HRP20170972T1 - Kombinacijska terapija afukoziliranog cd20-protutijela s bendamustinom - Google Patents

Kombinacijska terapija afukoziliranog cd20-protutijela s bendamustinom

Info

Publication number: HRP20170972T1
Authority: HR; Croatia
Prior art keywords: afucosilated; bendamustine; antibody; combination therapy; therapy
Prior art date: 2009-08-14

Application number

HRP20170972TT

Other languages

English (en)

Inventor

Frank Herting

Christian Klein

Original Assignee

Roche Glycart Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2009-08-14

Filing date

2010-08-12

Publication date

2017-09-22

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41351729&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP20170972(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2010-08-12 Application filed by Roche Glycart Ag filed Critical Roche Glycart Ag

2017-09-22 Publication of HRP20170972T1 publication Critical patent/HRP20170972T1/hr

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2887—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
- C07K2317/41—Glycosylation, sialylation, or fucosylation

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Immunology (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Microbiology (AREA)
Mycology (AREA)
Biomedical Technology (AREA)
Oncology (AREA)
Genetics & Genomics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Peptides Or Proteins (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

HRP20170972TT 2009-08-14 2010-08-12 Kombinacijska terapija afukoziliranog cd20-protutijela s bendamustinom HRP20170972T1 (hr)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
EP09010489		2009-08-14
PCT/EP2010/004939 WO2011018224A1 (en)	2009-08-14	2010-08-12	Combination therapy of an afucosylated cd20 antibody with bendamustine
EP10747168.2A EP2464382B1 (en)	2009-08-14	2010-08-12	Combination therapy of an afucosylated cd20 antibody with bendamustine

Publications (1)

Publication Number	Publication Date
HRP20170972T1 true HRP20170972T1 (hr)	2017-09-22

Family

ID=41351729

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HRP20170972TT HRP20170972T1 (hr)	2009-08-14	2010-08-12	Kombinacijska terapija afukoziliranog cd20-protutijela s bendamustinom

Country Status (34)

Country	Link
US (4)	US20110165151A1 (hr)
EP (1)	EP2464382B1 (hr)
JP (3)	JP5646626B2 (hr)
KR (1)	KR101425736B1 (hr)
CN (2)	CN107261138A (hr)
AR (1)	AR077866A1 (hr)
AU (1)	AU2010281866B2 (hr)
CA (1)	CA2769674C (hr)
CL (1)	CL2012000391A1 (hr)
CR (1)	CR20120036A (hr)
CY (2)	CY1119251T1 (hr)
DK (1)	DK2464382T3 (hr)
ES (1)	ES2630158T3 (hr)
HK (1)	HK1245145A1 (hr)
HR (1)	HRP20170972T1 (hr)
HU (2)	HUE033531T2 (hr)
IL (1)	IL217753A (hr)
LT (2)	LT2464382T (hr)
LU (1)	LUC00045I2 (hr)
MA (1)	MA33469B1 (hr)
MX (2)	MX355849B (hr)
MY (1)	MY163003A (hr)
NO (1)	NO2017054I1 (hr)
NZ (1)	NZ597666A (hr)
PL (1)	PL2464382T3 (hr)
PT (1)	PT2464382T (hr)
RS (1)	RS56146B1 (hr)
SG (1)	SG178324A1 (hr)
SI (1)	SI2464382T1 (hr)
SM (1)	SMT201700329T1 (hr)
TW (1)	TWI409079B (hr)
UA (1)	UA110096C2 (hr)
WO (1)	WO2011018224A1 (hr)
ZA (1)	ZA201200830B (hr)

