HK128894A - Novel vitamin d analogues - Google Patents

Novel vitamin d analogues

Info

Publication number: HK128894A
Authority: HK; Hong Kong
Prior art keywords: formula; compounds; groups; diseases; present
Prior art date: 1989-02-23

Application number

HK128894A

Other languages

English (en)

Inventor

Martin John Calverley

Kai Hansen

Lise Binderup

Original Assignee

Leo Pharm Prod Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-02-23

Filing date

1994-11-17

Publication date

1994-11-25

1994-11-17 Application filed by Leo Pharm Prod Ltd filed Critical Leo Pharm Prod Ltd

1994-11-25 Publication of HK128894A publication Critical patent/HK128894A/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Diabetes (AREA)
Emergency Medicine (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Immunology (AREA)
Endocrinology (AREA)
Hematology (AREA)
Obesity (AREA)
Pulmonology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

HK128894A 1989-02-23 1994-11-17 Novel vitamin d analogues HK128894A (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GB898904154A GB8904154D0 (en)	1989-02-23	1989-02-23	Chemical compounds
PCT/DK1990/000036 WO1990009991A1 (en)	1989-02-23	1990-02-13	Novel vitamin d analogues
SG131794A SG131794G (en)	1989-02-23	1994-09-12	Novel vitamin D analogues

Publications (1)

Publication Number	Publication Date
HK128894A true HK128894A (en)	1994-11-25

Family

ID=26295003

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HK128894A HK128894A (en)	1989-02-23	1994-11-17	Novel vitamin d analogues

Country Status (22)

