HK1127609A1 - Phenyl-pyrazole derivatives as non-steroidal glucocoricoid receptor ligands - Google Patents

Phenyl-pyrazole derivatives as non-steroidal glucocoricoid receptor ligands

Info

Publication number: HK1127609A1
Authority: HK; Hong Kong
Prior art keywords: phenyl; receptor ligands; pyrazole derivatives; steroidal glucocoricoid; glucocoricoid receptor
Prior art date: 2006-06-12

Application number

HK09106729.6A

Other languages

English (en)

Inventor

Heather Anne Barnett

Ian Baxter Campbell

Diane Mary Coe

Anthony William James Cooper

Graham George Adam Inglis

Haydn Terence Jones

Steven Philip Keeling

Simon John Fawcett Macdonald

Iain Mcfarlane Mclay

Philip Alan Skone

Gordon Gad Weingarten

James Michael Woolven

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-06-12

Filing date

2009-07-22

Publication date

2009-10-02

2006-12-20 Priority claimed from GB0625457A external-priority patent/GB0625457D0/en

2007-05-29 Priority claimed from GB0710217A external-priority patent/GB0710217D0/en

2009-07-22 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

2009-10-02 Publication of HK1127609A1 publication Critical patent/HK1127609A1/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/10—Expectorants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pulmonology (AREA)
Immunology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Dermatology (AREA)
Neurosurgery (AREA)
Physical Education & Sports Medicine (AREA)
Rheumatology (AREA)
Communicable Diseases (AREA)
Pain & Pain Management (AREA)
Ophthalmology & Optometry (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Oncology (AREA)
Transplantation (AREA)
Orthopedic Medicine & Surgery (AREA)
Otolaryngology (AREA)
Anesthesiology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Epoxy Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

HK09106729.6A 2006-06-12 2009-07-22 Phenyl-pyrazole derivatives as non-steroidal glucocoricoid receptor ligands HK1127609A1 (en)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
GBGB0611587.7A GB0611587D0 (en)	2006-06-12	2006-06-12	Novel compounds
GB0625457A GB0625457D0 (en)	2006-12-20	2006-12-20	Novel compounds
GB0710217A GB0710217D0 (en)	2007-05-29	2007-05-29	Novel compounds
PCT/EP2007/055724 WO2007144327A2 (en)	2006-06-12	2007-06-11	Phenyl-pyrazole derivatives as non-steroidal glucocoricoid receptor ligands

Publications (1)

Publication Number	Publication Date
HK1127609A1 true HK1127609A1 (en)	2009-10-02

Family

ID=38659745

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HK09106729.6A HK1127609A1 (en)	2006-06-12	2009-07-22	Phenyl-pyrazole derivatives as non-steroidal glucocoricoid receptor ligands

Country Status (29)

Country	Link
US (2)	US8247377B2 (xx)
EP (1)	EP2029549B1 (xx)
JP (1)	JP5497433B2 (xx)
KR (1)	KR101411276B1 (xx)
CN (1)	CN101501003B (xx)
AR (1)	AR061341A1 (xx)
AT (1)	ATE487703T1 (xx)
AU (1)	AU2007260067B2 (xx)
BR (1)	BRPI0713755A8 (xx)
CA (1)	CA2659564C (xx)
CR (1)	CR10489A (xx)
CY (1)	CY1111454T1 (xx)
DE (1)	DE602007010456D1 (xx)
DK (1)	DK2029549T3 (xx)
EA (1)	EA015540B1 (xx)
ES (1)	ES2355165T3 (xx)
GB (1)	GB0611587D0 (xx)
HK (1)	HK1127609A1 (xx)
HR (1)	HRP20110097T1 (xx)
IL (1)	IL195492A0 (xx)
MA (1)	MA30514B1 (xx)
MX (1)	MX2008015977A (xx)
NO (1)	NO20085100L (xx)
PL (1)	PL2029549T3 (xx)
PT (1)	PT2029549E (xx)
SI (1)	SI2029549T1 (xx)
TW (1)	TW200815360A (xx)
WO (1)	WO2007144327A2 (xx)
ZA (1)	ZA200810161B (xx)

