HK1191645A1 - -甲氧基-吡啶- -基衍生物 - Google Patents
-甲氧基-吡啶- -基衍生物Info
- Publication number
- HK1191645A1 HK1191645A1 HK14104850.5A HK14104850A HK1191645A1 HK 1191645 A1 HK1191645 A1 HK 1191645A1 HK 14104850 A HK14104850 A HK 14104850A HK 1191645 A1 HK1191645 A1 HK 1191645A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- pyridine
- methoxy
- based derivatives
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Ophthalmology & Optometry (AREA)
- Biomedical Technology (AREA)
- Oncology (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Physical Education & Sports Medicine (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Transplantation (AREA)
- Otolaryngology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IB2011050241 | 2011-01-19 | ||
PCT/IB2012/050241 WO2012098505A1 (en) | 2011-01-19 | 2012-01-18 | 2-methoxy-pyridin-4-yl derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1191645A1 true HK1191645A1 (zh) | 2014-08-01 |
Family
ID=45607310
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK14104850.5A HK1191645A1 (zh) | 2011-01-19 | 2014-05-23 | -甲氧基-吡啶- -基衍生物 |
Country Status (29)
Country | Link |
---|---|
US (1) | US9133179B2 (zh) |
EP (1) | EP2665720B1 (zh) |
JP (1) | JP5859570B2 (zh) |
KR (1) | KR101869120B1 (zh) |
CN (1) | CN103313981B (zh) |
AR (1) | AR084883A1 (zh) |
AU (1) | AU2012208325B2 (zh) |
BR (1) | BR112013017923B1 (zh) |
CA (1) | CA2818470C (zh) |
CL (1) | CL2013002056A1 (zh) |
CY (1) | CY1116657T1 (zh) |
DK (1) | DK2665720T3 (zh) |
ES (1) | ES2544086T3 (zh) |
HK (1) | HK1191645A1 (zh) |
HR (1) | HRP20150919T1 (zh) |
HU (1) | HUE026012T2 (zh) |
IL (1) | IL227509A0 (zh) |
MA (1) | MA34910B1 (zh) |
MX (1) | MX350009B (zh) |
MY (1) | MY163185A (zh) |
PH (1) | PH12013501487A1 (zh) |
PL (1) | PL2665720T3 (zh) |
PT (1) | PT2665720E (zh) |
SG (1) | SG191742A1 (zh) |
SI (1) | SI2665720T1 (zh) |
TW (1) | TWI546300B (zh) |
UA (1) | UA109804C2 (zh) |
WO (1) | WO2012098505A1 (zh) |
ZA (1) | ZA201306193B (zh) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2014229217B2 (en) | 2013-03-15 | 2017-12-14 | Idorsia Pharmaceuticals Ltd | Pyridin-4-yl derivatives |
US9629834B2 (en) | 2013-04-26 | 2017-04-25 | Kyoto University | Medicinal composition for inhibiting formation and/or enlargement of cerebral aneurysm or shrinking same |
CN105760707B (zh) * | 2014-12-18 | 2018-07-31 | 中国科学院大连化学物理研究所 | 细胞基因翻译过程建模方法 |
KR102220848B1 (ko) * | 2015-05-20 | 2021-02-26 | 이도르시아 파마슈티컬스 리미티드 | 화합물 (s)-3-{4-[5-(2-시클로펜틸-6-메톡시-피리딘-4-일)-[1,2,4]옥사디아졸-3-일]-2-에틸-6-메틸-페녹시}-프로판-1,2-디올의 결정형 |
CN107382965A (zh) * | 2017-08-14 | 2017-11-24 | 河南科技大学第附属医院 | 具有抗肿瘤活性的新型s1p‑1受体激动剂药物分子的合成方法 |
