HK1208180A1 - Ticagrelor solid dispersion and preparation method thereof - Google Patents
Ticagrelor solid dispersion and preparation method thereofInfo
- Publication number
- HK1208180A1 HK1208180A1 HK15108906.9A HK15108906A HK1208180A1 HK 1208180 A1 HK1208180 A1 HK 1208180A1 HK 15108906 A HK15108906 A HK 15108906A HK 1208180 A1 HK1208180 A1 HK 1208180A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- preparation
- solid dispersion
- ticagrelor solid
- ticagrelor
- dispersion
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title 1
- 239000007962 solid dispersion Substances 0.000 title 1
- OEKWJQXRCDYSHL-FNOIDJSQSA-N ticagrelor Chemical compound C1([C@@H]2C[C@H]2NC=2N=C(N=C3N([C@H]4[C@@H]([C@H](O)[C@@H](OCCO)C4)O)N=NC3=2)SCCC)=CC=C(F)C(F)=C1 OEKWJQXRCDYSHL-FNOIDJSQSA-N 0.000 title 1
- 229960002528 ticagrelor Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Inorganic Chemistry (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201310432438.2A CN104434805B (en) | 2013-09-22 | 2013-09-22 | A kind of ticagrelor solid dispersions and preparation method thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1208180A1 true HK1208180A1 (en) | 2016-02-26 |
Family
ID=52688196
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK15108906.9A HK1208180A1 (en) | 2013-09-22 | 2015-09-11 | Ticagrelor solid dispersion and preparation method thereof |
Country Status (4)
Country | Link |
---|---|
CN (1) | CN104434805B (en) |
HK (1) | HK1208180A1 (en) |
TW (1) | TWI660746B (en) |
WO (1) | WO2015039513A1 (en) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111588702B (en) * | 2015-04-29 | 2023-01-20 | 江苏恒瑞医药股份有限公司 | Ticagrelor preparation of pharmaceutically acceptable salt thereof |
CN107865826B (en) * | 2016-09-27 | 2020-06-30 | 深圳微芯生物科技股份有限公司 | Solid dispersion of E-configuration benzamide compound |
WO2018229785A1 (en) * | 2017-06-15 | 2018-12-20 | Natco Pharma Limited | Pharmaceutical compositions of ticagrelor |
CN109276543B (en) * | 2017-07-19 | 2021-01-08 | 深圳微芯生物科技股份有限公司 | Sitaglipta solid dispersion and preparation method and application thereof |
CN109589312A (en) * | 2017-10-01 | 2019-04-09 | 万全万特制药(厦门)有限公司 | A kind of Aripiprazole solid dispersions and preparation method thereof |
CN110507624A (en) * | 2018-05-22 | 2019-11-29 | 江苏恒瑞医药股份有限公司 | A kind of controlled release composition of ticagrelor or its salt |
EA202190328A1 (en) | 2018-07-27 | 2021-07-01 | КРКА, д.д., НОВО МЕСТО | PHARMACEUTICAL COMPOSITION CONTAINING TICAGRELOR |
CA3119401A1 (en) * | 2018-11-16 | 2020-05-22 | Jiangsu Hengrui Medicine Co., Ltd. | Pharmaceutical composition comprising parp inhibitors |
CN113181140A (en) * | 2021-05-07 | 2021-07-30 | 苏州康恒研新药物技术有限公司 | Ticagrelor skeleton sustained-release pellet and preparation method thereof |
WO2024021802A1 (en) * | 2022-07-27 | 2024-02-01 | 江苏慧聚药业股份有限公司 | Solid ticagrelor dispersion, method for preparing same, and use thereof |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100822133B1 (en) * | 2006-11-06 | 2008-04-15 | 한미약품 주식회사 | Complex for preventing or treating osteoporosis, comprising solid dispersion of vitamin D or derivatives thereof and bisphosphonates |
ES2548845T3 (en) * | 2009-12-23 | 2015-10-21 | Ratiopharm Gmbh | Solid pharmaceutical dosage form of ticagrelor and acetylsalicylic acid |
CN102232949A (en) * | 2010-04-27 | 2011-11-09 | 孙远 | Drug dissolution increasing composition and preparation method thereof |
WO2014118808A2 (en) * | 2013-02-04 | 2014-08-07 | Hetero Research Foundation | Ticagrelor solid dispersion |
-
2013
- 2013-09-22 CN CN201310432438.2A patent/CN104434805B/en active Active
-
2014
- 2014-08-15 WO PCT/CN2014/084546 patent/WO2015039513A1/en active Application Filing
- 2014-08-22 TW TW103128925A patent/TWI660746B/en not_active IP Right Cessation
-
2015
- 2015-09-11 HK HK15108906.9A patent/HK1208180A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
WO2015039513A1 (en) | 2015-03-26 |
TWI660746B (en) | 2019-06-01 |
TW201526921A (en) | 2015-07-16 |
CN104434805B (en) | 2017-09-29 |
CN104434805A (en) | 2015-03-25 |
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