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HRP920960B1 - Solutionless pharmaceutical preparations for oral use retardely releasing an active substance and a process for the preparation thereof - Google Patents

Solutionless pharmaceutical preparations for oral use retardely releasing an active substance and a process for the preparation thereof

Info

Publication number
HRP920960B1
HRP920960B1 HRP-1618/91A HRP920960A HRP920960B1 HR P920960 B1 HRP920960 B1 HR P920960B1 HR P920960 A HRP920960 A HR P920960A HR P920960 B1 HRP920960 B1 HR P920960B1
Authority
HR
Croatia
Prior art keywords
pharmaceutical preparations
solutionless
retardely
releasing
pct
Prior art date
Application number
HRP-1618/91A
Other languages
English (en)
Inventor
Bernard Sczepanik
Original Assignee
Bernard Sczepanik
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6415859&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP920960(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bernard Sczepanik filed Critical Bernard Sczepanik
Publication of HRP920960A2 publication Critical patent/HRP920960A2/xx
Publication of HRP920960B1 publication Critical patent/HRP920960B1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Inorganic Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
HRP-1618/91A 1990-10-08 1992-10-02 Solutionless pharmaceutical preparations for oral use retardely releasing an active substance and a process for the preparation thereof HRP920960B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4031881A DE4031881C2 (de) 1990-10-08 1990-10-08 Lösungsmittelfreie, oral zu verabreichende pharmazeutische Zubereitung mit verzögerter Wirkstoffreisetzung und Verfahren zu deren Herstellung
YU161891A YU48766B (sh) 1990-10-08 1991-10-03 Postupak za dobijanje farmaceutskog preparata za oralnu primenu sa usporenim oslobađanjem aktivne supstance bez rastvarača

Publications (2)

Publication Number Publication Date
HRP920960A2 HRP920960A2 (en) 1995-08-31
HRP920960B1 true HRP920960B1 (en) 1998-10-31

Family

ID=6415859

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP-1618/91A HRP920960B1 (en) 1990-10-08 1992-10-02 Solutionless pharmaceutical preparations for oral use retardely releasing an active substance and a process for the preparation thereof

Country Status (24)