Family Cites Families (62)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3647809A (en) | 1968-04-26 | 1972-03-07 | Chinoin Gyogyszer Es Vegyeszet | Certain pyridyl-1 2 4-oxadiazole derivatives |
AU7686891A (en) | 1990-04-05 | 1991-10-30 | American National Red Cross, The | A protein family related to immediate-early protein expressed by human endothelial cells during differentiation |
CA2051494C (en) | 1990-09-20 | 2006-03-14 | Robert J. Dinerstein | 1-aryl-3-pyridinyl-2-propene-1-ones as calcium uptake inhibitors |
DE4429465A1 (de) | 1994-08-19 | 1996-02-22 | Bayer Ag | Verfahren zur Herstellung von 2-Halogenpyridinaldehyden und neue 2-Halogenpyridinaldehyde |
US6423508B1 (en) | 1998-03-09 | 2002-07-23 | Smithkline Beecham Corporation | Polynucleotide sequences of human EDG-1c |
DE19904389A1 (de) | 1999-02-04 | 2000-08-10 | Bayer Ag | Verwendung von substituierten Isoxazolcarbonsäuren und Derivate und neue Stoffe |
BR0013427A (pt) | 1999-08-19 | 2002-07-30 | Nps Pharma Inc | Compostos heteropolicìclicos e seus usos como antagonistas no receptor de glutamato metabotrópico |
KR100838447B1 (ko) | 2001-02-21 | 2008-06-16 | 아스트라제네카 아베 | 헤테로폴리시클릭 화합물 및 대사향성 글루타메이트수용체 길항제로서의 그의 용도 |
WO2003062252A1 (en) | 2002-01-18 | 2003-07-31 | Merck & Co., Inc. | Edg receptor agonists |
JP4709488B2 (ja) | 2002-01-18 | 2011-06-22 | メルク・シャープ・エンド・ドーム・コーポレイション | Edg受容体作動薬としてのN−(ベンジル)アミノアルキルカルボン酸化合物、ホスフィン酸化合物、ホスホン酸化合物およびテトラゾール類 |
AU2003276043A1 (en) | 2002-06-17 | 2003-12-31 | Merck & Co., Inc. | 1-((5-aryl-1,2,4-oxadiazol-3-yl)benzyl)azetidine-3-carboxylates and 1-((5-aryl-1,2,4-oxadiazol-3-yl)benzyl)pyrrolidine-3-carboxylates as edg receptor agonists |
DE10237883A1 (de) | 2002-08-19 | 2004-03-04 | Merckle Gmbh Chem.-Pharm. Fabrik | Substituierte Isoxazolderivate und ihre Verwendung in der Pharmazie |
WO2004035538A1 (en) | 2002-10-15 | 2004-04-29 | Merck & Co., Inc. | Process for making azetidine-3-carboxylic acid |
US20050004186A1 (en) | 2002-12-20 | 2005-01-06 | Pfizer Inc | MEK inhibiting compounds |
EP1625123A4 (en) | 2003-05-15 | 2007-08-29 | Merck & Co Inc | 3- (2-AMINO-1-AZACYCLYL) -5-ARYL-1,2,4-OXADIAZOLE AS S1P RECEPTOR AGONISTS |
TW200505416A (en) | 2003-08-12 | 2005-02-16 | Mitsubishi Pharma Corp | Bi-aryl compound having immunosuppressive activity |
EP1670463A2 (en) | 2003-10-01 | 2006-06-21 | Merck & Co., Inc. | 3,5-aryl, heteroaryl or cycloalkyl substituted-1,2,4-oxadiazoles as s1p receptor agonists |
CA2547198A1 (en) | 2003-12-17 | 2005-06-30 | Merck & Co., Inc. | (3,4-disubstituted)propanoic carboxylates as s1p (edg) receptor agonists |
EA014729B1 (ru) | 2004-05-29 | 2011-02-28 | 7ТиЭм ФАРМА А/С | Лиганды crth2 рецептора и их применение |
