenylalaninamide

2015
- 2015-06-24 US US15/319,858 patent/US10125164B2/en active Active
- 2015-06-24 WO PCT/EP2015/064301 patent/WO2015197723A1/en active Application Filing
- 2015-06-24 EP EP15738001.5A patent/EP3160984B1/en active Active
- 2015-06-24 SI SI201531587T patent/SI3160984T1/sl unknown
- 2015-06-24 PL PL15738001T patent/PL3160984T3/pl unknown
- 2015-06-24 ES ES15738001T patent/ES2869430T3/es active Active
- 2015-06-24 JP JP2016574053A patent/JP2017523956A/ja active Pending
- 2015-06-24 HU HUE15738001A patent/HUE054626T2/hu unknown

Also Published As

Publication number	Publication date
ES2869430T3 (es)	2021-10-25
WO2015197723A1 (en)	2015-12-30
EP3160984B1 (en)	2021-04-14
EP3160984A1 (en)	2017-05-03
US10125164B2 (en)	2018-11-13
SI3160984T1 (sl)	2021-08-31
US20170129920A1 (en)	2017-05-11
JP2017523956A (ja)	2017-08-24
PL3160984T3 (pl)	2021-10-25

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