HRP20240251T1 - Pediococcus acidilactici cect 9879 za regulaciju glukoze u krvi - Google Patents
Pediococcus acidilactici cect 9879 za regulaciju glukoze u krvi Download PDFInfo
- Publication number
- HRP20240251T1 HRP20240251T1 HRP20240251TT HRP20240251T HRP20240251T1 HR P20240251 T1 HRP20240251 T1 HR P20240251T1 HR P20240251T T HRP20240251T T HR P20240251TT HR P20240251 T HRP20240251 T HR P20240251T HR P20240251 T1 HRP20240251 T1 HR P20240251T1
- Authority
- HR
- Croatia
- Prior art keywords
- strain
- preparation
- cect
- pediococcus acidilactici
- diabetes
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/742—Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K2035/11—Medicinal preparations comprising living procariotic cells
- A61K2035/115—Probiotics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Emergency Medicine (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Inorganic Chemistry (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Claims (14)
1. Soj Pediococcus acidilactici pohranjen u "Colección Española de Cultivos Tipo" (CECT) s identifikacijskom referencom CECT 9879.
2. Pripravak koji sadrži učinkovitu količinu soja kako je definirano u prethodnom zahtjevu.
3. Pripravak prema prethodnom zahtjevu, naznačen time što je učinkovita količina od 10<4> do 10<12> bakterijskih stanica/g ili mL ukupnog pripravka.
4. Pripravak prema bilo kojem od zahtjeva 2-3, koji je oralni pripravak.
5. Pripravak prema prethodnom zahtjevu, koji je hrana ili proizvod za životinje, sastojak hrane ili hrane za životinje, dodatak hrani ili hrani za životinje ili nutricijski proizvod.
6. Pripravak prema prethodnom zahtjevu, koji je funkcionalna hrana ili proizvod za životinje.
7. Pripravak prema bilo kojem od zahtjeva 2-4, koji je farmaceutski ili nutraceutički pripravak i također sadrži farmaceutski prihvatljive ekscipijente i nosače.
8. Soj kako je definiran u zahtjevu 1 ili pripravak kako je definiran u bilo kojem od zahtjeva 2-7, za uporabu kao probiotik, ili za uporabu kao lijek.
9. Soj kako je definiran u zahtjevu 1 ili pripravak kako je definiran u bilo kojem od zahtjeva 2-7 za uporabu u terapeutskoj regulaciji razine glukoze u krvi kod subjekta kojem je to potrebno.
10. Soj kako je definiran u zahtjevu 1 ili pripravak kako je definiran u bilo kojem od zahtjeva 2-7 za uporabu u prevenciji ili liječenju hiperglikemije i/ili stanja povezanog s hiperglikemijom.
11. Soj ili pripravak za uporabu prema prethodnom zahtjevu, naznačen time što je stanje povezano s hiperglikemijom odabrano između smanjene glikemije natašte (IFG), smanjene tolerancije glukoze (IGT), postprandijalne hiperglikemije, intolerancije glukoze, inzulinske rezistencije, predijabetesa, dijabetesa tipa I, dijabetesa tipa II, monogenog dijabetesa, neonatalnog dijabetesa melitus, steroidnog dijabetesa i gestacijskog dijabetesa.
12. Soj ili pripravak za uporabu prema bilo kojem od zahtjeva 8-11, naznačen time što je soj ili pripravak za uporabu u kombinaciji s prebiotikom.
13. Postupak za dobivanje stanične suspenzije sposobne za život izvedene iz Pediococcus acidilactici CECT 9879, naznačen time što postupak obuhvaća: (i) inokulaciju soja Pediococcus acidilactici CECT 9879 u medij kulture, (ii) podvrgavanje inokuliranog medija kulture iz koraka (i) uvjetima prikladnim za rast soja, i (iii) izborno podvrgavanje medija dobivenog iz koraka (ii) koraku koncentriranje.
