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HK1207065A1 - 氮雜環衍生物及其在藥物中的應用 - Google Patents

氮雜環衍生物及其在藥物中的應用

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Publication number
HK1207065A1
HK1207065A1 HK15107599.3A HK15107599A HK1207065A1 HK 1207065 A1 HK1207065 A1 HK 1207065A1 HK 15107599 A HK15107599 A HK 15107599A HK 1207065 A1 HK1207065 A1 HK 1207065A1
Authority
HK
Hong Kong
Prior art keywords
drugs
application
heterocyclic derivatives
nitrogenous heterocyclic
nitrogenous
Prior art date
Application number
HK15107599.3A
Other languages
English (en)
Inventor
Yingjun Zhang
Jiancun Zhang
Xiaojun Wang
Runfeng Lin
Shengtian Cao
Zhaohe Wang
Jing Li
Original Assignee
Sunshine Lake Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sunshine Lake Pharma Co Ltd filed Critical Sunshine Lake Pharma Co Ltd
Publication of HK1207065A1 publication Critical patent/HK1207065A1/zh

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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
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    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
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    • C07F9/6584—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms having one phosphorus atom as ring hetero atom
    • C07F9/65842—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring
    • C07F9/65846—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring the phosphorus atom being part of a six-membered ring which may be condensed with another ring system

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CN103570630B (zh) 2016-04-20
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CA2872110C (en) 2019-08-06
AU2013292950B2 (en) 2015-09-10
ES2716008T3 (es) 2019-06-07
RU2015105262A (ru) 2016-09-10
CN103570630A (zh) 2014-02-12
EP2875001A4 (en) 2016-06-01
JP2015526411A (ja) 2015-09-10
JP6186434B2 (ja) 2017-08-23
MX2015000830A (es) 2015-10-26
EP2875001A1 (en) 2015-05-27
AU2013292950C1 (en) 2016-01-21
US20150087639A1 (en) 2015-03-26
EP2875001B1 (en) 2019-01-09
AU2013292950A1 (en) 2014-11-13
CA2872110A1 (en) 2014-01-23
KR20150036223A (ko) 2015-04-07
BR112014030284A2 (pt) 2017-06-27
BR112014030284B1 (pt) 2021-11-30
RU2701156C9 (ru) 2019-12-18
RU2701156C2 (ru) 2019-09-25
KR102057877B1 (ko) 2019-12-20

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