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EP2247620B1 (en)	2008-01-31	2016-05-18	Genentech, Inc.	Anti-cd79b antibodies and immunoconjugates and methods of use
LT2578585T (lt)	2010-05-31	2016-10-10	Ono Pharmaceutical Co., Ltd.	Purinono darinys kaip btk kinazės inhibitorius
FR2976811A1 (fr) *	2011-06-22	2012-12-28	Lfb Biotechnologies	Utilisation d'un anticorps anti-cd20 a haute adcc pour le traitement de la maladie de waldenstrom
MX354479B (es) *	2011-08-16	2018-03-07	Morphosys Ag	Terapia de combinación con un anticuerpo anti-cd19 y una mostaza de nitrógeno.
HUE058855T2 (hu) *	2011-08-16	2022-09-28	Morphosys Ag	Kombinációs terápia, CD19 elleni ellenanyag és purinanalóg alkalmazásával
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EP2786996B1 (en)	2011-11-29	2016-09-14	ONO Pharmaceutical Co., Ltd.	Purinone derivative hydrochloride
CN103375132A (zh) *	2012-04-24	2013-10-30	长江大学	井下旋转冲击式钻井工具
EP2762496A1 (en)	2013-02-05	2014-08-06	EngMab AG	Method for the selection of antibodies against BCMA
CN104968682A (zh)	2013-02-05	2015-10-07	英格玛布股份公司	针对CD3ε和BCMA的双特异性抗体
US20160101199A1 (en)	2013-06-07	2016-04-14	Nordic Nanovector As	Method for upregulating antigen expression
EP3122360B1 (en)	2014-03-25	2020-06-17	ONO Pharmaceutical Co., Ltd.	Prophylactic agent and/or therapeutic agent for diffuse large b-cell lymphoma
PT3262071T (pt)	2014-09-23	2020-06-16	H Hoffnabb La Roche Ag	Métodos de utilização de imunoconjugados anti-cd79b
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SMT202000139T1 (it)	2015-08-03	2020-05-08	Engmab Sarl	Anticorpi monoclonali contro l'antigene umano di maturazione delle cellule b (bcma)
EP3257866A1 (en) *	2016-06-17	2017-12-20	Academisch Medisch Centrum	Modified anti-tnf antibody and use thereof in the treatment of ibd
BR112019008426A2 (pt)	2016-11-02	2019-09-03	Engmab Sarl	anticorpo biespecífico contra bcma e cd3 e um fármaco imunológico para uso combinado no tratamento de mieloma múltiplo
CA3046489A1 (en)	2016-12-07	2018-06-14	Progenity Inc.	Gastrointestinal tract detection methods, devices and systems
EP4108183A1 (en)	2017-03-30	2022-12-28	Biora Therapeutics, Inc.	Treatment of a disease of the gastrointestinal tract with an immune modulatory agent released using an ingestible device
IL278853B2 (en)	2018-05-23	2025-06-01	Celgene Corp	Antiproliferative compounds and a bispecific antibody against BCMA and CD3 for combined use
US12227565B2 (en)	2018-06-20	2025-02-18	Biora Therapeutics, Inc.	Method of formulating a pharmaceutical composition comprising administering an immune modulator to the small intestine
WO2019246312A1 (en)	2018-06-20	2019-12-26	Progenity, Inc.	Treatment of a disease of the gastrointestinal tract with an immunomodulator
AU2019383976B2 (en)	2018-11-19	2025-07-03	Bt Bidco, Inc.	Methods and devices for treating a disease with biotherapeutics
JP7287048B2 (ja)	2019-03-27	2023-06-06	セイコーエプソン株式会社	ロボット
EP3870261B1 (en)	2019-12-13	2024-01-31	Biora Therapeutics, Inc.	Ingestible device for delivery of therapeutic agent to the gastrointestinal tract

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2010
- 2010-08-11 TW TW099126813A patent/TWI409079B/zh active
- 2010-08-12 CN CN201710422477.2A patent/CN107261138A/zh active Pending
- 2010-08-12 PT PT107471682T patent/PT2464382T/pt unknown
- 2010-08-12 PL PL10747168T patent/PL2464382T3/pl unknown
- 2010-08-12 CA CA2769674A patent/CA2769674C/en active Active
- 2010-08-12 AR ARP100102968A patent/AR077866A1/es unknown
- 2010-08-12 MX MX2014015198A patent/MX355849B/es unknown
- 2010-08-12 DK DK10747168.2T patent/DK2464382T3/en active
- 2010-08-12 ES ES10747168.2T patent/ES2630158T3/es active Active
- 2010-08-12 SM SM20170329T patent/SMT201700329T1/it unknown
- 2010-08-12 NZ NZ597666A patent/NZ597666A/xx unknown
- 2010-08-12 WO PCT/EP2010/004939 patent/WO2011018224A1/en active Application Filing
- 2010-08-12 SG SG2012008843A patent/SG178324A1/en unknown
- 2010-08-12 JP JP2012524146A patent/JP5646626B2/ja active Active
- 2010-08-12 SI SI201031491T patent/SI2464382T1/sl unknown
- 2010-08-12 HU HUE10747168A patent/HUE033531T2/hu unknown
- 2010-08-12 KR KR1020127006528A patent/KR101425736B1/ko active Active
- 2010-08-12 HR HRP20170972TT patent/HRP20170972T1/hr unknown
- 2010-08-12 MY MYPI2012000606A patent/MY163003A/en unknown
- 2010-08-12 MA MA34585A patent/MA33469B1/fr unknown
- 2010-08-12 CN CN201080035971XA patent/CN102596245A/zh active Pending
- 2010-08-12 LT LTEP10747168.2T patent/LT2464382T/lt unknown
- 2010-08-12 EP EP10747168.2A patent/EP2464382B1/en active Active
- 2010-08-12 MX MX2012001782A patent/MX2012001782A/es active IP Right Grant
- 2010-08-12 AU AU2010281866A patent/AU2010281866B2/en active Active
- 2010-08-12 RS RS20170647A patent/RS56146B1/sr unknown
- 2010-08-13 US US12/855,827 patent/US20110165151A1/en not_active Abandoned
- 2010-12-08 UA UAA201202678A patent/UA110096C2/ru unknown
2012
- 2012-01-19 CR CR20120036A patent/CR20120036A/es unknown
- 2012-01-26 IL IL217753A patent/IL217753A/en active IP Right Grant
- 2012-02-02 ZA ZA2012/00830A patent/ZA201200830B/en unknown
- 2012-02-08 US US13/368,465 patent/US20120315268A1/en not_active Abandoned
- 2012-02-14 CL CL2012000391A patent/CL2012000391A1/es unknown
2013
- 2013-01-18 HK HK18104879.8A patent/HK1245145A1/zh unknown
- 2013-03-06 US US13/787,532 patent/US20140044705A1/en not_active Abandoned
2014
- 2014-05-08 US US14/273,148 patent/US20160166688A9/en not_active Abandoned
- 2014-11-04 JP JP2014224221A patent/JP5963013B2/ja active Active
2016
- 2016-06-15 JP JP2016118739A patent/JP2016222673A/ja active Pending
2017
- 2017-07-03 CY CY20171100706T patent/CY1119251T1/el unknown
- 2017-10-26 LU LU00045C patent/LUC00045I2/fr unknown
- 2017-10-26 NO NO2017054C patent/NO2017054I1/no unknown
- 2017-10-26 CY CY2017034C patent/CY2017034I1/el unknown
- 2017-10-27 HU HUS1700041C patent/HUS000498I2/hu unknown
- 2017-10-31 LT LTPA2017035C patent/LTPA2017035I1/lt unknown