14. Metoda za dobivanje mutanta Pediococcus acidilactici CECT 9879, koja sadrži korak podvrgavanja soja Pediococcus acidilactici CECT 9879 DNA rekombinantnoj tehnici, na primjer mutagenezi, ili uvjetima za stvaranje spontanih mutacija, na primjer UV svjetlu.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP19383179 | 2019-12-20 | ||
| PCT/EP2020/087284 WO2021123355A1 (en) | 2019-12-20 | 2020-12-18 | Probiotics for regulating blood glucose |
| EP20845776.2A EP4076484B1 (en) | 2019-12-20 | 2020-12-18 | Pediococcus acidilactici cect 9879 for regulating blood glucose |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20240251T1 true HRP20240251T1 (hr) | 2024-05-24 |
Family
ID=69167589
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20240251TT HRP20240251T1 (hr) | 2019-12-20 | 2020-12-18 | Pediococcus acidilactici cect 9879 za regulaciju glukoze u krvi |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20230038352A1 (hr) |
| EP (2) | EP4076484B1 (hr) |
| ES (1) | ES2971942T3 (hr) |
| HR (1) | HRP20240251T1 (hr) |
| HU (1) | HUE065458T2 (hr) |
| WO (1) | WO2021123355A1 (hr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR3120788B1 (fr) * | 2021-03-22 | 2024-04-19 | Ophtalmis | Composition nutraceutique pour le traitement et la prevention des troubles oculaires |
| EP4620479A1 (en) | 2024-03-21 | 2025-09-24 | Genbioma Aplicaciones, S.L. | Postbiotic preparation comprising pediococcus acidilactici for preventing or treating obesity |
| CN118620807B (zh) * | 2024-08-15 | 2024-10-22 | 山东健源生物科技有限公司 | 一株具有减肥、降血糖作用的乳酸片球菌及其后生元和应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2949064B1 (fr) * | 2009-08-14 | 2011-10-07 | Lesaffre & Cie | Nouvelles compositions destinees a la prevention et/ou au traitement du diabete |
| KR101420355B1 (ko) * | 2012-03-13 | 2014-07-16 | 농림수산식품기술기획평가원 | 신규한 페디오코커스 에시디락티시 ｍ７６ 균주 및 이로부터 생산되는 세포외다당류 |
| MA41020A (fr) * | 2014-11-25 | 2017-10-03 | Evelo Biosciences Inc | Compositions probiotiques et prébiotiques, et leurs procédés d'utilisation pour la modulation du microbiome |
| US10195237B2 (en) * | 2015-03-16 | 2019-02-05 | Imagilin Technology Llc | Compositions and methods for treating inflammatory related diseases or conditions using Pediococcus acidilactici probiotics |
| CN107028985A (zh) * | 2016-02-04 | 2017-08-11 | 深圳华大基因研究院 | 厚壁菌类益生菌在预防和/或治疗糖尿病及其相关疾病中的应用 |
-
2020
- 2020-12-18 HU HUE20845776A patent/HUE065458T2/hu unknown
- 2020-12-18 EP EP20845776.2A patent/EP4076484B1/en active Active
- 2020-12-18 HR HRP20240251TT patent/HRP20240251T1/hr unknown
- 2020-12-18 WO PCT/EP2020/087284 patent/WO2021123355A1/en not_active Ceased
- 2020-12-18 EP EP23207857.6A patent/EP4327815A3/en active Pending
- 2020-12-18 US US17/787,270 patent/US20230038352A1/en active Pending
- 2020-12-18 ES ES20845776T patent/ES2971942T3/es active Active
Also Published As
| Publication number | Publication date |
|---|---|
| HUE065458T2 (hu) | 2024-05-28 |
| US20230038352A1 (en) | 2023-02-09 |
| EP4076484C0 (en) | 2023-11-29 |
| ES2971942T3 (es) | 2024-06-10 |
| EP4327815A3 (en) | 2024-05-22 |
| WO2021123355A1 (en) | 2021-06-24 |
| EP4076484B1 (en) | 2023-11-29 |
| EP4076484A1 (en) | 2022-10-26 |
| EP4327815A2 (en) | 2024-02-28 |
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