HUE050459T2 - Androgénreceptor-gátló kristályformája és annak elõállítási eljárása - Google Patents
Androgénreceptor-gátló kristályformája és annak elõállítási eljárásaInfo
- Publication number
- HUE050459T2 HUE050459T2 HUE16843560A HUE16843560A HUE050459T2 HU E050459 T2 HUE050459 T2 HU E050459T2 HU E16843560 A HUE16843560 A HU E16843560A HU E16843560 A HUE16843560 A HU E16843560A HU E050459 T2 HUE050459 T2 HU E050459T2
- Authority
- HU
- Hungary
- Prior art keywords
- preparation
- crystal form
- androgen receptor
- receptor inhibitor
- inhibitor crystal
- Prior art date
Links
- 102000001307 androgen receptors Human genes 0.000 title 1
- 108010080146 androgen receptors Proteins 0.000 title 1
- 239000013078 crystal Substances 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/86—Oxygen and sulfur atoms, e.g. thiohydantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4166—1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510574141 | 2015-09-10 | ||
| CN201610073458 | 2016-02-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE050459T2 true HUE050459T2 (hu) | 2020-12-28 |
Family
ID=58240573
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE16843560A HUE050459T2 (hu) | 2015-09-10 | 2016-08-23 | Androgénreceptor-gátló kristályformája és annak elõállítási eljárása |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US10150739B2 (hu) |
| EP (1) | EP3348546B1 (hu) |
| JP (1) | JP6843116B2 (hu) |
| KR (1) | KR20180048939A (hu) |
| CN (1) | CN107001284B (hu) |
| AU (1) | AU2016318700B2 (hu) |
| BR (1) | BR112018003258A2 (hu) |
| CA (1) | CA2996674A1 (hu) |
| CY (1) | CY1123027T1 (hu) |
| DK (1) | DK3348546T3 (hu) |
| ES (1) | ES2794568T3 (hu) |
| HR (1) | HRP20200852T1 (hu) |
| HU (1) | HUE050459T2 (hu) |
| LT (1) | LT3348546T (hu) |
| MX (1) | MX2018002759A (hu) |
| PL (1) | PL3348546T3 (hu) |
| PT (1) | PT3348546T (hu) |
| RS (1) | RS60448B1 (hu) |
| RU (1) | RU2018109121A (hu) |
| SI (1) | SI3348546T1 (hu) |
| SM (1) | SMT202000258T1 (hu) |
| TW (1) | TWI708764B (hu) |
| WO (1) | WO2017041622A1 (hu) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL3348546T3 (pl) | 2015-09-10 | 2020-09-21 | Jiangsu Hengrui Medicine Co., Ltd. | Krystaliczna forma inhibitora receptora androgenu i sposób przygotowania |
| CN109912509B (zh) * | 2017-12-13 | 2021-02-26 | 江苏恒瑞医药股份有限公司 | 一种雄性激素受体抑制剂的晶型及其制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200621723A (en) * | 2004-09-09 | 2006-07-01 | Chugai Pharmaceutical Co Ltd | Novel imidazolidine derivative and use thereof |
| KR101782236B1 (ko) | 2005-05-13 | 2017-09-26 | 더 리전트 오브 더 유니버시티 오브 캘리포니아 | 디아릴히단토인 화합물 |
| EP2416657A4 (en) * | 2009-04-09 | 2012-09-05 | Medivation Prostate Therapeutics Inc | COMPOUNDS COMPRISING SUBSTITUTED DI-ARYLHYDANTOIDS AND DI-ARYLTHIOHYDANTOINES AND METHODS OF USE THEREOF |
| AU2013312587B2 (en) * | 2012-09-04 | 2017-03-16 | Jiangsu Hengrui Medicine Co., Ltd. | Imidazoline derivatives, preparation methods thereof, and their applications in medicine |
