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HK1249044A1 - 用於治療或預防神經退行性疾病的槍刀藥素氧化物、其衍生物、相關化合物和激動劑 - Google Patents

用於治療或預防神經退行性疾病的槍刀藥素氧化物、其衍生物、相關化合物和激動劑

Info

Publication number
HK1249044A1
HK1249044A1 HK18108865.5A HK18108865A HK1249044A1 HK 1249044 A1 HK1249044 A1 HK 1249044A1 HK 18108865 A HK18108865 A HK 18108865A HK 1249044 A1 HK1249044 A1 HK 1249044A1
Authority
HK
Hong Kong
Prior art keywords
hypoestoxide
agonists
prevention
derivatives
treatment
Prior art date
Application number
HK18108865.5A
Other languages
English (en)
Inventor
Howard Cottam
Emmanuel Ojo-Amaize
Emeka Nchekwube
Olusola Oyemade
Original Assignee
Immune Modulation Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immune Modulation Inc filed Critical Immune Modulation Inc
Publication of HK1249044A1 publication Critical patent/HK1249044A1/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/336Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having three-membered rings, e.g. oxirane, fumagillin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Psychology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
HK18108865.5A 2015-03-09 2018-07-09 用於治療或預防神經退行性疾病的槍刀藥素氧化物、其衍生物、相關化合物和激動劑 HK1249044A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562177187P 2015-03-09 2015-03-09
PCT/US2016/016294 WO2016144441A1 (en) 2015-03-09 2016-02-03 Hypoestoxide, derivatives, related compounds, and agonists thereof for treatment or prevention of neurodegenerative diseases

Publications (1)

Publication Number Publication Date
HK1249044A1 true HK1249044A1 (zh) 2018-10-26

Family

ID=56879251

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18108865.5A HK1249044A1 (zh) 2015-03-09 2018-07-09 用於治療或預防神經退行性疾病的槍刀藥素氧化物、其衍生物、相關化合物和激動劑

Country Status (8)

Country Link
US (1) US10857122B2 (zh)
EP (1) EP3267992A4 (zh)
JP (1) JP6684524B2 (zh)
CN (1) CN107530312A (zh)
AU (1) AU2016229520B2 (zh)
CA (1) CA2978869C (zh)
HK (1) HK1249044A1 (zh)
WO (1) WO2016144441A1 (zh)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107530312A (zh) 2015-03-09 2018-01-02 免疫调节公司 用于治疗或预防神经退行性疾病的枪刀药素氧化物、其衍生物、相关化合物和激动剂
PL3894857T3 (pl) * 2019-04-15 2023-01-09 Nanologica Ab Puste porowate cząstki do stosowania w leczeniu, zapobieganiu i/lub opóźnianiu degeneracyjności chorób neurodgeneracyjnych, neuronów i gleju

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5801193A (en) * 1997-04-15 1998-09-01 Immune Modulation, Inc. Compositions and methods for immunosuppressing
US6001871A (en) * 1998-01-15 1999-12-14 Immune Modulation, Inc. Hypoestoxides, derivatives and agonists thereof for use as antiviral agents
CA2310250A1 (en) * 1997-11-14 1999-05-27 August Masaru Watanabe Treatment for alzheimer's disease
DE60305727T2 (de) * 2002-10-28 2007-05-31 Paraquest, Inc., Bloomington Hypoestoxide, derivate und agonisten davon zur verwendung bei der behandlung und prophylaxe von hyperlipidämie
WO2005047860A2 (en) * 2003-11-08 2005-05-26 Elan Pharmaceuticals, Inc. Antibodies to alpha-synuclein
US20060253100A1 (en) 2004-10-22 2006-11-09 Medtronic, Inc. Systems and Methods to Treat Pain Locally
AT506535B1 (de) * 2008-02-22 2010-04-15 Affiris Forschungs & Entwicklungs Gmbh Vaccine enthaltend alpha-synuclein-mimotope auf basis von peptiden
US8124654B2 (en) * 2008-11-11 2012-02-28 Immune Modulation, Inc. Derivatives of hypoestoxide and related compounds
WO2010065927A2 (en) 2008-12-05 2010-06-10 California Institute Of Technology Dna-damage-induced proteolysis
CN107530312A (zh) 2015-03-09 2018-01-02 免疫调节公司 用于治疗或预防神经退行性疾病的枪刀药素氧化物、其衍生物、相关化合物和激动剂

Also Published As

Publication number Publication date
AU2016229520B2 (en) 2020-10-22
CA2978869C (en) 2023-09-19
EP3267992A1 (en) 2018-01-17
JP6684524B2 (ja) 2020-04-22
CN107530312A (zh) 2018-01-02
US20180104211A1 (en) 2018-04-19
AU2016229520A1 (en) 2017-10-26
EP3267992A4 (en) 2018-12-05
US10857122B2 (en) 2020-12-08
JP2018507876A (ja) 2018-03-22
WO2016144441A1 (en) 2016-09-15
CA2978869A1 (en) 2016-09-15

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