WO2006010379A1 (en) | 2004-07-29 | 2006-02-02 | Actelion Pharmaceuticals Ltd. | Novel thiophene derivatives as immunosuppressive agents |
AU2005299851B2 (en) | 2004-10-22 | 2011-03-17 | Merck Sharp & Dohme Corp. | 2-(aryl)azacyclylmethyl carboxylates, sulfonates, phosphonates, phosphinates and heterocycles as S1P receptor agonists |
PT1826197E (pt) | 2004-12-13 | 2012-03-06 | Ono Pharmaceutical Co | Derivado de ácido aminocarboxílico e sua utilização medicinal |
CN101180050B (zh) | 2005-03-23 | 2011-07-27 | 埃科特莱茵药品有限公司 | 作为鞘氨醇-1-磷酸盐-1受体激动剂的新颖噻吩衍生物 |
ES2365747T3 (es) | 2005-03-23 | 2011-10-10 | Actelion Pharmaceuticals Ltd. | Derivados de benzo[c]tiofeno hidrogenados como inmunomoduladores. |
PL1863474T3 (pl) | 2005-03-23 | 2009-04-30 | Actelion Pharmaceuticals Ltd | Nowe pochodne tiofenu jako agoniści receptora 1 1-fosforanu sfingozyny |
AU2006232105A1 (en) | 2005-04-05 | 2006-10-12 | Pharmacopeia, Inc. | Purine and imidazopyridine derivatives for immunosuppression |
JPWO2006115188A1 (ja) | 2005-04-22 | 2008-12-18 | 第一三共株式会社 | ヘテロ環化合物 |
ATE477253T1 (de) | 2005-04-26 | 2010-08-15 | Neurosearch As | Neuartige oxadiazol-derivate und deren medizinische verwendung |
AU2006256968A1 (en) | 2005-06-08 | 2006-12-14 | Novartis Ag | Polycyclic oxadiazoles or I soxazoles and their use as SIP receptor ligands |
US20070043104A1 (en) | 2005-06-10 | 2007-02-22 | Luthman Ingrid K | UII-modulating compounds and their use |
RU2008101805A (ru) | 2005-06-24 | 2009-07-27 | Актелион Фармасьютиклз Лтд (Ch) | Новые производные тиофена |
JP2008546836A (ja) | 2005-06-28 | 2008-12-25 | アストラゼネカ アクチボラグ | 新規な用途 |
AR057894A1 (es) | 2005-11-23 | 2007-12-26 | Actelion Pharmaceuticals Ltd | Derivados de tiofeno |
TWI404706B (zh) * | 2006-01-11 | 2013-08-11 | Actelion Pharmaceuticals Ltd | 新穎噻吩衍生物 |
PL1979345T3 (pl) | 2006-01-24 | 2010-04-30 | Actelion Pharmaceuticals Ltd | Nowe pochodne pirydyny |
GB0601744D0 (en) | 2006-01-27 | 2006-03-08 | Novartis Ag | Organic compounds |
WO2007098474A1 (en) | 2006-02-21 | 2007-08-30 | University Of Virginia Patent Foundation | Phenyl-cycloalkyl and phenyl-heterocyclic derivatives as s1p receptor agonists |
JP4383525B2 (ja) | 2006-05-09 | 2009-12-16 | ファイザー・プロダクツ・インク | シクロアルキルアミノ酸誘導体およびその医薬組成物 |
TWI408139B (zh) | 2006-09-07 | 2013-09-11 | Actelion Pharmaceuticals Ltd | 新穎噻吩衍生物 |
PL2069336T3 (pl) * | 2006-09-07 | 2013-05-31 | Idorsia Pharmaceuticals Ltd | Pochodne pirydyn-4-ylu jako środki immunomodulujące |
EP2069335B1 (en) | 2006-09-08 | 2012-12-26 | Actelion Pharmaceuticals Ltd. | Pyridin-3-yl derivatives as immunomodulating agents |
WO2008035239A1 (en) | 2006-09-21 | 2008-03-27 | Actelion Pharmaceuticals Ltd | Phenyl derivatives and their use as immunomodulators |
