HK1213266A1 - 具有較高碳水化合物抗原密度的疫苗及新穎皂素佐劑 - Google Patents

具有較高碳水化合物抗原密度的疫苗及新穎皂素佐劑

Info

Publication number: HK1213266A1
Authority: HK; Hong Kong
Prior art keywords: vaccines; carbohydrate antigen; antigen density; saponin adjuvant; higher carbohydrate
Prior art date: 2013-01-04

Application number

HK16101118.7A

Other languages

English (en)

Inventor

李威漢

王南絢

張忠豪

謝義簧

游丞德

王正琪

林雨新

林侑蓁

陳怡如

Original Assignee

Obi Pharma Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2013-01-04

Filing date

2016-02-01

Publication date

2016-06-30

2016-02-01 Application filed by Obi Pharma Inc filed Critical Obi Pharma Inc

2016-06-30 Publication of HK1213266A1 publication Critical patent/HK1213266A1/zh

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001169—Tumor associated carbohydrates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0016—Combination vaccines based on diphtheria-tetanus-pertussis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/256—Polyterpene radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6081—Albumin; Keyhole limpet haemocyanin [KLH]

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Organic Chemistry (AREA)
Immunology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Mycology (AREA)
Microbiology (AREA)
Molecular Biology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Genetics & Genomics (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Oncology (AREA)
Virology (AREA)
Pulmonology (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Urology & Nephrology (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Steroid Compounds (AREA)
Medicinal Preparation (AREA)

HK16101118.7A 2013-01-04 2016-02-01 具有較高碳水化合物抗原密度的疫苗及新穎皂素佐劑 HK1213266A1 (zh)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US201361748880P	2013-01-04	2013-01-04
PCT/US2014/010310 WO2014107652A2 (en)	2013-01-04	2014-01-06	Vaccines with higher carbohydrate antigen density and novel saponin adjuvant

Publications (1)

Publication Number	Publication Date
HK1213266A1 true HK1213266A1 (zh)	2016-06-30

Family

ID=51062556

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HK16101118.7A HK1213266A1 (zh)	2013-01-04	2016-02-01	具有較高碳水化合物抗原密度的疫苗及新穎皂素佐劑

Country Status (17)

Country	Link
US (2)	US10517936B2 (zh)
EP (2)	EP2941436B1 (zh)
JP (2)	JP6359561B2 (zh)
KR (2)	KR102084301B1 (zh)
CN (2)	CN105026413B (zh)
AU (2)	AU2014203977B2 (zh)
CA (2)	CA2897084C (zh)
CL (2)	CL2015001900A1 (zh)
ES (1)	ES2843509T3 (zh)
HK (1)	HK1213266A1 (zh)
IL (2)	IL239785B (zh)
PH (1)	PH12015501519A1 (zh)
RU (1)	RU2015131033A (zh)
SG (1)	SG11201505301XA (zh)
TW (2)	TWI572356B (zh)
WO (1)	WO2014107652A2 (zh)
ZA (1)	ZA201504813B (zh)

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JP6899321B2 (ja) *	2014-09-08	2021-07-07	アカデミアシニカＡｃａｄｅｍｉａＳｉｎｉｃａ	糖脂質を使用するヒトｉＮＫＴ細胞活性化
ES2797747T3 (es) *	2014-09-15	2020-12-03	Obi Pharma Inc	Composiciones de glucoconjugado inmunogénicas/terapéuticas y usos de las mismas
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WO2017041027A1 (en) *	2015-09-04	2017-03-09	Obi Pharma, Inc.	Glycan arrays and method of use
US10980894B2 (en)	2016-03-29	2021-04-20	Obi Pharma, Inc.	Antibodies, pharmaceutical compositions and methods
EP3436482A4 (en)	2016-03-29	2020-03-11	OBI Pharma, Inc.	ANTIBODIES, PHARMACEUTICAL COMPOSITIONS AND METHODS
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KR20230117482A (ko)	2016-07-27	2023-08-08	오비아이 파머 인코퍼레이티드	면역원성/치료 글리칸 조성물 및 그의 용도
US11643456B2 (en)	2016-07-29	2023-05-09	Obi Pharma, Inc.	Human antibodies, pharmaceutical compositions and methods
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TWI853822B (zh)	2018-06-27	2024-09-01	台灣浩鼎生技股份有限公司	用於糖蛋白工程的糖苷合成酶變體及其使用方法
CN114805454B (zh) *	2021-01-21	2023-07-18	中国科学院生态环境研究中心	α-半乳糖神经酰胺类化合物及其制备方法和用途
CN114259559B (zh) *	2021-12-28	2024-03-19	天津科技大学	一种含有α-GalCer内源性佐剂的合成肿瘤疫苗
CN114306586A (zh) *	2022-01-04	2022-04-12	天津科技大学	基于tf抗原和壳寡糖内源性佐剂的肿瘤疫苗、方法和应用