Also Published As

Publication number	Publication date
TW201110980A (en)	2011-04-01
LTPA2017035I1 (lt)	2017-11-27
LUC00045I1 (hr)	2017-11-03
JP5963013B2 (ja)	2016-08-03
SI2464382T1 (sl)	2017-08-31
EP2464382A1 (en)	2012-06-20
NO2017054I1 (no)	2017-10-26
LUC00045I2 (hr)	2018-02-26
HUS1700041I1 (hu)	2017-11-28
BR112012002855A2 (pt)	2016-11-01
NZ597666A (en)	2013-10-25
CR20120036A (es)	2012-04-18
RU2012109445A (ru)	2013-09-27
CY2017034I2 (el)	2018-02-14
AR077866A1 (es)	2011-09-28
TWI409079B (zh)	2013-09-21
JP2016222673A (ja)	2016-12-28
US20150093376A1 (en)	2015-04-02
JP5646626B2 (ja)	2014-12-24
CL2012000391A1 (es)	2012-08-24
HUE033531T2 (hu)	2021-12-28
HK1245145A1 (zh)	2018-08-24
SG178324A1 (en)	2012-03-29
MX355849B (es)	2018-05-02
LT2464382T (lt)	2017-07-25
ES2630158T3 (es)	2017-08-18
AU2010281866A1 (en)	2012-02-02
PL2464382T3 (pl)	2017-09-29
CY1119251T1 (el)	2018-02-14
JP2013501740A (ja)	2013-01-17
MX2012001782A (es)	2012-04-19
MY163003A (en)	2017-07-31
JP2015071611A (ja)	2015-04-16
US20110165151A1 (en)	2011-07-07
US20140044705A1 (en)	2014-02-13
US20160166688A9 (en)	2016-06-16
RS56146B1 (sr)	2017-11-30
ZA201200830B (en)	2012-10-31
PT2464382T (pt)	2017-06-30
CN102596245A (zh)	2012-07-18
IL217753A0 (en)	2012-03-29
HUS000498I2 (hu)	2021-03-29
CA2769674A1 (en)	2011-02-17
MA33469B1 (fr)	2012-07-03
AU2010281866B2 (en)	2016-05-12
EP2464382B1 (en)	2017-05-03
DK2464382T3 (en)	2017-07-17
CY2017034I1 (el)	2018-02-14
KR101425736B1 (ko)	2014-08-01
UA110096C2 (uk)	2015-11-25
KR20120054068A (ko)	2012-05-29
CN107261138A (zh)	2017-10-20
CA2769674C (en)	2018-01-23
WO2011018224A1 (en)	2011-02-17
IL217753A (en)	2016-10-31
US20120315268A1 (en)	2012-12-13
SMT201700329T1 (it)	2017-09-07

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