KR20090057070A (ko) | 2006-09-29 | 2009-06-03 | 노파르티스 아게 | 소염성 및 면역억제성을 갖는 옥사디아졸 유도체 |
JP2008120794A (ja) | 2006-10-16 | 2008-05-29 | Daiichi Sankyo Co Ltd | ヘテロ環化合物を含有する医薬組成物 |
BRPI0720043A2 (pt) | 2006-12-15 | 2014-01-07 | Abbott Lab | Composto oxadiazol |
US20110207704A1 (en) | 2006-12-15 | 2011-08-25 | Abbott Laboratories | Novel Oxadiazole Compounds |
WO2008091967A1 (en) | 2007-01-26 | 2008-07-31 | Smithkline Beecham Corporation | Chemical compounds |
ES2450750T3 (es) * | 2007-03-16 | 2014-03-25 | Actelion Pharmaceuticals Ltd. | Derivados de amino-piridina como agonistas del receptor S1P1/EDG1 |
JP5451614B2 (ja) | 2007-08-17 | 2014-03-26 | アクテリオン ファーマシューティカルズ リミテッド | S1p1/edg1受容体調節剤としてのピリジン誘導体 |
EP2193125B1 (en) | 2007-10-04 | 2017-01-11 | Merck Serono S.A. | Oxadiazole derivatives |
CA2696829C (en) | 2007-10-04 | 2017-07-04 | Merck Serono S.A. | Oxadiazole diaryl compounds |
CN101970430B (zh) | 2007-11-01 | 2013-05-08 | 埃科特莱茵药品有限公司 | 嘧啶衍生物 |
JP2011503046A (ja) | 2007-11-08 | 2011-01-27 | ファイザー・インク | シクロブチルカルボン酸誘導体 |
US8148410B2 (en) | 2007-12-10 | 2012-04-03 | Actelion Pharmaceuticals Ltd. | Thiophene derivatives as agonists of S1P1/EDG1 |
WO2009078983A1 (en) * | 2007-12-18 | 2009-06-25 | Arena Pharmaceuticals, Inc. | Tetrahydrocyclopenta[b]indol-3-yl carboxylic acid derivatives useful in the treatment of autoimmune and inflammatory disorders |
JP2011513385A (ja) | 2008-03-06 | 2011-04-28 | アクテリオン ファーマシューティカルズ リミテッド | 新規なピリミジン−ピリジン誘導体 |
ES2389042T3 (es) | 2008-03-06 | 2012-10-22 | Actelion Pharmaceuticals Ltd. | Compuestos de piridina |
MY183039A (en) | 2008-03-07 | 2021-02-08 | Idorsia Pharmaceuticals Ltd | Pyridin-2-yl derivatives as immunomodulating agents |
WO2009109904A1 (en) | 2008-03-07 | 2009-09-11 | Actelion Pharmaceuticals Ltd | Novel aminomethyl benzene derivatives |
ES2813368T3 (es) | 2008-05-14 | 2021-03-23 | Scripps Research Inst | Nuevos moduladores de receptores de fosfato de esfingosina |
TW201107302A (en) | 2009-06-26 | 2011-03-01 | Glaxo Group Ltd | Compounds |
WO2011007324A1 (en) * | 2009-07-16 | 2011-01-20 | Actelion Pharmaceuticals Ltd | Pyridin-4-yl derivatives |
-
2012
- 2012-01-18 PH PH1/2013/501487A patent/PH12013501487A1/en unknown
- 2012-01-18 MX MX2013007726A patent/MX350009B/es active IP Right Grant
- 2012-01-18 TW TW101101997A patent/TWI546300B/zh active
- 2012-01-18 HU HUE12704125A patent/HUE026012T2/en unknown
- 2012-01-18 UA UAA201309611A patent/UA109804C2/ru unknown
- 2012-01-18 BR BR112013017923-6A patent/BR112013017923B1/pt not_active IP Right Cessation
- 2012-01-18 ES ES12704125.9T patent/ES2544086T3/es active Active
- 2012-01-18 DK DK12704125.9T patent/DK2665720T3/en active