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2006
- 2006-06-12 GB GBGB0611587.7A patent/GB0611587D0/en not_active Ceased
2007
- 2007-06-11 EP EP07765362A patent/EP2029549B1/en active Active
- 2007-06-11 DK DK07765362.4T patent/DK2029549T3/da active
- 2007-06-11 CN CN2007800295932A patent/CN101501003B/zh active Active
- 2007-06-11 MX MX2008015977A patent/MX2008015977A/es active IP Right Grant
- 2007-06-11 AU AU2007260067A patent/AU2007260067B2/en active Active
- 2007-06-11 JP JP2009514772A patent/JP5497433B2/ja active Active
- 2007-06-11 EA EA200802322A patent/EA015540B1/ru not_active IP Right Cessation
- 2007-06-11 AT AT07765362T patent/ATE487703T1/de active
- 2007-06-11 US US12/303,791 patent/US8247377B2/en active Active
- 2007-06-11 SI SI200730484T patent/SI2029549T1/sl unknown
- 2007-06-11 TW TW096121030A patent/TW200815360A/zh unknown
- 2007-06-11 PL PL07765362T patent/PL2029549T3/pl unknown
- 2007-06-11 AR ARP070102547A patent/AR061341A1/es unknown
- 2007-06-11 CA CA2659564A patent/CA2659564C/en active Active
- 2007-06-11 KR KR1020097000591A patent/KR101411276B1/ko active IP Right Grant
- 2007-06-11 BR BRPI0713755A patent/BRPI0713755A8/pt not_active Application Discontinuation
- 2007-06-11 DE DE602007010456T patent/DE602007010456D1/de active Active
- 2007-06-11 WO PCT/EP2007/055724 patent/WO2007144327A2/en active Application Filing
- 2007-06-11 ES ES07765362T patent/ES2355165T3/es active Active
- 2007-06-11 PT PT07765362T patent/PT2029549E/pt unknown
2008
- 2008-11-25 IL IL195492A patent/IL195492A0/en unknown
- 2008-11-28 ZA ZA200810161A patent/ZA200810161B/xx unknown
- 2008-12-08 NO NO20085100A patent/NO20085100L/no not_active Application Discontinuation
- 2008-12-10 CR CR10489A patent/CR10489A/es not_active Application Discontinuation
- 2008-12-12 MA MA31473A patent/MA30514B1/fr unknown
2009
- 2009-07-22 HK HK09106729.6A patent/HK1127609A1/xx unknown
2011
- 2011-02-02 CY CY20111100112T patent/CY1111454T1/el unknown
- 2011-02-08 HR HR20110097T patent/HRP20110097T1/hr unknown
2012
- 2012-07-13 US US13/548,573 patent/US20120277279A1/en not_active Abandoned

Also Published As

Publication number	Publication date
EA015540B1 (ru)	2011-08-30
AU2007260067B2 (en)	2012-10-04
CA2659564A1 (en)	2007-12-21
TW200815360A (en)	2008-04-01
US8247377B2 (en)	2012-08-21
CA2659564C (en)	2013-12-10
AU2007260067A1 (en)	2007-12-21
SI2029549T1 (sl)	2011-03-31
PL2029549T3 (pl)	2011-04-29
GB0611587D0 (en)	2006-07-19
DK2029549T3 (da)	2011-02-21
PT2029549E (pt)	2011-02-02
HRP20110097T1 (hr)	2011-03-31
NO20085100L (no)	2009-01-07
WO2007144327A3 (en)	2008-04-10
US20100234441A1 (en)	2010-09-16
EP2029549B1 (en)	2010-11-10
JP2009539926A (ja)	2009-11-19
US20120277279A1 (en)	2012-11-01
ES2355165T3 (es)	2011-03-23
KR20090018726A (ko)	2009-02-20
WO2007144327A2 (en)	2007-12-21
BRPI0713755A8 (pt)	2018-01-09
ATE487703T1 (de)	2010-11-15
MA30514B1 (fr)	2009-06-01
CR10489A (es)	2009-03-20
CN101501003B (zh)	2013-05-08
EP2029549A2 (en)	2009-03-04
EA200802322A1 (ru)	2009-06-30
JP5497433B2 (ja)	2014-05-21
AR061341A1 (es)	2008-08-20
CN101501003A (zh)	2009-08-05
IL195492A0 (en)	2009-09-22
CY1111454T1 (el)	2015-08-05
ZA200810161B (en)	2010-05-26
BRPI0713755A2 (pt)	2012-11-06
MX2008015977A (es)	2009-03-30
KR101411276B1 (ko)	2014-06-24
DE602007010456D1 (de)	2010-12-23

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