HK1220183A1 - 吡啶基和稠合吡啶基三唑酮衍生物 - Google Patents

吡啶基和稠合吡啶基三唑酮衍生物

Info

Publication number: HK1220183A1
Authority: HK; Hong Kong
Prior art keywords: pyridinyl; fused; triazolone derivatives; derivatives; triazolone
Prior art date: 2013-03-11

Application number

HK16108174.3A

Other languages

English (en)

Inventor

David Lawson John

Sabat Mark

Scorah Nicholas

Smith Christopher

H Vu Phong

Wang Haixia

Original Assignee

Takeda Pharmaceuticals Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2013-03-11

Filing date

2016-07-12

Publication date

2017-04-28

2016-07-12 Application filed by Takeda Pharmaceuticals Co filed Critical Takeda Pharmaceuticals Co

2017-04-28 Publication of HK1220183A1 publication Critical patent/HK1220183A1/zh

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Hematology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

HK16108174.3A 2013-03-11 2016-07-12 吡啶基和稠合吡啶基三唑酮衍生物 HK1220183A1 (zh)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US201361776445P	2013-03-11	2013-03-11
PCT/US2014/022801 WO2014164558A1 (en)	2013-03-11	2014-03-10	Pyridinyl and fused pyridinyl triazolone derivatives

Publications (1)

Publication Number	Publication Date
HK1220183A1 true HK1220183A1 (zh)	2017-04-28

Family

ID=50543655

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
HK16108174.3A HK1220183A1 (zh)	2013-03-11	2016-07-12	吡啶基和稠合吡啶基三唑酮衍生物
HK18104553.1A HK1245256B (zh)	2013-03-11	2018-04-06	吡啶基和稠合吡啶基三唑酮衍生物

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
HK18104553.1A HK1245256B (zh)	2013-03-11	2018-04-06	吡啶基和稠合吡啶基三唑酮衍生物

Country Status (43)

Country	Link
US (4)	US9402841B2 (zh)
EP (2)	EP3235814B1 (zh)
JP (2)	JP6271700B2 (zh)
KR (1)	KR102300612B1 (zh)
CN (1)	CN105121427B (zh)
AP (1)	AP2015008646A0 (zh)
AR (1)	AR095198A1 (zh)
AU (1)	AU2014249248B2 (zh)
BR (1)	BR112015020264B1 (zh)
CA (1)	CA2899948C (zh)
CL (1)	CL2015002370A1 (zh)
CR (1)	CR20150470A (zh)
CY (1)	CY1119356T1 (zh)
DK (1)	DK2970202T3 (zh)
DO (1)	DOP2015000184A (zh)
EA (1)	EA028584B1 (zh)
EC (1)	ECSP15042779A (zh)
ES (2)	ES2624439T3 (zh)
GE (1)	GEP201706778B (zh)
HK (2)	HK1220183A1 (zh)
HR (1)	HRP20170622T1 (zh)
HU (1)	HUE032720T2 (zh)
IL (1)	IL240353B (zh)
JO (1)	JO3377B1 (zh)
LT (1)	LT2970202T (zh)
MA (1)	MA38391B1 (zh)
ME (1)	ME02693B (zh)
MX (1)	MX364527B (zh)
MY (1)	MY183927A (zh)
PE (1)	PE20151889A1 (zh)
PH (1)	PH12015502046B1 (zh)
PL (1)	PL2970202T3 (zh)
PT (1)	PT2970202T (zh)
RS (1)	RS55879B1 (zh)
SG (1)	SG11201506112QA (zh)
SI (1)	SI2970202T1 (zh)
SM (1)	SMT201700218T1 (zh)
TN (1)	TN2015000342A1 (zh)
TW (1)	TWI637950B (zh)
UA (1)	UA114944C2 (zh)
UY (1)	UY35376A (zh)
WO (1)	WO2014164558A1 (zh)
ZA (1)	ZA201505996B (zh)

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JP2022526713A (ja)	2019-03-21	2022-05-26	オンクセオ	がんの処置のための、キナーゼ阻害剤と組み合わせたＤｂａｉｔ分子
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JO3377B1 (ar)	2013-03-11	2019-03-13	Takeda Pharmaceuticals Co	مشتقات بيريدينيل وبيريدينيل مندمج

