HUE053358T2 - 5-Metil-6-fenil-4,5-dihidro-2H-piridazin-3-on származék agytumorok kezelésére - Google Patents
5-Metil-6-fenil-4,5-dihidro-2H-piridazin-3-on származék agytumorok kezeléséreInfo
- Publication number
- HUE053358T2 HUE053358T2 HUE17711366A HUE17711366A HUE053358T2 HU E053358 T2 HUE053358 T2 HU E053358T2 HU E17711366 A HUE17711366 A HU E17711366A HU E17711366 A HUE17711366 A HU E17711366A HU E053358 T2 HUE053358 T2 HU E053358T2
- Authority
- HU
- Hungary
- Prior art keywords
- pyridazin
- dihydro
- phenyl
- derivative
- methyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/04—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/14—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2016042535 | 2016-03-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE053358T2 true HUE053358T2 (hu) | 2021-06-28 |
Family
ID=58347859
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE17711366A HUE053358T2 (hu) | 2016-03-04 | 2017-03-02 | 5-Metil-6-fenil-4,5-dihidro-2H-piridazin-3-on származék agytumorok kezelésére |
Country Status (29)
| Country | Link |
|---|---|
| US (4) | US10611731B2 (hu) |
| EP (1) | EP3423440B9 (hu) |
| JP (1) | JP6596595B2 (hu) |
| KR (1) | KR102350772B1 (hu) |
| CN (1) | CN108779076B (hu) |
| AU (2) | AU2017226674B2 (hu) |
| CA (1) | CA3015331A1 (hu) |
| CY (1) | CY1123927T1 (hu) |
| DK (1) | DK3423440T3 (hu) |
| EA (1) | EA036423B1 (hu) |
| ES (1) | ES2862177T3 (hu) |
| HR (1) | HRP20210395T1 (hu) |
| HU (1) | HUE053358T2 (hu) |
| IL (1) | IL261225B (hu) |
| LT (1) | LT3423440T (hu) |
| MX (1) | MX377854B (hu) |
| MY (1) | MY196801A (hu) |
| NZ (1) | NZ745688A (hu) |
| PH (1) | PH12018501873B1 (hu) |
| PL (1) | PL3423440T3 (hu) |
| PT (1) | PT3423440T (hu) |
| RS (1) | RS61593B1 (hu) |
| SA (1) | SA518392275B1 (hu) |
| SG (1) | SG11201807146SA (hu) |
| SI (1) | SI3423440T1 (hu) |
| SM (1) | SMT202100138T1 (hu) |
| TW (1) | TWI731041B (hu) |
| WO (1) | WO2017150654A1 (hu) |
| ZA (1) | ZA201805791B (hu) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7104588B2 (ja) * | 2017-09-01 | 2022-07-21 | 大塚製薬株式会社 | ５－メチル－６－フェニル－４，５－ジヒドロ－２ｈ－ピリダジン－３－オン誘導体を含有する悪性腫瘍治療剤 |
| WO2020157194A1 (en) * | 2019-02-01 | 2020-08-06 | Bayer Aktiengesellschaft | 1,2,4-triazin-3(2h)-one compounds for the treatment of hyperproliferative diseases |
| WO2024232361A1 (en) | 2023-05-08 | 2024-11-14 | Otsuka Pharmaceutical Co., Ltd. | Inhibitor of megakaryocyte differentiation and maturation |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63145272A (ja) * | 1986-12-09 | 1988-06-17 | Morishita Seiyaku Kk | ４，５−ジヒドロ−６−（４−置換フエニル）−３（２ｈ）−ピリダジノン誘導体 |
| US5100892A (en) * | 1990-11-13 | 1992-03-31 | Glaxo Inc. | Dihydropyridine vasodilator agents |
| US5563143A (en) * | 1994-09-21 | 1996-10-08 | Pfizer Inc. | Catechol diether compounds as inhibitors of TNF release |
