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HK1208180A1 - Ticagrelor solid dispersion and preparation method thereof - Google Patents

Ticagrelor solid dispersion and preparation method thereof

Info

Publication number
HK1208180A1
HK1208180A1 HK15108906.9A HK15108906A HK1208180A1 HK 1208180 A1 HK1208180 A1 HK 1208180A1 HK 15108906 A HK15108906 A HK 15108906A HK 1208180 A1 HK1208180 A1 HK 1208180A1
Authority
HK
Hong Kong
Prior art keywords
preparation
solid dispersion
ticagrelor solid
ticagrelor
dispersion
Prior art date
Application number
HK15108906.9A
Other languages
Chinese (zh)
Inventor
黄金昆梁力左佼
Original Assignee
Suncadia Pharmaceuticals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suncadia Pharmaceuticals Co Ltd filed Critical Suncadia Pharmaceuticals Co Ltd
Publication of HK1208180A1 publication Critical patent/HK1208180A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK15108906.9A 2013-09-22 2015-09-11 Ticagrelor solid dispersion and preparation method thereof HK1208180A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201310432438.2A CN104434805B (en) 2013-09-22 2013-09-22 A kind of ticagrelor solid dispersions and preparation method thereof

Publications (1)

Publication Number Publication Date
HK1208180A1 true HK1208180A1 (en) 2016-02-26

Family

ID=52688196

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15108906.9A HK1208180A1 (en) 2013-09-22 2015-09-11 Ticagrelor solid dispersion and preparation method thereof

Country Status (4)

Country Link
CN (1) CN104434805B (en)
HK (1) HK1208180A1 (en)
TW (1) TWI660746B (en)
WO (1) WO2015039513A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111588702B (en) * 2015-04-29 2023-01-20 江苏恒瑞医药股份有限公司 Ticagrelor preparation of pharmaceutically acceptable salt thereof
CN107865826B (en) * 2016-09-27 2020-06-30 深圳微芯生物科技股份有限公司 Solid dispersion of E-configuration benzamide compound
WO2018229785A1 (en) * 2017-06-15 2018-12-20 Natco Pharma Limited Pharmaceutical compositions of ticagrelor
CN109276543B (en) * 2017-07-19 2021-01-08 深圳微芯生物科技股份有限公司 Sitaglipta solid dispersion and preparation method and application thereof
CN109589312A (en) * 2017-10-01 2019-04-09 万全万特制药(厦门)有限公司 A kind of Aripiprazole solid dispersions and preparation method thereof
CN110507624A (en) * 2018-05-22 2019-11-29 江苏恒瑞医药股份有限公司 A kind of controlled release composition of ticagrelor or its salt
EA202190328A1 (en) 2018-07-27 2021-07-01 КРКА, д.д., НОВО МЕСТО PHARMACEUTICAL COMPOSITION CONTAINING TICAGRELOR
CA3119401A1 (en) * 2018-11-16 2020-05-22 Jiangsu Hengrui Medicine Co., Ltd. Pharmaceutical composition comprising parp inhibitors
CN113181140A (en) * 2021-05-07 2021-07-30 苏州康恒研新药物技术有限公司 Ticagrelor skeleton sustained-release pellet and preparation method thereof
WO2024021802A1 (en) * 2022-07-27 2024-02-01 江苏慧聚药业股份有限公司 Solid ticagrelor dispersion, method for preparing same, and use thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100822133B1 (en) * 2006-11-06 2008-04-15 한미약품 주식회사 Complex for preventing or treating osteoporosis, comprising solid dispersion of vitamin D or derivatives thereof and bisphosphonates
ES2548845T3 (en) * 2009-12-23 2015-10-21 Ratiopharm Gmbh Solid pharmaceutical dosage form of ticagrelor and acetylsalicylic acid
CN102232949A (en) * 2010-04-27 2011-11-09 孙远 Drug dissolution increasing composition and preparation method thereof
WO2014118808A2 (en) * 2013-02-04 2014-08-07 Hetero Research Foundation Ticagrelor solid dispersion

Also Published As

Publication number Publication date
WO2015039513A1 (en) 2015-03-26
TWI660746B (en) 2019-06-01
TW201526921A (en) 2015-07-16
CN104434805B (en) 2017-09-29
CN104434805A (en) 2015-03-25

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