Country	Link
EP (1)	EP0460032B1 (ko)
JP (1)	JP2807083B2 (ko)
KR (1)	KR0163194B1 (ko)
AT (1)	ATE104957T1 (ko)
AU (1)	AU627001B2 (ko)
CA (1)	CA2044280C (ko)
DE (1)	DE69008517T2 (ko)
DK (1)	DK0460032T3 (ko)
ES (1)	ES2055905T3 (ko)
FI (1)	FI92929C (ko)
GB (1)	GB8904154D0 (ko)
HK (1)	HK128894A (ko)
HU (1)	HU211025B (ko)
IE (1)	IE63123B1 (ko)
LT (1)	LT3983B (ko)
LV (1)	LV10428B (ko)
NO (1)	NO178065C (ko)
PT (1)	PT93232B (ko)
RO (1)	RO109939B1 (ko)
RU (1)	RU2037484C1 (ko)
SG (1)	SG131794G (ko)
WO (1)	WO1990009991A1 (ko)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8904153D0 (en) *	1989-02-23	1989-04-05	Leo Pharm Prod Ltd	Chemical compounds
DE4011682A1 (de) *	1990-04-06	1991-10-10	Schering Ag	24-oxa-derivate in der vitamin d-reihe
GB9015774D0 (en) *	1990-07-18	1990-09-05	Leo Pharm Prod Ltd	Novel treatment
US5486509A (en) *	1991-06-28	1996-01-23	University Of Miami	Method of preventing and treating chemotherapy-induced alopecia
AU666563B2 (en) *	1992-08-07	1996-02-15	Wisconsin Alumni Research Foundation	Preparation of 19-nor-vitamin D compounds
GB9220272D0 (en) *	1992-09-25	1992-11-11	Leo Pharm Prod Ltd	Chemical compounds
GB9220439D0 (en) *	1992-09-28	1992-11-11	Leo Pharm Prod Ltd	Chemical compounds
US5449668A (en) *	1993-06-04	1995-09-12	Duphar International Research B.V.	Vitamin D compounds and method of preparing these compounds
US6316642B1 (en)	1997-03-17	2001-11-13	Wisconsin Alumni Research Foundation	26,27-Homologated-20-EPI-2alkyl-19-nor-vitamin D compounds
US6392071B1 (en)	1997-03-17	2002-05-21	Wisconsin Alumni: Research Foundation	26,27-homologated-20-EPI-2-alkylidene-19-nor-vitamin D compounds
US5945410A (en)	1997-03-17	1999-08-31	Wisconsin Alumni Research Foundation	2-alkyl-19-nor-vitamin D compounds
US6306844B1 (en)	1997-03-17	2001-10-23	Wisconsin Alumni Research Foundation	Use of 2α-methyl-19-nor-20(S)-1α, 25-dihydroxyvitamin D3 to increase bone strength
US5939406A (en)	1997-07-21	1999-08-17	Wisconsin Alumni Research Foundation	18-substituted-19-nor-vitamin D compounds
US6359152B2 (en)	1997-07-21	2002-03-19	Wisconsin Alumni Research Foundation	18-substituted-19-nor-vitamin D compounds
US5962707A (en) *	1998-08-18	1999-10-05	Wisconsin Alumni Research Foundation	19-nor-vitamin D3 compounds with calcemic activity
US7074777B2 (en)	2000-04-19	2006-07-11	Chugai Seiyaku Kabushiki Kaisha	Vitamin D derivatives
US20030018017A1 (en) *	2001-01-25	2003-01-23	Deluca Hector F.	Method of treatment of type I diabetes
US20060293291A1 (en)	2003-04-10	2006-12-28	Deluca Hector F	2-Propylidene-19-nor-vitamin d compounds
US6894037B2 (en)	2003-07-03	2005-05-17	Wisconsin Alumni Research Foundation	2-methylene-19-nor-20(S)-25-methyl-1α-hydroxycalciferol and its uses
US7713951B2 (en)	2004-04-09	2010-05-11	Wisconsin Alumni Research Foundation	2-alkylidene-18,19-dinor-vitamin D compounds
US20080293647A1 (en)	2004-11-12	2008-11-27	Luciano Adorini	Combined Use Of Vitamin D Derivatives And Anti-Proliferative Agents For Treating Bladder Cancer
MX2008012701A (es)	2006-04-05	2009-01-07	Wisconsin Alumni Res Found	Compuestos de 1-alfa-hidroxi-2-(3'-hidroxipropiliden)-19-nor-vitam ina d y metodos de elaboracion y tratamiento de los mismos.
US8377913B2 (en) *	2007-11-20	2013-02-19	Abbvie Inc.	Vitamin D receptor activators and methods of making
JP5563324B2 (ja) *	2010-02-03	2014-07-30	フォーモサ・ラボラトリーズ・インコーポレーテッド	マキサカルシトール中間体およびその製造方法
WO2012122451A2 (en)	2011-03-09	2012-09-13	Teva Pharmaceutical Industries Ltd.	Polymorphs of maxacalcitol and process for the preparation of maxacalcitol
CN102796134B (zh) *	2012-08-31	2015-07-01	甘肃皓天化学科技有限公司	一种马沙骨化醇中间体的制备方法
CN103910666A (zh) *	2014-04-15	2014-07-09	湖南华腾制药有限公司	一种制备马沙骨化醇的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0078704B1 (en)	1981-11-02	1987-04-29	Research Institute For Medicine And Chemistry Inc.	Intermediates in the synthesis of vitamin d derivatives
CA1332841C (en) *	1984-11-27	1994-11-01	Noboru Kubodera	Vitamin d derivatives and process for producing the same
KR940010767B1 (ko)	1985-08-02	1994-11-11	레오 파마슈티칼스 프로덕츠 리미티드 에이/에스(레벤스 케미스케 파브리크 프로덕션 사크티에셀스카브)	신규 비타민 d 동족체
WO1989010351A1 (en)	1988-04-21	1989-11-02	Leo Pharmaceutical Products Ltd. A/S (Løvens Kemis	Novel vitamin d analogues
GB8904153D0 (en) *	1989-02-23	1989-04-05	Leo Pharm Prod Ltd	Chemical compounds

