HK63792A - 6-substituted-4-dialkylamino-tetrahydrobenz(c,d)indoles - Google Patents

6-substituted-4-dialkylamino-tetrahydrobenz(c,d)indoles

Info

Publication number: HK63792A
Authority: HK; Hong Kong
Prior art keywords: tetrahydrobenz; indoles; dialkylamino; substituted
Prior art date: 1984-02-06

Application number

HK637/92A

Other languages

English (en)

Inventor

Michael Edward Flaugh

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-02-06

Filing date

1992-08-20

Publication date

1992-08-28

1992-08-20 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1992-08-28 Publication of HK63792A publication Critical patent/HK63792A/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/90—Benzo [c, d] indoles; Hydrogenated benzo [c, d] indoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Neurosurgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Neurology (AREA)
Pharmacology & Pharmacy (AREA)
Biomedical Technology (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Psychiatry (AREA)
Obesity (AREA)
Pain & Pain Management (AREA)
Child & Adolescent Psychology (AREA)
Diabetes (AREA)
Hematology (AREA)
Addiction (AREA)
Hospice & Palliative Care (AREA)
Indole Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

HK637/92A 1984-02-06 1992-08-20 6-substituted-4-dialkylamino-tetrahydrobenz(c,d)indoles HK63792A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US57709684A	1984-02-06	1984-02-06

Publications (1)

Publication Number	Publication Date
HK63792A true HK63792A (en)	1992-08-28

Family

ID=24307259

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HK637/92A HK63792A (en)	1984-02-06	1992-08-20	6-substituted-4-dialkylamino-tetrahydrobenz(c,d)indoles

Country Status (24)

Country	Link
EP (1)	EP0153083B1 (es)
JP (2)	JPH0699388B2 (es)
KR (1)	KR860001892B1 (es)
AR (1)	AR240641A1 (es)
AT (1)	ATE53021T1 (es)
AU (1)	AU572258B2 (es)
CA (1)	CA1291484C (es)
CY (1)	CY1657A (es)
DE (1)	DE3577848D1 (es)
DK (1)	DK167572B1 (es)
ES (2)	ES8605236A1 (es)
GR (1)	GR850313B (es)
HK (1)	HK63792A (es)
HU (1)	HU193941B (es)
IE (1)	IE57916B1 (es)
IL (1)	IL74222A (es)
MY (1)	MY102763A (es)
NZ (1)	NZ211031A (es)
PH (1)	PH20490A (es)
PT (1)	PT79925B (es)
SG (1)	SG66992G (es)
SU (1)	SU1375128A3 (es)
UA (1)	UA5954A1 (es)
ZA (1)	ZA85916B (es)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3346573A1 (de) *	1983-12-23	1985-07-04	Troponwerke GmbH & Co KG, 5000 Köln	1,3,4,5-tetrahydrobenz(c,d)indole, ein verfahren zu ihrer herstellung und ihre verwendung
CA1266482A1 (en) *	1984-05-24	1990-03-06	Carl Kaiser	6-oxygenated-1,3,4,5-tetrahydrobenz(cd)indol-4-amines
DE3525564A1 (de) *	1985-07-15	1987-02-05	Schering Ag	Tricyclische verbindungen mit indolstruktur, verfahren zu ihrer herstellung und deren verwendung als arzneimittel
US4745126A (en) *	1987-03-12	1988-05-17	Eli Lilly And Company	Method of treating anxiety with tetrahydrobenz[c,d]indole-6-carboxamides
DE3809155A1 (de) *	1988-03-18	1989-09-28	Bayer Ag	1,3,4,5-tetrahydrobenz-(c,d)-indole
US4999382A (en) *	1988-10-26	1991-03-12	Massachusetts Institute Of Technology	Compositions for treating tobacco withdrawal symptoms and methods for their use
US5204340A (en) *	1989-04-11	1993-04-20	Eli Lilly And Company	Tetrahydrobenz(c,d)indole serotonin agonists
US5273975A (en) *	1989-06-09	1993-12-28	The Upjohn Company	Heterocyclic amines having central nervous system activity
US5039820A (en) *	1990-02-26	1991-08-13	Eli Lilly And Company	4-amino-6-iodo-hexahydrobenz(cd)indoles
US5302612A (en) *	1990-02-26	1994-04-12	Eli Lilly And Company	6-substituted-hexahydrobenz[cd]indoles
IL97308A (en) *	1990-02-26	1996-10-31	Lilly Co Eli	6-Substituted-hexahydrobenz (cd) indoles process for their preparation and pharmaceutical compositions containing them
IL97309A (en) *	1990-02-26	1996-11-14	Lilly Co Eli	Intermediates for hexahydrobenz Úcd¾ indoles and process for the preparation of pure enantiomers thereof
US5258379A (en) *	1990-05-04	1993-11-02	Eli Lilly And Company	Method of inhibiting gastric acid secretion with n-arylpiperazines
US5340838A (en) *	1990-05-04	1994-08-23	Eli Lilly And Company	Method of inhibiting gastric acid secretion with 2-phenylcyclopropylamines
US5096908A (en) *	1990-05-04	1992-03-17	Eli Lilly And Company	Method of inhibiting gastric acid secretion
US5229410A (en) *	1990-08-15	1993-07-20	Eli Lilly And Company	6-substituted-hexahydrobenz[cd]indoles
US5229409A (en) *	1990-08-15	1993-07-20	Eli Lilly And Company	6-substituted-tetrahydrobenz[cd]indoles
US5364856A (en) *	1991-03-28	1994-11-15	Eli Lilly And Company	6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz[CD]indoles
US5244912A (en) *	1991-03-28	1993-09-14	Eli Lilly And Company	6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz(cd)indoles and pharmaceutical use thereof
US5347013A (en) *	1991-03-28	1994-09-13	Eli Lilly And Company	6-heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz[cd]indoles
US5244911A (en) *	1991-03-28	1993-09-14	Eli Lilly And Company	6-heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz(cd)indoles and pharmaceutical use thereof
US5656653A (en) *	1991-03-28	1997-08-12	Eli Lilly And Company	6-heterocyclic-4-amino-1,2,2A,3,4,5-hexahydrobenz[cd]indoles
CA2166700C (en)	1993-07-27	2000-04-18	Arthur G. Romero	Heterocyclic amines having central nervous system activity
US5385928A (en) *	1994-05-18	1995-01-31	Eli Lilly And Company	Tetrahydrobenz [CD] indazoles, compositions and use
FR2732964B1 (fr) *	1995-04-14	1997-05-16	Adir	Nouveaux amides tricycliques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
US6242473B1 (en) *	1999-01-08	2001-06-05	Maxim Pharmaceuticals, Inc.	Treatment and prevention of reactive oxygen metabolite-mediated cellular damage
US7074927B2 (en)	1999-05-13	2006-07-11	Pharmacia & Upjohn Company	Heterocyclic amines having central nervous system activity
TW200732302A (en) *	2005-12-13	2007-09-01	Daicel Chem	Indoline derivative