2014
- 2014-03-05 JO JOP/2014/0070A patent/JO3377B1/ar active
- 2014-03-10 PT PT147191308T patent/PT2970202T/pt unknown
- 2014-03-10 EP EP17152008.3A patent/EP3235814B1/en active Active
- 2014-03-10 ES ES14719130.8T patent/ES2624439T3/es active Active
- 2014-03-10 UA UAA201507597A patent/UA114944C2/uk unknown
- 2014-03-10 AR ARP140100805A patent/AR095198A1/es active IP Right Grant
- 2014-03-10 JP JP2016501072A patent/JP6271700B2/ja active Active
- 2014-03-10 HU HUE14719130A patent/HUE032720T2/en unknown
- 2014-03-10 DK DK14719130.8T patent/DK2970202T3/en active
- 2014-03-10 KR KR1020157028600A patent/KR102300612B1/ko active IP Right Grant
- 2014-03-10 AP AP2015008646A patent/AP2015008646A0/xx unknown
- 2014-03-10 SG SG11201506112QA patent/SG11201506112QA/en unknown
- 2014-03-10 MA MA38391A patent/MA38391B1/fr unknown
- 2014-03-10 SI SI201430203A patent/SI2970202T1/sl unknown
- 2014-03-10 SM SM20170218T patent/SMT201700218T1/it unknown
- 2014-03-10 AU AU2014249248A patent/AU2014249248B2/en active Active
- 2014-03-10 RS RS20170414A patent/RS55879B1/sr unknown
- 2014-03-10 GE GEAP201413953A patent/GEP201706778B/en unknown
- 2014-03-10 CN CN201480012902.5A patent/CN105121427B/zh active Active
- 2014-03-10 EA EA201591686A patent/EA028584B1/ru unknown
- 2014-03-10 PE PE2015001905A patent/PE20151889A1/es active IP Right Grant
- 2014-03-10 PL PL14719130T patent/PL2970202T3/pl unknown
- 2014-03-10 BR BR112015020264-0A patent/BR112015020264B1/pt active IP Right Grant
- 2014-03-10 CA CA2899948A patent/CA2899948C/en active Active
- 2014-03-10 EP EP14719130.8A patent/EP2970202B1/en active Active
- 2014-03-10 TW TW103108214A patent/TWI637950B/zh active
- 2014-03-10 WO PCT/US2014/022801 patent/WO2014164558A1/en active Application Filing
- 2014-03-10 UY UY0001035376A patent/UY35376A/es not_active Application Discontinuation
- 2014-03-10 MY MYPI2015703082A patent/MY183927A/en unknown
- 2014-03-10 LT LTEP14719130.8T patent/LT2970202T/lt unknown
- 2014-03-10 US US14/203,366 patent/US9402841B2/en active Active
- 2014-03-10 MX MX2015011533A patent/MX364527B/es active IP Right Grant
- 2014-03-10 ME MEP-2017-98A patent/ME02693B/me unknown
- 2014-03-10 ES ES17152008T patent/ES2714166T3/es active Active
2015
- 2015-08-04 IL IL240353A patent/IL240353B/en active IP Right Grant
- 2015-08-06 DO DO2015000184A patent/DOP2015000184A/es unknown
- 2015-08-11 TN TN2015000342A patent/TN2015000342A1/en unknown
- 2015-08-19 ZA ZA2015/05996A patent/ZA201505996B/en unknown
- 2015-08-24 CL CL2015002370A patent/CL2015002370A1/es unknown
- 2015-09-10 PH PH12015502046A patent/PH12015502046B1/en unknown
- 2015-09-10 CR CR20150470A patent/CR20150470A/es unknown
- 2015-10-08 EC ECIEPI201542779A patent/ECSP15042779A/es unknown
2016
- 2016-06-29 US US15/197,051 patent/US9801872B2/en active Active
- 2016-07-12 HK HK16108174.3A patent/HK1220183A1/zh unknown
2017
- 2017-04-20 HR HRP20170622TT patent/HRP20170622T1/hr unknown
- 2017-04-25 CY CY20171100458T patent/CY1119356T1/el unknown