1989
- 1989-02-23 GB GB898904154A patent/GB8904154D0/en active Pending
1990
- 1990-02-13 DE DE69008517T patent/DE69008517T2/de not_active Expired - Fee Related
- 1990-02-13 ES ES90903793T patent/ES2055905T3/es not_active Expired - Lifetime
- 1990-02-13 DK DK90903793.9T patent/DK0460032T3/da active
- 1990-02-13 JP JP2504126A patent/JP2807083B2/ja not_active Expired - Fee Related
- 1990-02-13 HU HU902300A patent/HU211025B/hu not_active IP Right Cessation
- 1990-02-13 KR KR1019910700655A patent/KR0163194B1/ko not_active IP Right Cessation
- 1990-02-13 AT AT9090903793T patent/ATE104957T1/de not_active IP Right Cessation
- 1990-02-13 CA CA002044280A patent/CA2044280C/en not_active Expired - Fee Related
- 1990-02-13 RO RO148060A patent/RO109939B1/ro unknown
- 1990-02-13 WO PCT/DK1990/000036 patent/WO1990009991A1/en active IP Right Grant
- 1990-02-13 EP EP90903793A patent/EP0460032B1/en not_active Expired - Lifetime
- 1990-02-13 AU AU51983/90A patent/AU627001B2/en not_active Ceased
- 1990-02-22 PT PT93232A patent/PT93232B/pt not_active IP Right Cessation
1991
- 1991-06-19 IE IE42190A patent/IE63123B1/en not_active IP Right Cessation
- 1991-07-25 NO NO912902A patent/NO178065C/no not_active IP Right Cessation
- 1991-08-12 FI FI913812A patent/FI92929C/fi active
- 1991-08-22 RU SU915001741A patent/RU2037484C1/ru not_active IP Right Cessation
1993
- 1993-09-28 LV LVP-93-1106A patent/LV10428B/en unknown
- 1993-12-06 LT LTIP1536A patent/LT3983B/lt not_active IP Right Cessation
1994
- 1994-09-12 SG SG131794A patent/SG131794G/en unknown
- 1994-11-17 HK HK128894A patent/HK128894A/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
DE69008517D1 (de)	1994-06-01
EP0460032A1 (en)	1991-12-11
FI913812A0 (fi)	1991-08-12
RU2037484C1 (ru)	1995-06-19
LV10428A (lv)	1995-02-20
AU627001B2 (en)	1992-08-13
KR0163194B1 (ko)	1999-01-15
ATE104957T1 (de)	1994-05-15
NO178065B (no)	1995-10-09
HUT59664A (en)	1992-06-29
SG131794G (en)	1995-01-13
DK0460032T3 (da)	1994-06-06
NO912902D0 (no)	1991-07-25
PT93232B (pt)	1995-12-29
FI92929C (fi)	1995-01-25
CA2044280C (en)	1999-12-21
NO178065C (no)	1996-01-17
LTIP1536A (en)	1995-09-25
LT3983B (en)	1996-06-25
RO109939B1 (ro)	1995-07-28
FI92929B (fi)	1994-10-14
CA2044280A1 (en)	1990-08-24
PT93232A (pt)	1990-08-31
HU211025B (en)	1995-09-28
LV10428B (en)	1995-10-20
KR920701145A (ko)	1992-08-11
IE900421L (en)	1990-08-23
WO1990009991A1 (en)	1990-09-07
DE69008517T2 (de)	1994-08-18
GB8904154D0 (en)	1989-04-05
IE63123B1 (en)	1995-03-22
AU5198390A (en)	1990-09-26
JP2807083B2 (ja)	1998-09-30
EP0460032B1 (en)	1994-04-27
NO912902L (no)	1991-07-25
ES2055905T3 (es)	1994-09-01
JPH04503669A (ja)	1992-07-02

Publication	Publication Date	Title
SG131794G (en)	1995-01-13	Novel vitamin D analogues
ZA905094B (en)	1991-04-24	Novel vitamin d analogues
CA2078555A1 (en)	1992-02-16	Novel vitamin d analogues
HK128994A (en)	1994-11-25	Novel vitamin d analogues
NZ234216A (en)	1993-03-26	Vitamin d analogues, preparation and pharmaceutical compositions thereof
AU625886B2 (en)	1992-07-16	New oxazolopyridine derivatives, process for preparing them and pharmaceutical compositions containing them
EP0382618A3 (fr)	1991-11-13	Dérivés aminoalkoxyphényle, leur procédé de préparation ainsi que les compositions en contenant
ZA903628B (en)	1991-04-24	Novel 9alpha-hydroxy-3-oxo-4,24(25)-stigmastadien-26-oic acid derivatives,a process for preparing same and pharmaceutical compositions containing same
AU2742288A (en)	1989-06-29	Novel compound effective as cerebral insufficiency improver

Legal Events

Date	Code	Title	Description
2004-12-15	PC	Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)