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3194811A (en) *	1963-09-05	1965-07-13	Merck & Co Inc	Aroyl-benzindolyl acids
US4282240A (en) *	1979-11-23	1981-08-04	Merck & Co., Inc.	Amino substituted tetrahydrobenzindoles
DE3346573A1 (de) *	1983-12-23	1985-07-04	Troponwerke GmbH & Co KG, 5000 Köln	1,3,4,5-tetrahydrobenz(c,d)indole, ein verfahren zu ihrer herstellung und ihre verwendung
CA1266482A1 (en) *	1984-05-24	1990-03-06	Carl Kaiser	6-oxygenated-1,3,4,5-tetrahydrobenz(cd)indol-4-amines

1985
- 1985-02-03 IL IL74222A patent/IL74222A/xx not_active IP Right Cessation
- 1985-02-04 PH PH31815A patent/PH20490A/en unknown
- 1985-02-04 AU AU38419/85A patent/AU572258B2/en not_active Ceased
- 1985-02-04 SU SU853856855A patent/SU1375128A3/ru active
- 1985-02-04 IE IE263/85A patent/IE57916B1/en not_active IP Right Cessation
- 1985-02-04 GR GR850313A patent/GR850313B/el unknown
- 1985-02-04 UA UA3856855A patent/UA5954A1/uk unknown
- 1985-02-04 HU HU85413A patent/HU193941B/hu not_active IP Right Cessation
- 1985-02-04 NZ NZ211031A patent/NZ211031A/xx unknown
- 1985-02-04 DK DK048785A patent/DK167572B1/da not_active IP Right Cessation
- 1985-02-04 PT PT79925A patent/PT79925B/pt not_active IP Right Cessation
- 1985-02-05 KR KR1019850000715A patent/KR860001892B1/ko not_active IP Right Cessation
- 1985-02-05 JP JP60021590A patent/JPH0699388B2/ja not_active Expired - Lifetime
- 1985-02-05 ES ES540151A patent/ES8605236A1/es not_active Expired
- 1985-02-05 CA CA000473579A patent/CA1291484C/en not_active Expired - Lifetime
- 1985-02-05 AR AR29941385A patent/AR240641A1/es active
- 1985-02-06 AT AT85300779T patent/ATE53021T1/de not_active IP Right Cessation
- 1985-02-06 EP EP85300779A patent/EP0153083B1/en not_active Expired - Lifetime
- 1985-02-06 ZA ZA85916A patent/ZA85916B/xx unknown
- 1985-02-06 DE DE8585300779T patent/DE3577848D1/de not_active Expired - Lifetime
- 1985-11-15 ES ES548942A patent/ES8704894A1/es not_active Expired
1987
- 1987-09-22 MY MYPI87001863A patent/MY102763A/en unknown
1992
- 1992-07-01 SG SG669/92A patent/SG66992G/en unknown
- 1992-08-20 HK HK637/92A patent/HK63792A/xx not_active IP Right Cessation
1993
- 1993-05-14 CY CY1657A patent/CY1657A/xx unknown
- 1993-12-15 JP JP5315469A patent/JPH0745470B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
HUT37121A (en)	1985-11-28
SU1375128A3 (ru)	1988-02-15
KR860001892B1 (ko)	1986-10-24
UA5954A1 (uk)	1994-12-29
ZA85916B (en)	1986-09-24
IE57916B1 (en)	1993-05-19
ATE53021T1 (de)	1990-06-15
IL74222A0 (en)	1985-05-31
DK48785D0 (da)	1985-02-04
IL74222A (en)	1988-07-31
JPS60208959A (ja)	1985-10-21
EP0153083A2 (en)	1985-08-28
AU572258B2 (en)	1988-05-05
MY102763A (en)	1992-10-31
PT79925A (en)	1985-03-01
AR240641A1 (es)	1990-07-31
JPH0745470B2 (ja)	1995-05-17
NZ211031A (en)	1989-08-29
CY1657A (en)	1993-05-14
DK48785A (da)	1985-09-03
JPH0699388B2 (ja)	1994-12-07
EP0153083B1 (en)	1990-05-23
PH20490A (en)	1987-01-21
ES540151A0 (es)	1986-03-16
IE850263L (en)	1985-08-06
GR850313B (es)	1985-06-05
DK167572B1 (da)	1993-11-22
ES8704894A1 (es)	1987-04-16
CA1291484C (en)	1991-10-29
DE3577848D1 (de)	1990-06-28
AU3841985A (en)	1985-08-15
ES548942A0 (es)	1987-04-16
KR850005825A (ko)	1985-09-26
PT79925B (en)	1987-02-05
EP0153083A3 (en)	1987-01-14
SG66992G (en)	1992-09-04
JPH06279406A (ja)	1994-10-04
ES8605236A1 (es)	1986-03-16
HU193941B (en)	1987-12-28

