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HK1182143A1 - 空間編碼的生物測定法 - Google Patents

空間編碼的生物測定法 Download PDF

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Publication number
HK1182143A1
HK1182143A1 HK13109501.8A HK13109501A HK1182143A1 HK 1182143 A1 HK1182143 A1 HK 1182143A1 HK 13109501 A HK13109501 A HK 13109501A HK 1182143 A1 HK1182143 A1 HK 1182143A1
Authority
HK
Hong Kong
Prior art keywords
oligonucleotide
tissue sample
biological assays
spatially encoded
target protein
Prior art date
Application number
HK13109501.8A
Other languages
English (en)
Other versions
HK1182143B (zh
Inventor
Mark S. Chee
Original Assignee
Prognosys Biosciences, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44710331&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1182143(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Prognosys Biosciences, Inc. filed Critical Prognosys Biosciences, Inc.
Publication of HK1182143A1 publication Critical patent/HK1182143A1/zh
Publication of HK1182143B publication Critical patent/HK1182143B/zh

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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809Methods for determination or identification of nucleic acids involving differential detection
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6804Nucleic acid analysis using immunogens
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6834Enzymatic or biochemical coupling of nucleic acids to a solid phase
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6834Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6841In situ hybridisation
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
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    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00Methods of screening libraries
    • C40B30/04Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
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    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B60/00Apparatus specially adapted for use in combinatorial chemistry or with libraries
    • C40B60/04Integrated apparatus specially adapted for both screening libraries and identifying library members
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6845Methods of identifying protein-protein interactions in protein mixtures
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00Labels used in chemical analysis of biological material
    • G01N2458/10Oligonucleotides as tagging agents for labelling antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Clinical Laboratory Science (AREA)
  • Dispersion Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
HK13109501.8A 2010-04-05 2011-04-05 空間編碼的生物測定法 HK1182143B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US32112410P 2010-04-05 2010-04-05
US61/321,124 2010-04-05
US13/080,616 US9371598B2 (en) 2010-04-05 2011-04-05 Spatially encoded biological assays
PCT/US2011/031308 WO2011127099A1 (en) 2010-04-05 2011-04-05 Spatially encoded biological assays
US13/080,616 2011-04-05

Publications (2)

Publication Number Publication Date
HK1182143A1 true HK1182143A1 (zh) 2013-11-22
HK1182143B HK1182143B (zh) 2016-08-26

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Also Published As

Publication number Publication date
DK2556171T3 (en) 2015-12-14
US10612079B2 (en) 2020-04-07
US20200208205A1 (en) 2020-07-02
US20200048690A1 (en) 2020-02-13
HK1222210A1 (zh) 2017-06-23
KR20130100051A (ko) 2013-09-09
EP2556171B1 (en) 2015-09-02
CA2794522C (en) 2019-11-26
ES2555106T3 (es) 2015-12-29
US10472669B2 (en) 2019-11-12
AU2011237729A1 (en) 2012-10-25
US20200208206A1 (en) 2020-07-02
PT2556171E (pt) 2015-12-21
US20110245111A1 (en) 2011-10-06
US10662467B2 (en) 2020-05-26
US20200140935A1 (en) 2020-05-07
WO2011127099A1 (en) 2011-10-13
US20200063196A1 (en) 2020-02-27
US20210270822A1 (en) 2021-09-02
CN105385756B (zh) 2020-12-25
RS54482B1 (en) 2016-06-30
PL2556171T3 (pl) 2016-04-29
US20190309354A1 (en) 2019-10-10
SI2556171T1 (sl) 2016-03-31
US10982268B2 (en) 2021-04-20
US10308982B2 (en) 2019-06-04
US20190271030A1 (en) 2019-09-05
US10619196B1 (en) 2020-04-14
CN102834526A (zh) 2012-12-19
US20190300944A1 (en) 2019-10-03
US10962532B2 (en) 2021-03-30
CA2794522A1 (en) 2011-10-13
US9371598B2 (en) 2016-06-21
US11067567B2 (en) 2021-07-20
US20200224256A1 (en) 2020-07-16
CN105385756A (zh) 2016-03-09
US10996219B2 (en) 2021-05-04
EP2556171A1 (en) 2013-02-13
KR101866401B1 (ko) 2018-06-11
US20190300943A1 (en) 2019-10-03
AU2011237729B2 (en) 2014-04-03
US20190323071A1 (en) 2019-10-24
JP2013523151A (ja) 2013-06-17
US10983113B2 (en) 2021-04-20
US20190177778A1 (en) 2019-06-13
US10662468B2 (en) 2020-05-26
US20190309353A1 (en) 2019-10-10
US20190309355A1 (en) 2019-10-10
US20200140934A1 (en) 2020-05-07
US10494667B2 (en) 2019-12-03
US11156603B2 (en) 2021-10-26
JP5893607B2 (ja) 2016-03-23
CN102834526B (zh) 2015-12-02
SMT201500301B (it) 2016-02-25
US10914730B2 (en) 2021-02-09
US20160298180A1 (en) 2016-10-13
US10480022B2 (en) 2019-11-19
HRP20151294T1 (hr) 2016-03-11
US20200063195A1 (en) 2020-02-27
US20210130884A1 (en) 2021-05-06
US20190177777A1 (en) 2019-06-13
EP2556171A4 (en) 2014-02-12
HUE026666T2 (en) 2016-07-28

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