| CA2205757C (en) * | 1996-05-30 | 2006-01-24 | F. Hoffmann-La Roche Ag | Pyridazinone derivatives and their use as inhibitors of prostaglandin g/h synthase i and ii(cox i and ii) |
| JP2008521806A (ja) * | 2004-11-30 | 2008-06-26 | アーテシアン セラピューティクス， インコーポレイテッド | 心不全を治療するための混合型のＰＤＥ−阻害活性およびβ−アドレナリン作用性アンタゴニスト活性または部分アゴニスト活性を有する化合物 |
| US20100160335A1 (en) | 2007-06-19 | 2010-06-24 | Kyorin Pharmaceutical Co., Ltd. | Pyridazinone derivative and pde inhibitor containing the same as active ingredient |
| CN101538245B (zh) | 2008-03-18 | 2011-02-16 | 中国科学院上海药物研究所 | 一类哒嗪酮类化合物及其制备方法和制备药物的用途 |
| WO2014164704A2 (en) * | 2013-03-11 | 2014-10-09 | The Broad Institute, Inc. | Compounds and compositions for the treatment of cancer |
-
2017
- 2017-03-02 KR KR1020187028010A patent/KR102350772B1/ko active Active
- 2017-03-02 PH PH1/2018/501873A patent/PH12018501873B1/en unknown
- 2017-03-02 MY MYPI2018703021A patent/MY196801A/en unknown
- 2017-03-02 AU AU2017226674A patent/AU2017226674B2/en active Active
- 2017-03-02 EP EP17711366.9A patent/EP3423440B9/en active Active
- 2017-03-02 NZ NZ745688A patent/NZ745688A/en unknown
- 2017-03-02 ES ES17711366T patent/ES2862177T3/es active Active
- 2017-03-02 JP JP2018544577A patent/JP6596595B2/ja active Active
- 2017-03-02 TW TW106106813A patent/TWI731041B/zh active
- 2017-03-02 SI SI201730668T patent/SI3423440T1/sl unknown
- 2017-03-02 CA CA3015331A patent/CA3015331A1/en active Pending
- 2017-03-02 RS RS20210193A patent/RS61593B1/sr unknown
- 2017-03-02 SM SM20210138T patent/SMT202100138T1/it unknown
- 2017-03-02 CN CN201780013870.4A patent/CN108779076B/zh active Active
- 2017-03-02 EA EA201891987A patent/EA036423B1/ru not_active IP Right Cessation
- 2017-03-02 MX MX2018010535A patent/MX377854B/es unknown
- 2017-03-02 WO PCT/JP2017/008246 patent/WO2017150654A1/en active Application Filing
- 2017-03-02 SG SG11201807146SA patent/SG11201807146SA/en unknown
- 2017-03-02 DK DK17711366.9T patent/DK3423440T3/da active
- 2017-03-02 PT PT177113669T patent/PT3423440T/pt unknown
- 2017-03-02 PL PL17711366T patent/PL3423440T3/pl unknown
- 2017-03-02 LT LTEP17711366.9T patent/LT3423440T/lt unknown
- 2017-03-02 HU HUE17711366A patent/HUE053358T2/hu unknown
- 2017-03-02 US US16/081,260 patent/US10611731B2/en active Active
-
2018
- 2018-08-19 IL IL261225A patent/IL261225B/en unknown
- 2018-08-26 SA SA518392275A patent/SA518392275B1/ar unknown
- 2018-08-29 ZA ZA2018/05791A patent/ZA201805791B/en unknown
-
2020
- 2020-02-12 US US16/788,894 patent/US20200181092A1/en not_active Abandoned
-
2021
- 2021-02-22 AU AU2021201135A patent/AU2021201135B2/en active Active
- 2021-02-23 US US17/182,549 patent/US20210171472A1/en not_active Abandoned
- 2021-02-24 CY CY20211100155T patent/CY1123927T1/el unknown
- 2021-03-08 HR HRP20210395TT patent/HRP20210395T1/hr unknown
-
2024
- 2024-08-08 US US18/798,284 patent/US20240400520A1/en active Pending
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