Publication	Publication Date	Title
EP0153083A3 (en)	1987-01-14	6-substituted-4-dialkylaminotetrahydrobenz(c,d)indoles
GB2168347B (en)	1988-02-03	Indoles
CS420285A1 (en)	1987-08-13	Zpusob vyroby antikorozniho prostredku oceli, predevsim ocelove vyztuze
CS850384A1 (en)	1985-09-17	Zpusob upravy pecnich komor, zejmena koksovacich komor
CS32884A1 (en)	1986-12-18	Bezkontaktni zarazka, zejmena viceproslupniho tkaciho stroje
CS916084A1 (en)	1985-08-15	Konektorova privodka,zejmena elektromagnetu
CS609384A1 (en)	1985-08-15	Zpusob lepeni dvou soucasti, zvlaste optickych prvku
CS922284A1 (en)	1985-08-15	Davkovacie zariadenie suciastok, najmae integrovanych obvodov
CS209384A1 (en)	1985-05-15	Vratny dopravnik, najmae tabliet
CS209084A1 (en)	1985-05-15	Priamociary dopravnik, najmae tabliet
CS194684A1 (en)	1985-05-15	Primociary vratny dopravnik, najmae tabliet
CS1021684A1 (en)	1985-08-15	Lozny prostor dopravnich prostredku, zvlaste skrinovych ucelovych vozidel
CS648584A1 (en)	1985-09-17	Sedadlo, zvlaste operak sedadla motorovych vozidel
CS778584A1 (en)	1985-09-17	Odpruzeni napravy,zvlaste pevne napravy vozidel
CS43284A1 (en)	1987-01-15	Pochudna, abrazi odolavajcici hydroizolacni hmota
CS866784A1 (en)	1985-08-15	Bezprevodovy pohon vrtaci hlavy, zejmena plnoprofiloveho raziciho stroje
CS190684A1 (en)	1985-08-15	Stojan obrabeciho stroje, zejmena svisleho soustruhu
CS55384A1 (en)	1985-08-15	Viceucelove nosne zarizeni, zejmena bezkostroveho ruksaku
CS922184A1 (en)	1985-07-16	Peciatkovaci mechanizmus suciastok, najmae integrovanych obvodov
CS320484A1 (en)	1985-05-15	Pruchodka, zejmena stresni vtok
CS969984A1 (en)	1985-08-15	Hridelova ucpavka tociveho stroje, zejmena turbokompresoru
IE842146L (en)	1985-03-07	16-fluoro-16,17-didehydro-prostanoids
IE843143L (en)	1985-06-09	Thiolane-2,4-dione-3-carboxamides
CS99184A1 (en)	1986-11-13	Sposob kontinualnej pripravy vodnych roztokov alebo suspenzii chlornanu sodneho, draselneho alebo vapenateho
CS347484A1 (en)	1985-08-15	Vysokoteplotni ucpavka, zejmena kovovych rekuperatoru

Legal Events

Date	Code	Title	Description
2004-12-15	PC	Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)