Country Link
US (1) US5453283A (fi)
EP (1) EP0552227B2 (fi)
JP (1) JP3233929B2 (fi)
KR (1) KR0166599B1 (fi)
AT (1) ATE116843T1 (fi)
CA (1) CA2093666C (fi)
CZ (1) CZ284923B6 (fi)
DE (2) DE4031881C2 (fi)
DK (1) DK0552227T4 (fi)
ES (1) ES2067250T5 (fi)
FI (1) FI108401B (fi)
GR (1) GR3015131T3 (fi)
HR (1) HRP920960B1 (fi)
HU (2) HUT64211A (fi)
IE (1) IE76142B1 (fi)
LV (1) LV11002B (fi)
PL (1) PL167593B1 (fi)
PT (1) PT99168B (fi)
RU (1) RU2101009C1 (fi)
SI (1) SI9111618B (fi)
SK (1) SK279446B6 (fi)
UA (1) UA26449C2 (fi)
WO (1) WO1992005774A1 (fi)
YU (1) YU48766B (fi)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3459421B2 (ja) * 1992-12-23 2003-10-20 サイテック ソチエタ レスポンサビリタ リミテ 調節された開放医薬形の調製法及びそのようにして得られた医薬形
IL109460A (en) 1993-05-10 1998-03-10 Euro Celtique Sa Controlled release formulation comprising tramadol
US5879705A (en) * 1993-07-27 1999-03-09 Euro-Celtique S.A. Sustained release compositions of morphine and a method of preparing pharmaceutical compositions
US5891471A (en) * 1993-11-23 1999-04-06 Euro-Celtique, S.A. Pharmaceutical multiparticulates
KR100354702B1 (ko) * 1993-11-23 2002-12-28 유로-셀티크 소시에떼 아노뉨 약학조성물의제조방법및서방형조성물
US5843480A (en) * 1994-03-14 1998-12-01 Euro-Celtique, S.A. Controlled release diamorphine formulation
DE4418837A1 (de) * 1994-05-30 1995-12-07 Bayer Ag Thermisches Granulierverfahren
GB9422154D0 (en) 1994-11-03 1994-12-21 Euro Celtique Sa Pharmaceutical compositions and method of producing the same
US5965161A (en) 1994-11-04 1999-10-12 Euro-Celtique, S.A. Extruded multi-particulates
DE19504832A1 (de) * 1995-02-14 1996-08-22 Basf Ag Feste Wirkstoff-Zubereitungen
WO1996031197A1 (en) * 1995-04-03 1996-10-10 Abbott Laboratories Homogeneous mixtures of low temperature-melting drugs and additives for controlled release
HRP970485A2 (en) 1996-09-13 1998-08-31 Joerg Rosenberg Process for producing solid pharmaceutical forms
US5851555A (en) * 1997-08-15 1998-12-22 Fuisz Technologies Ltd. Controlled release dosage forms containing water soluble drugs
UA73092C2 (uk) * 1998-07-17 2005-06-15 Брістол-Майерс Сквібб Компані Таблетка з ентеросолюбільним покриттям і спосіб її приготування
DE19918325A1 (de) 1999-04-22 2000-10-26 Euro Celtique Sa Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion
DE10029201A1 (de) 2000-06-19 2001-12-20 Basf Ag Verfahren zur Herstellung fester oraler Darreichungsformen mit retardierender Wirkstoffreisetzung
EP1337283A4 (en) * 2000-10-27 2005-05-18 Nitromed Inc METHODS OF TREATING VASCULAR DISEASES CHARACTERIZED BY NITROGEN MONOXIDE INSUFFICIENCY
GB0209265D0 (en) 2002-04-23 2002-06-05 Novartis Ag Organic compounds
US20040029959A1 (en) * 2002-08-08 2004-02-12 John Devane Isosorbide mononitrate compositions and methods of their use
RU2267318C1 (ru) * 2004-05-25 2006-01-10 Закрытое акционерное общество "ФАРМАПЭК" Пролонгированный антиангинальный препарат изосорбида динитрата и способ его получения
MY148074A (en) * 2005-05-10 2013-02-28 Novartis Ag Pharmaceutical compositions comprising imatinib and a release retardant
RU2408368C2 (ru) 2005-06-27 2011-01-10 Биовэйл Лэборэториз Интернэшнл С.Р.Л. Препараты соли бупропиона с модифицированным высвобождением
US20090246276A1 (en) 2008-01-28 2009-10-01 Graham Jackson Pharmaceutical Compositions
KR101659983B1 (ko) * 2012-12-31 2016-09-26 주식회사 삼양바이오팜 용융 압출된 방출 제어용 약학 조성물, 및 이를 포함하는 경구용 제제
WO2017086835A1 (ru) * 2015-11-17 2017-05-26 Общество С Ограниченной Ответственностью "Валента-Интеллект" Фармацевтическая композиция, обладающая терапевтическим эффектом в отношении демиелинизирующих заболеваний (варианты)
WO2019087084A1 (en) 2017-11-02 2019-05-09 Eman Biodiscoveries Sd. Bhd. Extract of orthosiphon stamineus, formulations, and uses thereof

