[go: up one dir, main page]

HU902472D0 - Process for the production of freeze-dryed pharmaceutical products containing active agents - Google Patents

Process for the production of freeze-dryed pharmaceutical products containing active agents

Info

Publication number
HU902472D0
HU902472D0 HU902472A HU247290A HU902472D0 HU 902472 D0 HU902472 D0 HU 902472D0 HU 902472 A HU902472 A HU 902472A HU 247290 A HU247290 A HU 247290A HU 902472 D0 HU902472 D0 HU 902472D0
Authority
HU
Hungary
Prior art keywords
freeze
dryed
production
active agents
products containing
Prior art date
Application number
HU902472A
Other languages
Hungarian (hu)
Other versions
HUT54885A (en
HU204993B (en
Inventor
Seigo Ueda
Takashi Shiokari
Kunio Hashi
Akira Kusai
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of HU902472D0 publication Critical patent/HU902472D0/en
Publication of HUT54885A publication Critical patent/HUT54885A/en
Publication of HU204993B publication Critical patent/HU204993B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B5/00—Drying solid materials or objects by processes not involving the application of heat
    • F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
    • F26B5/06—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23B—PRESERVATION OF FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES; CHEMICAL RIPENING OF FRUIT OR VEGETABLES
    • A23B2/00—Preservation of foods or foodstuffs, in general
    • A23B2/90—Preservation of foods or foodstuffs, in general by drying or kilning; Subsequent reconstitution
    • A23B2/92—Freeze drying
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Electrophonic Musical Instruments (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

In a freeze-drying method for producing a dried pharmaceutical compound or preparation, a first liquid is frozen, a second liquid is added to the frozen first liquid and is frozen thereon, and the frozen first and second liquids are freeze-dried together, in which at least one of said first and second liquids contains said pharmaceutical compound or preparation dissolved or suspended therein. The other liquid or liquids may be pure solvent (generally water) or may contain one or more other substances.
HU902472A 1989-04-18 1990-04-18 Process for producing freeze-dried pharmaceuticak compositions HU204993B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9856189 1989-04-18

Publications (3)

Publication Number Publication Date
HU902472D0 true HU902472D0 (en) 1990-08-28
HUT54885A HUT54885A (en) 1991-04-29
HU204993B HU204993B (en) 1992-03-30

Family

ID=14223093

Family Applications (1)

Application Number Title Priority Date Filing Date
HU902472A HU204993B (en) 1989-04-18 1990-04-18 Process for producing freeze-dried pharmaceuticak compositions

Country Status (17)