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2014
- 2014-01-06 CA CA2897084A patent/CA2897084C/en active Active
- 2014-01-06 EP EP14735355.1A patent/EP2941436B1/en active Active
- 2014-01-06 SG SG11201505301XA patent/SG11201505301XA/en unknown
- 2014-01-06 US US14/758,319 patent/US10517936B2/en active Active
- 2014-01-06 EP EP20187437.7A patent/EP3792272A1/en active Pending
- 2014-01-06 CN CN201480003725.4A patent/CN105026413B/zh active Active
- 2014-01-06 JP JP2015551806A patent/JP6359561B2/ja active Active
- 2014-01-06 KR KR1020177034329A patent/KR102084301B1/ko active Active
- 2014-01-06 KR KR1020157020818A patent/KR101806370B1/ko active Active
- 2014-01-06 CN CN202010234884.2A patent/CN111499679B/zh active Active
- 2014-01-06 AU AU2014203977A patent/AU2014203977B2/en active Active
- 2014-01-06 TW TW103100353A patent/TWI572356B/zh active
- 2014-01-06 CA CA3044471A patent/CA3044471C/en active Active
- 2014-01-06 ES ES14735355T patent/ES2843509T3/es active Active
- 2014-01-06 WO PCT/US2014/010310 patent/WO2014107652A2/en active Application Filing
- 2014-01-06 TW TW105141502A patent/TWI611810B/zh active
- 2014-01-06 RU RU2015131033A patent/RU2015131033A/ru not_active Application Discontinuation
2015
- 2015-07-03 CL CL2015001900A patent/CL2015001900A1/es unknown
- 2015-07-03 PH PH12015501519A patent/PH12015501519A1/en unknown
- 2015-07-03 ZA ZA2015/04813A patent/ZA201504813B/en unknown
- 2015-07-03 CL CL2015001902A patent/CL2015001902A1/es unknown
- 2015-07-05 IL IL239785A patent/IL239785B/en active IP Right Grant
2016
- 2016-02-01 HK HK16101118.7A patent/HK1213266A1/zh unknown
2017
- 2017-01-17 AU AU2017200312A patent/AU2017200312B2/en active Active
2018
- 2018-04-16 IL IL258728A patent/IL258728B/en active IP Right Grant
- 2018-06-20 JP JP2018117319A patent/JP6781204B2/ja active Active
2019
- 2019-11-01 US US16/671,395 patent/US11752204B2/en active Active

Also Published As

Publication number	Publication date
AU2017200312B2 (en)	2018-05-17
IL239785B (en)	2018-05-31
TWI611810B (zh)	2018-01-21
IL258728A (en)	2018-06-28
JP6359561B2 (ja)	2018-07-18
ES2843509T3 (es)	2021-07-19
IL239785A0 (en)	2015-08-31
EP2941436B1 (en)	2020-12-02
AU2017200312A1 (en)	2017-02-02
JP2016504385A (ja)	2016-02-12
CA3044471C (en)	2021-05-11
CL2015001900A1 (es)	2016-02-12
US11752204B2 (en)	2023-09-12
AU2014203977A1 (en)	2015-07-09
CA2897084C (en)	2019-07-16
TWI572356B (zh)	2017-03-01
RU2015131033A (ru)	2017-02-09
IL258728B (en)	2019-07-31
SG11201505301XA (en)	2015-08-28
AU2014203977B2 (en)	2016-11-17
US20150328299A1 (en)	2015-11-19
CN105026413B (zh)	2020-04-24
KR20150111941A (ko)	2015-10-06
US20200061169A1 (en)	2020-02-27
US10517936B2 (en)	2019-12-31
TW201429488A (zh)	2014-08-01
PH12015501519A1 (en)	2016-04-18
CA2897084A1 (en)	2014-07-10
EP3792272A1 (en)	2021-03-17
JP6781204B2 (ja)	2020-11-04
KR101806370B1 (ko)	2017-12-07
ZA201504813B (en)	2017-11-29
CN111499679B (zh)	2021-07-06
KR102084301B1 (ko)	2020-03-03
KR20180053599A (ko)	2018-05-23
BR112015016381A2 (pt)	2017-07-11
WO2014107652A2 (en)	2014-07-10
EP2941436A4 (en)	2016-07-27
CN105026413A (zh)	2015-11-04
CL2015001902A1 (es)	2016-02-12
CA3044471A1 (en)	2014-07-10
EP2941436A2 (en)	2015-11-11
CN111499679A (zh)	2020-08-07
TW201718004A (zh)	2017-06-01
JP2018141021A (ja)	2018-09-13
WO2014107652A3 (en)	2014-12-24

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