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL297357A (fi) * 1962-08-31
US3308217A (en) * 1965-02-09 1967-03-07 Lowy Lawrence Method of granulating materials for subsequent forming into tablets
ZA723701B (en) * 1971-06-04 1973-04-25 Boehringer Mannheim Gmbh Process for the granulation of powdered tablet masses
FR2581541B1 (fr) * 1985-05-09 1988-05-20 Rhone Poulenc Sante Nouvelles compositions pharmaceutiques permettant la liberation prolongee d'un principe actif et leur procede de preparation
US5246714A (en) * 1985-10-11 1993-09-21 Aktiebolaget Hassle Drug preparation
DE3612212A1 (de) * 1986-04-11 1987-10-15 Basf Ag Verfahren zur herstellung von festen pharmazeutischen formen
DE3612211A1 (de) * 1986-04-11 1987-10-15 Basf Ag Kontinuierliches verfahren zum tablettieren
IT1200217B (it) * 1986-09-30 1989-01-05 Valducci Roberto Membrana per uso farmaceutico ed industriale
DE3743946A1 (de) * 1987-09-01 1989-03-09 Lohmann Gmbh & Co Kg Vorrichtung zur abgabe von nitroglycerin an die haut, verfahren zu ihrer herstellung sowie ihre verwendung
DE3743947A1 (de) * 1987-09-01 1989-03-09 Lohmann Gmbh & Co Kg Vorrichtung zur gesteuerten abgabe von nicotin, verfahren zu ihrer herstellung sowie ihre verwendung
DE3743945A1 (de) * 1987-09-01 1989-03-09 Lohmann Gmbh & Co Kg Vorrichtung zur abgabe von stoffen, verfahren zu ihrer herstellung sowie ihre verwendung
DE3812567A1 (de) * 1988-04-15 1989-10-26 Basf Ag Verfahren zur herstellung pharmazeutischer mischungen
DE3812799A1 (de) * 1988-04-16 1989-10-26 Sanol Arznei Schwarz Gmbh Oral zu verabreichende pharmazeutische zubereitung mit kontrollierter wirkstofffreisetzung und verfahren zu deren herstellung
DE3830353A1 (de) * 1988-09-07 1990-03-15 Basf Ag Verfahren zur kontinuierlichen herstellung von festen pharmazeutischen formen
DK469989D0 (da) * 1989-09-22 1989-09-22 Bukh Meditec Farmaceutisk praeparat
US5262173A (en) * 1992-03-02 1993-11-16 American Cyanamid Company Pulsatile once-a-day delivery systems for minocycline

Also Published As

Publication number Publication date
DK0552227T3 (da) 1995-03-27
IE913592A1 (en) 1992-04-08
DE4031881A1 (de) 1992-04-09
HUT64211A (en) 1993-12-28
FI931576A0 (fi) 1993-04-07
WO1992005774A1 (de) 1992-04-16
LV11002B (en) 1996-06-20
PT99168B (pt) 1999-04-30
DE59104271D1 (de) 1995-02-23
PT99168A (pt) 1992-09-30
CZ284923B6 (cs) 1999-04-14
FI108401B (fi) 2002-01-31
YU48766B (sh) 1999-12-27
SI9111618A (en) 1997-12-31
YU161891A (sh) 1994-06-10
LV11002A (lv) 1996-02-20
ES2067250T5 (es) 1999-02-01
FI931576L (fi) 1993-04-07
SK279446B6 (sk) 1998-11-04
UA26449C2 (uk) 1999-08-30
DE4031881C2 (de) 1994-02-24
EP0552227A1 (de) 1993-07-28
DK0552227T4 (da) 1999-07-19
SI9111618B (sl) 1999-08-31
EP0552227B1 (de) 1995-01-11
CA2093666C (en) 1998-05-19
US5453283A (en) 1995-09-26
CA2093666A1 (en) 1992-04-09
CS305091A3 (en) 1992-04-15
HU9300995D0 (en) 1993-07-28
KR930701963A (ko) 1993-09-08
ES2067250T3 (es) 1995-03-16
IE76142B1 (en) 1997-10-08
RU2101009C1 (ru) 1998-01-10
KR0166599B1 (ko) 1999-01-15
JP3233929B2 (ja) 2001-12-04
GR3015131T3 (en) 1995-05-31
PL167593B1 (pl) 1995-09-30
HU211845A9 (en) 1995-12-28
EP0552227B2 (de) 1998-11-04
JPH06501685A (ja) 1994-02-24
ATE116843T1 (de) 1995-01-15
HRP920960A2 (en) 1995-08-31

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