Country Link
US (1) US5044091B1 (en)
EP (1) EP0394050B1 (en)
JP (1) JPH07116022B2 (en)
KR (1) KR950007908B1 (en)
AT (1) ATE210427T1 (en)
AU (1) AU624494B2 (en)
CA (1) CA2014714C (en)
DE (1) DE69033874T2 (en)
DK (1) DK0394050T3 (en)
ES (1) ES2165839T3 (en)
FI (1) FI104360B (en)
HK (1) HK1010685A1 (en)
HU (1) HU204993B (en)
NO (1) NO180801C (en)
NZ (1) NZ233344A (en)
PH (1) PH27522A (en)
ZA (1) ZA902909B (en)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5215756A (en) * 1989-12-22 1993-06-01 Gole Dilip J Preparation of pharmaceutical and other matrix systems by solid-state dissolution
US5169834A (en) * 1990-11-30 1992-12-08 American Cyanamid Company Compositions and method for reducing vial breakage during lyophilization
GR910100193A (en) * 1991-05-03 1993-03-31 Mediventures Inc Preparation of pharmaceutical and other matrix systems by solid-state dissolution
US5362442A (en) * 1993-07-22 1994-11-08 2920913 Canada Inc. Method for sterilizing products with gamma radiation
US20040067157A1 (en) * 1993-07-22 2004-04-08 Clearant, Inc. Methods for sterilizing biological materials
DE19547973C2 (en) * 1995-12-21 1999-08-12 Plantamed Arzneimittel Gmbh Process for the gentle reduction of germs in pharmaceutical preparations
IL120202A (en) * 1996-03-07 2001-03-19 Akzo Nobel Nv Container with freeze-dried vaccine components
WO1999037288A1 (en) * 1998-01-21 1999-07-29 Takeda Chemical Industries, Ltd. Lyophilization method for sustained-release preparations
US20040086420A1 (en) * 2000-03-23 2004-05-06 Macphee Martin J. Methods for sterilizing serum or plasma
US6682695B2 (en) * 2001-03-23 2004-01-27 Clearant, Inc. Methods for sterilizing biological materials by multiple rates
US6696060B2 (en) 2001-06-14 2004-02-24 Clearant, Inc. Methods for sterilizing preparations of monoclonal immunoglobulins
EG24184A (en) * 2001-06-15 2008-10-08 Otsuka Pharma Co Ltd Dry powder inhalation system for transpulmonary
US6946098B2 (en) 2001-08-10 2005-09-20 Clearant, Inc. Methods for sterilizing biological materials
US6749851B2 (en) 2001-08-31 2004-06-15 Clearant, Inc. Methods for sterilizing preparations of digestive enzymes
US7252799B2 (en) * 2001-08-31 2007-08-07 Clearant, Inc. Methods for sterilizing preparations containing albumin
US20030095890A1 (en) * 2001-09-24 2003-05-22 Shirley Miekka Methods for sterilizing biological materials containing non-aqueous solvents
US6783968B2 (en) 2001-09-24 2004-08-31 Clearant, Inc. Methods for sterilizing preparations of glycosidases
US20030185702A1 (en) * 2002-02-01 2003-10-02 Wilson Burgess Methods for sterilizing tissue
US20110091353A1 (en) * 2001-09-24 2011-04-21 Wilson Burgess Methods for Sterilizing Tissue
US20030124023A1 (en) * 2001-12-21 2003-07-03 Wilson Burgess Method of sterilizing heart valves
US7387796B2 (en) * 2002-01-30 2008-06-17 Hebert Rolland F Stable compositions of S-adenosyl-l-methionine with dextran
US20030180181A1 (en) * 2002-02-01 2003-09-25 Teri Greib Methods for sterilizing tissue
US6908591B2 (en) * 2002-07-18 2005-06-21 Clearant, Inc. Methods for sterilizing biological materials by irradiation over a temperature gradient
US20040013562A1 (en) * 2002-07-18 2004-01-22 Wilson Burgess Methods for sterilizing milk.
JP2006111532A (en) * 2004-10-12 2006-04-27 Yoshindo:Kk Panipenem-containing double bag-type preparation
EP1870649A1 (en) * 2006-06-20 2007-12-26 Octapharma AG Lyophilisation targetting defined residual moisture by limited desorption energy levels
TWI343262B (en) * 2006-09-26 2011-06-11 Schering Corp Rapidly disintegrating lyophilized oral formulations of a thrombin receptor antagonist
US10548839B2 (en) * 2010-03-16 2020-02-04 Wei Tian Process of manufacturing a lyophilized fast dissolving, multi-phasic dosage form
EP2864724B1 (en) 2012-06-26 2018-10-24 Bioneer A/S Syringe with a hollow plunger for lyophilized products
EP3532035B1 (en) 2016-10-25 2023-06-07 Catalent U.K. Swindon Zydis Limited Compositions of different densities for fast disintegrating multi-layer tablet

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB797774A (en) * 1955-03-02 1958-07-09 Armour & Co Improvements in and relating to the production and packaging of stratiform products
US3616543A (en) * 1969-10-31 1971-11-02 Merck & Co Inc Method of producing a multicomponent lyophilized product
FR2109201A6 (en) * 1970-10-07 1972-05-26 Air Liquide
EP0069176A1 (en) * 1981-07-03 1983-01-12 American Home Products Corporation Method of obtaining a lyophilized product
US4433558A (en) * 1981-08-25 1984-02-28 Cheng Chen Yen Parallel contact distillative freezing process for separating volatile mixtures and apparatuses for use therein
DE3264450D1 (en) * 1981-12-11 1985-08-01 Wyeth John & Brother Ltd Process and apparatus for freezing a liquid medium
US4430807A (en) * 1982-05-17 1984-02-14 The Dow Chemical Company Process for drying water-wet membranes
JPS6168412A (en) * 1984-09-10 1986-04-08 Fujisawa Pharmaceut Co Ltd Freeze-drying of medicine
IL78930A0 (en) * 1985-07-29 1986-09-30 Abbott Lab Lyophilized emulsion compositions for parenteral administration
FR2601702A1 (en) * 1986-07-21 1988-01-22 Atochem METHYLENE CHLORIDE COMPOSITION - USE THEREOF FOR DEGREASING METALS

