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HU9301801D0 - Method for producing synthetic leader sequences - Google Patents

Method for producing synthetic leader sequences

Info

Publication number
HU9301801D0
HU9301801D0 HU931801A HUP9301801A HU9301801D0 HU 9301801 D0 HU9301801 D0 HU 9301801D0 HU 931801 A HU931801 A HU 931801A HU P9301801 A HUP9301801 A HU P9301801A HU 9301801 D0 HU9301801 D0 HU 9301801D0
Authority
HU
Hungary
Prior art keywords
leader sequences
producing synthetic
synthetic leader
producing
sequences
Prior art date
Application number
HU931801A
Other languages
Hungarian (hu)
Inventor
Lars Christiansen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of HU9301801D0 publication Critical patent/HU9301801D0/en
Publication of HUT68751A publication Critical patent/HUT68751A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/036—Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Consolidation Of Soil By Introduction Of Solidifying Substances Into Soil (AREA)
  • Working Measures On Existing Buildindgs (AREA)
  • Prevention Of Electric Corrosion (AREA)
  • Bridges Or Land Bridges (AREA)
  • Building Environments (AREA)
HU9301801A 1990-12-19 1991-12-18 A method of constructing synthetic leader sequences HUT68751A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK300090A DK300090D0 (en) 1990-12-19 1990-12-19 PROCEDURE FOR PREPARING LEADER SEQUENCES

Publications (2)

Publication Number Publication Date
HU9301801D0 true HU9301801D0 (en) 1993-10-28
HUT68751A HUT68751A (en) 1995-07-28

Family

ID=8118017

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9301801A HUT68751A (en) 1990-12-19 1991-12-18 A method of constructing synthetic leader sequences

Country Status (17)