- 2012-01-18 SG SG2013047212A patent/SG191742A1/en unknown
- 2012-01-18 EP EP12704125.9A patent/EP2665720B1/en active Active
- 2012-01-18 MA MA36184A patent/MA34910B1/fr unknown
- 2012-01-18 CN CN201280005493.7A patent/CN103313981B/zh not_active Expired - Fee Related
- 2012-01-18 KR KR1020137020321A patent/KR101869120B1/ko not_active Expired - Fee Related
- 2012-01-18 PL PL12704125T patent/PL2665720T3/pl unknown
- 2012-01-18 AR ARP120100163A patent/AR084883A1/es unknown
- 2012-01-18 AU AU2012208325A patent/AU2012208325B2/en not_active Ceased
- 2012-01-18 MY MYPI2013701260A patent/MY163185A/en unknown
- 2012-01-18 CA CA2818470A patent/CA2818470C/en active Active
- 2012-01-18 JP JP2013549917A patent/JP5859570B2/ja not_active Expired - Fee Related
- 2012-01-18 WO PCT/IB2012/050241 patent/WO2012098505A1/en active Application Filing
- 2012-01-18 SI SI201230254T patent/SI2665720T1/sl unknown
- 2012-01-18 PT PT127041259T patent/PT2665720E/pt unknown
- 2012-01-18 US US13/980,764 patent/US9133179B2/en active Active
-
2013
- 2013-07-17 IL IL227509A patent/IL227509A0/en active IP Right Grant
- 2013-07-17 CL CL2013002056A patent/CL2013002056A1/es unknown
- 2013-08-16 ZA ZA2013/06193A patent/ZA201306193B/en unknown
-
2014
- 2014-05-23 HK HK14104850.5A patent/HK1191645A1/zh not_active IP Right Cessation
-
2015
- 2015-08-28 CY CY20151100762T patent/CY1116657T1/el unknown
- 2015-09-02 HR HRP20150919TT patent/HRP20150919T1/hr unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CO6890099A2 (es) | Nuevos derivados dihidroquinolina-2-ona | |
DK2744810T4 (da) | Tenofovir-alafenamid-hemifumarat | |
EP2780065A4 (en) | NASAL MASK SYSTEM | |
EP2768410A4 (en) | EXTENSION COLLAR SYSTEM | |
EP2664141A4 (en) | UNBLOCKING FILTERING | |
DK2769050T3 (da) | Propsensor | |
EP2748335A4 (en) | BIOLOGICAL MARKERS OF URINE | |
BR112014000879A2 (pt) | deflegmador | |
DE102011100082A8 (de) | Traygreifvorrichtung | |
DK3272861T3 (da) | Alpha-galactosidase-sammensætninger | |
EP2795884A4 (en) | Audio conferencing | |
CO6960543A2 (es) | 2-tiopirimidinonas | |
EP2786752A4 (en) | Ropinirole-containing adhesive patch | |
EP2768739A4 (en) | EYEWASH FLUID CONTAINER | |
DK3141251T3 (da) | Koloskopi - forberedelse | |
CO6960557A2 (es) | Derivados de 2-yodo-imidazol | |
EP2738148A4 (en) | RECIPROCAL LOCKING BLOCK | |
DE112011104936A5 (de) | Stanzstauchniet | |
PL2762466T3 (pl) | Pochodna fenylu | |
EP2760803A4 (en) | Geopolymer product | |
HK1191645A1 (zh) | -甲氧基-吡啶- -基衍生物 | |
EP2788163A4 (en) | POST-MOLDING SYSTEM | |
EP2729467A4 (en) | CRYPTATE COMPOUNDS | |
EP2698098A4 (en) | campimeter | |
DE112012000958A5 (de) | Handsäge |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20200121 |