Also Published As

Publication number Publication date
HUT54885A (en) 1991-04-29
EP0394050A2 (en) 1990-10-24
FI901947A0 (en) 1990-04-18
US5044091A (en) 1991-09-03
NZ233344A (en) 1991-05-28
KR900015715A (en) 1990-11-10
NO901691D0 (en) 1990-04-17
CA2014714C (en) 2000-07-18
US5044091B1 (en) 1997-12-30
DK0394050T3 (en) 2002-02-11
JPH0347115A (en) 1991-02-28
NO901691L (en) 1990-10-19
ES2165839T3 (en) 2002-04-01
PH27522A (en) 1993-08-18
NO180801C (en) 1997-07-02
ZA902909B (en) 1991-12-24
KR950007908B1 (en) 1995-07-21
HK1010685A1 (en) 1999-06-25
DE69033874T2 (en) 2002-08-29
NO180801B (en) 1997-03-24
EP0394050B1 (en) 2001-12-12
CA2014714A1 (en) 1990-10-18
FI104360B (en) 2000-01-14
DE69033874D1 (en) 2002-01-24
AU5328990A (en) 1990-10-25
HU204993B (en) 1992-03-30
JPH07116022B2 (en) 1995-12-13
EP0394050A3 (en) 1992-06-10
ATE210427T1 (en) 2001-12-15
AU624494B2 (en) 1992-06-11

Similar Documents

Publication Publication Date Title
HU902472D0 (en) Process for the production of freeze-dryed pharmaceutical products containing active agents
GB9320668D0 (en) Liposomes containing particulare materials
HU906341D0 (en) Process for producing peptonic derivatives modified with sugar and pharmaceutical preparatives containing these compounds as active substance
NO862689D0 (en) DEHYDRATIZED Capsule, AND PROCEDURE FOR PREPARING SUCH A.
HUT52752A (en) Fungicides containing as active substance acyl-aminbenzamids and process for production of the active substances
HUT47570A (en) Insecticides containing as active substance 3-substituated-1-/chlor-tiasole-5-il-methil/-2-nitroamin-1,3-diaza-cycloalkans and process for production of the active substances
AU604070B2 (en) Modification of alginates or other uronic acid containing compounds
HUT43928A (en) Herbicides comprising 1-substituted-1h-imidazole-5-carboxylic acid derivatives as active substance and process for preparing the active substances
HUT43986A (en) Insecticides containing as active substance derivatives of diphenil ether and process for production of the active substances
HUT44023A (en) Herbicides containing as active substance derivatives of cyclohexenan and process for production of the active substances
EP0248362A3 (en) Process for the production of an active protein from a biologically inactive form
HUT48799A (en) Herbicides containing as active substance derivatives of triazolinon and process for production of the active substances
HUT44764A (en) Process for producing new sulfonamidoethyl derivatives and pharmaceutical preparations comprising them as active substance
HUT48797A (en) Insecticides, acarycides and nematocides containing as active substance derivatives of aryl-pirrol and process for production of the active substances
HUT44018A (en) Insecticides and acaricides containing as active substance 5-amin-1-phenil-pirasole derivatives and process for production of the active substances
HUT43866A (en) Process for preparing novel antrocycline derivatives and pharmaceuticals comprising the same as active substance
HUT43318A (en) Fungicides comprising 2-cyano-benzimidazole derivatives as active substance and process for preparing the active substances
HUT44488A (en) Fungicides containing as active substance derivatives of decahydronaft-2-il-alkyl-amin and process for production of the active substance
HUT45839A (en) Fungicides containing as active substance 3-sulphenilmalein-imid derivatives and process for production of these active substances
HUT42918A (en) Insecticides and acaricides containing as active substance derivatives of 1,3,5-oxadiazin-2-on and process for production of the active substance
HUT45025A (en) Fungicides containing as active substance imidasolederivatives and process for production of the active substance
HUT46682A (en) Fungicides containing as active substance derivatives of new amin-tiethil-izoxasolidine and process for production of the active substances
DE3672387D1 (en) PRODUCTION OF CELLADHAESION INHIBITORS, ANTIADHAESINS SO OBTAINED AND MEDICINAL PRODUCTS AND FOODS CONTAINING THEM.
DE3790355T (en) METHOD FOR THE PRODUCTION OF LIQUID ACID-NEUTRALIZING PHARMACEUTICAL PREPARATIONS WITH LARGE ACID-BINDING CAPACITY, DELAYED EFFECTIVENESS AND ENHANCED BIOAVAILABILITY
HUT44440A (en) Process for preparing pvp-i complex and stable pharmaceutical comprising the same as active substance

Legal Events

Date Code Title Description
HMM4 Cancellation of final prot. due to non-payment of fee
MM4A Lapse of definitive patent protection due to non-payment of fees