Country Link
EP (1) EP0563175A1 (en)
JP (1) JPH06503957A (en)
KR (1) KR930703450A (en)
AU (1) AU660161B2 (en)
CA (1) CA2098731A1 (en)
CZ (1) CZ119293A3 (en)
DK (1) DK300090D0 (en)
FI (1) FI932831A0 (en)
HU (1) HUT68751A (en)
IE (1) IE914433A1 (en)
IL (1) IL100408A0 (en)
MX (1) MX9102684A (en)
NZ (1) NZ241011A (en)
PT (1) PT99848A (en)
SK (1) SK62593A3 (en)
WO (1) WO1992011378A1 (en)
ZA (1) ZA919932B (en)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI92601C (en) * 1992-03-11 1994-12-12 Marja Makarow Procedure for secretion of yeast beneficial proteins
US5538863A (en) * 1993-07-01 1996-07-23 Immunex Corporation Expression system comprising mutant yeast strain and expression vector encoding synthetic signal peptide
US5639642A (en) * 1994-06-16 1997-06-17 Novo Nordisk A/S Synthetic leader peptide sequences
ZA954983B (en) * 1994-06-17 1996-02-14 Novo Nordisk As N-terminally extended proteins expressed in yeast
US6500645B1 (en) 1994-06-17 2002-12-31 Novo Nordisk A/S N-terminally extended proteins expressed in yeast
HRP940432B1 (en) * 1994-08-05 2003-10-31 Pliva Pharm & Chem Works Dna sequences encoding biosynthetic insulin precursors and process for preparation of insulin
CN102080070B (en) 1995-03-17 2016-01-20 诺沃奇梅兹有限公司 new endoglucanase
PL187095B1 (en) 1996-03-01 2004-05-31 Novo Nordisk As Application of a pharmaceutic composition containing an appetite inhibiting peptide
US6017731A (en) 1996-12-13 2000-01-25 Chiron Corporation Method for expression of heterologous proteins in yeast
EP1049790A1 (en) 1998-01-23 2000-11-08 Novo Nordisk A/S Process for making desired polypeptides in yeast
CA2392844A1 (en) 1999-12-29 2001-07-12 Novo Nordisk A/S Method for making insulin precursors and insulin precursor analogues having improved fermentation yield in yeast
AT410217B (en) * 2000-06-15 2003-03-25 Cistem Biotechnologies Gmbh VECTOR AND A METHOD FOR THE EXPRESSION AND SELECTION OF RANDOMIZED PEPTIDE SEQUENCES
HUP0401124A3 (en) 2001-03-22 2006-01-30 Novo Nordisk Healthcare Ag Coagulation factor vii derivatives
ES2376694T3 (en) 2001-09-27 2012-03-16 Novo Nordisk Health Care Ag HUMAN COAGULATION FACTOR VII POLIPED PEPDES VII.
CN1863908B (en) 2003-09-09 2010-08-04 诺和诺德医疗保健公司 Coagulation factor vii polypeptides
JP2007532096A (en) 2003-11-14 2007-11-15 ノボ　ノルディスク　アクティーゼルスカブ Method for producing acylated insulin
AU2004295023A1 (en) 2003-12-03 2005-06-16 Novo Nordisk A/S Single-chain insulin
WO2005078116A1 (en) * 2004-01-16 2005-08-25 Qiuyun Liu A method of isolating antibacterial peptides and the isolated peptides thereof
US8034326B2 (en) 2005-04-18 2011-10-11 Novo Nordisk A/S IL-21 variants
WO2007020256A1 (en) 2005-08-16 2007-02-22 Novo Nordisk A/S Method for making mature insulin polypeptides
US20090055942A1 (en) 2005-09-14 2009-02-26 Novo Nordisk Healthcare A/G Human Coagulation Factor VII Polypeptides
ATE482977T1 (en) 2006-02-27 2010-10-15 Novo Nordisk As INSULIN DERIVATIVES
WO2008037735A1 (en) 2006-09-27 2008-04-03 Novo Nordisk A/S Method for making maturated insulin polypeptides
EP2178909B1 (en) 2007-08-13 2015-10-21 Novo Nordisk A/S Rapid acting insulin analogues
EP2178912B1 (en) 2007-08-15 2015-07-08 Novo Nordisk A/S Insulin analogues with an acyl and aklylene glycol moiety
WO2009022006A1 (en) 2007-08-15 2009-02-19 Novo Nordisk A/S Insulins with an acyl moiety comprising repeating units of alkylene glycol containing amino acids
WO2010103038A1 (en) 2009-03-11 2010-09-16 Novo Nordisk A/S Interleukin-21 variants having antagonistic binding to the il-21 receptor
CA2767755C (en) 2009-07-17 2021-10-12 Rigshospitalet Inhibitors of complement activation
WO2011064282A1 (en) 2009-11-25 2011-06-03 Novo Nordisk A/S Method for making polypeptides
JP5931738B2 (en) 2009-12-01 2016-06-08 ノヴォ ノルディスク アー／エス Novel peptidyl alpha-hydroxyglycine alpha-amidated lyase
CN102791730A (en) 2010-01-22 2012-11-21 诺沃—诺迪斯克有限公司 Process for preparing FGF-21 with low degree of O-glycosylation
AU2011222883B2 (en) 2010-03-05 2016-05-26 Omeros Corporation Chimeric inhibitor molecules of complement activation
WO2012015692A2 (en) * 2010-07-28 2012-02-02 Smartcells, Inc. Recombinantly expressed insulin polypeptides and uses thereof
JP6517018B2 (en) 2012-02-09 2019-05-22 ヴァー２・ファーマシューティカルズ・アンパルトセルスカブＶＡＲ２ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ ＡｐＳ Targeting chondroitin sulfate glycans
WO2014060401A1 (en) 2012-10-15 2014-04-24 Novo Nordisk Health Care Ag Coagulation factor vii polypeptides
CN105308067B (en) 2013-06-07 2020-07-24 诺和诺德股份有限公司 Method for preparing mature insulin polypeptide
CN106029688A (en) * 2014-02-28 2016-10-12 诺和诺德股份有限公司 Mating factor alpha propeptide variants
US20210278406A1 (en) 2018-07-13 2021-09-09 Varct Diagnostic Aps Isolation of circulating cells of fetal origin using recombinant malaria protein var2csa

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK463887D0 (en) * 1987-09-07 1987-09-07 Novo Industri As GAERLEADER
CA1340772C (en) * 1987-12-30 1999-09-28 Patricia Tekamp-Olson Expression and secretion of heterologous protiens in yeast employing truncated alpha-factor leader sequences
HU213571B (en) * 1988-07-23 1997-08-28 Delta Biotechnology Ltd Process for producing peptides and dna sequences
DK105489D0 (en) * 1989-03-03 1989-03-03 Novo Nordisk As POLYPEPTIDE

Also Published As

Publication number Publication date
WO1992011378A1 (en) 1992-07-09
NZ241011A (en) 1993-04-28
IE914433A1 (en) 1992-07-01
FI932831L (en) 1993-06-18
EP0563175A1 (en) 1993-10-06
PT99848A (en) 1993-06-30
HUT68751A (en) 1995-07-28
SK62593A3 (en) 1993-10-06
ZA919932B (en) 1992-08-26
DK300090D0 (en) 1990-12-19
KR930703450A (en) 1993-11-30
FI932831A7 (en) 1993-06-18
FI932831A0 (en) 1993-06-18
JPH06503957A (en) 1994-05-12
AU660161B2 (en) 1995-06-15
MX9102684A (en) 1992-06-01
CA2098731A1 (en) 1992-06-19
CZ119293A3 (en) 1994-02-16
IL100408A0 (en) 1992-09-06
AU9134891A (en) 1992-07-22

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Legal Events

Date Code Title Description
DFD9 Temporary protection cancelled due to non-payment of fee