- 2017-09-27 US US15/717,624 patent/US10307414B2/en active Active
- 2017-12-27 JP JP2017252294A patent/JP6462842B2/ja active Active
2018
- 2018-04-06 HK HK18104553.1A patent/HK1245256B/zh unknown
2019
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SMT201700218T1 (it)	2017-07-18
ES2714166T3 (es)	2019-05-27
EP2970202B1 (en)	2017-02-01
US9801872B2 (en)	2017-10-31
US20180015083A1 (en)	2018-01-18
RS55879B1 (sr)	2017-08-31
CA2899948C (en)	2021-11-16
JO3377B1 (ar)	2019-03-13
PT2970202T (pt)	2017-05-03
CR20150470A (es)	2016-01-11
JP2016512515A (ja)	2016-04-28
AU2014249248A1 (en)	2015-08-20
WO2014164558A1 (en)	2014-10-09
JP6462842B2 (ja)	2019-01-30
NZ710852A (en)	2020-12-18
CN105121427A (zh)	2015-12-02
SI2970202T1 (sl)	2017-07-31
DK2970202T3 (en)	2017-05-08
AR095198A1 (es)	2015-09-30
EP2970202A1 (en)	2016-01-20
US20140256734A1 (en)	2014-09-11
EP3235814A1 (en)	2017-10-25
US10307414B2 (en)	2019-06-04
JP2018076357A (ja)	2018-05-17
AU2014249248B2 (en)	2017-08-17
MX364527B (es)	2019-04-30
ECSP15042779A (es)	2017-08-31
ME02693B (me)	2017-10-20
HUE032720T2 (en)	2017-10-30
PH12015502046A1 (en)	2016-01-18
TN2015000342A1 (en)	2017-01-03
GEP201706778B (en)	2017-11-27
CA2899948A1 (en)	2014-10-09
PL2970202T3 (pl)	2017-08-31
CN105121427B (zh)	2018-04-10
PH12015502046B1 (en)	2019-01-23
US20190224190A1 (en)	2019-07-25
SG11201506112QA (en)	2015-09-29
US20160310483A1 (en)	2016-10-27
PE20151889A1 (es)	2015-12-26
TWI637950B (zh)	2018-10-11
ZA201505996B (en)	2016-11-30
MA38391A1 (fr)	2018-01-31
IL240353A0 (en)	2015-09-24
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DOP2015000184A (es)	2015-11-30
BR112015020264A2 (pt)	2017-07-18
KR20150126687A (ko)	2015-11-12
HK1245256B (zh)	2019-09-27
EA028584B1 (ru)	2017-12-29
LT2970202T (lt)	2017-06-12
KR102300612B1 (ko)	2021-09-09
CL2015002370A1 (es)	2016-03-11
IL240353B (en)	2018-11-29
HRP20170622T1 (hr)	2017-06-30
UA114944C2 (uk)	2017-08-28
UY35376A (es)	2014-10-31
MA38391B1 (fr)	2018-09-28
EP3235814B1 (en)	2018-12-12
US9402841B2 (en)	2016-08-02
BR112015020264B1 (pt)	2021-03-02
MY183927A (en)	2021-03-17

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HK1245256B (zh)	2019-09-27	吡啶基和稠合吡啶基三唑酮衍生物
HK1219651A1 (zh)	2017-04-13	吡咯並苯並二氮雜卓以及其結合物
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HK1218512A1 (zh)	2017-02-24	雜環化合物和其用途
GB201317982D0 (en)	2013-11-27	Pyrrolobenzodiazepines and conjugates thereof
GB201317981D0 (en)	2013-11-27	Pyrrolobenzodiazepines and conjugates thereof
PL2845498T3 (pl)	2018-07-31	Woreczek na tytoń
EP3004057A4 (en)	2016-11-02	HETEROCYCLIC DERIVATIVES AND THEIR USE
ZA201507657B (en)	2022-08-31	Pyridin-4-yl derivatives
HK1220363A1 (zh)	2017-05-05	雜環化合物及其用途
IL244383A0 (en)	2016-04-21	Triazolone compounds and their uses
IL245597B (en)	2020-04-30	Anti-neuroinflammatory and protective compounds in Achillea fragrantissima - implications for inflammatory and neurodegenerative diseases
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