| MX2015003124A (es) * | 2012-09-11 | 2015-10-12 | Reddys Lab Ltd Dr | Formas polimorficas de enzalutamida y su preparacion. |
| CN104356068A (zh) * | 2014-10-30 | 2015-02-18 | 杭州新博思生物医药有限公司 | 恩杂鲁胺新晶型及其制备方法 |
| PL3348546T3 (pl) | 2015-09-10 | 2020-09-21 | Jiangsu Hengrui Medicine Co., Ltd. | Krystaliczna forma inhibitora receptora androgenu i sposób przygotowania |
-
2016
- 2016-08-23 PL PL16843560T patent/PL3348546T3/pl unknown
- 2016-08-23 BR BR112018003258-1A patent/BR112018003258A2/pt not_active Application Discontinuation
- 2016-08-23 CA CA2996674A patent/CA2996674A1/en active Pending
- 2016-08-23 WO PCT/CN2016/096381 patent/WO2017041622A1/zh active Application Filing
- 2016-08-23 PT PT168435600T patent/PT3348546T/pt unknown
- 2016-08-23 SM SM20200258T patent/SMT202000258T1/it unknown
- 2016-08-23 SI SI201630801T patent/SI3348546T1/sl unknown
- 2016-08-23 JP JP2018508712A patent/JP6843116B2/ja not_active Expired - Fee Related
- 2016-08-23 US US15/757,652 patent/US10150739B2/en active Active
- 2016-08-23 ES ES16843560T patent/ES2794568T3/es active Active
- 2016-08-23 KR KR1020187009184A patent/KR20180048939A/ko not_active Application Discontinuation
- 2016-08-23 RU RU2018109121A patent/RU2018109121A/ru unknown
- 2016-08-23 RS RS20200617A patent/RS60448B1/sr unknown
- 2016-08-23 AU AU2016318700A patent/AU2016318700B2/en not_active Ceased
- 2016-08-23 CN CN201680003850.4A patent/CN107001284B/zh active Active
- 2016-08-23 LT LTEP16843560.0T patent/LT3348546T/lt unknown
- 2016-08-23 DK DK16843560.0T patent/DK3348546T3/da active
- 2016-08-23 EP EP16843560.0A patent/EP3348546B1/en active Active
- 2016-08-23 HU HUE16843560A patent/HUE050459T2/hu unknown
- 2016-08-23 MX MX2018002759A patent/MX2018002759A/es unknown
- 2016-09-07 TW TW105128891A patent/TWI708764B/zh not_active IP Right Cessation
-
2020
- 2020-05-26 HR HRP20200852TT patent/HRP20200852T1/hr unknown
- 2020-06-09 CY CY20201100522T patent/CY1123027T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR112018003258A2 (pt) | 2018-09-25 |
| AU2016318700A1 (en) | 2018-04-05 |
| AU2016318700B2 (en) | 2020-05-07 |
| KR20180048939A (ko) | 2018-05-10 |
| CN107001284A (zh) | 2017-08-01 |
| TW201713628A (zh) | 2017-04-16 |
| CY1123027T1 (el) | 2021-10-29 |
| JP2018526364A (ja) | 2018-09-13 |
| RU2018109121A3 (hu) | 2019-12-04 |
| TWI708764B (zh) | 2020-11-01 |
| RU2018109121A (ru) | 2019-10-10 |
| SMT202000258T1 (it) | 2020-07-08 |
| PT3348546T (pt) | 2020-05-29 |
| EP3348546A4 (en) | 2019-03-27 |
| US20180244628A1 (en) | 2018-08-30 |
| EP3348546B1 (en) | 2020-04-29 |
| PL3348546T3 (pl) | 2020-09-21 |
| ES2794568T3 (es) | 2020-11-18 |
| JP6843116B2 (ja) | 2021-03-17 |
| EP3348546A1 (en) | 2018-07-18 |
| LT3348546T (lt) | 2020-07-27 |
| SI3348546T1 (sl) | 2020-09-30 |
| CA2996674A1 (en) | 2017-03-16 |
| RS60448B1 (sr) | 2020-07-31 |
| CN107001284B (zh) | 2019-11-22 |
| HRP20200852T1 (hr) | 2020-08-21 |
| MX2018002759A (es) | 2018-08-01 |
| WO2017041622A1 (zh) | 2017-03-16 |
| DK3348546T3 (da) | 2020-07-06 |
| US10150739B2 (en) | 2018-12-11 |
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