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HK1124640A1 - Sequencing and genotyping using reversibly 2'-modified nucleotides - Google Patents

Sequencing and genotyping using reversibly 2'-modified nucleotides

Info

Publication number
HK1124640A1
HK1124640A1 HK09102530.4A HK09102530A HK1124640A1 HK 1124640 A1 HK1124640 A1 HK 1124640A1 HK 09102530 A HK09102530 A HK 09102530A HK 1124640 A1 HK1124640 A1 HK 1124640A1
Authority
HK
Hong Kong
Prior art keywords
genotyping
reversibly
sequencing
modified nucleotides
nucleotides
Prior art date
Application number
HK09102530.4A
Other languages
English (en)
Inventor
David H Gelfand
Amar P Gupta
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of HK1124640A1 publication Critical patent/HK1124640A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
HK09102530.4A 2005-12-21 2009-03-17 Sequencing and genotyping using reversibly 2'-modified nucleotides HK1124640A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US75282705P 2005-12-21 2005-12-21
US84404106P 2006-09-11 2006-09-11
PCT/US2006/048933 WO2007075967A2 (en) 2005-12-21 2006-12-20 Sequencing and genotyping using reversibly 2'-modified nucleotides

Publications (1)

Publication Number Publication Date
HK1124640A1 true HK1124640A1 (en) 2009-07-17

Family

ID=38218645

Family Applications (1)

Application Number Title Priority Date Filing Date
HK09102530.4A HK1124640A1 (en) 2005-12-21 2009-03-17 Sequencing and genotyping using reversibly 2'-modified nucleotides

Country Status (8)

Country Link
US (1) US9206476B2 (ja)
EP (1) EP1974057B1 (ja)
JP (1) JP5368108B2 (ja)
CN (1) CN101346472B (ja)
CA (1) CA2631316C (ja)
ES (1) ES2388722T3 (ja)
HK (1) HK1124640A1 (ja)
WO (1) WO2007075967A2 (ja)

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US7947817B2 (en) 2003-06-30 2011-05-24 Roche Molecular Systems, Inc. Synthesis and compositions of 2'-terminator nucleotides
US7572581B2 (en) 2003-06-30 2009-08-11 Roche Molecular Systems, Inc. 2′-terminator nucleotide-related methods and systems
US7928207B2 (en) 2004-06-28 2011-04-19 Roche Molecular Systems, Inc Synthesis and compositions of nucleic acids comprising 2′-terminator nucleotides
US7745125B2 (en) 2004-06-28 2010-06-29 Roche Molecular Systems, Inc. 2′-terminator related pyrophosphorolysis activated polymerization
US8212020B2 (en) * 2005-03-11 2012-07-03 Steven Albert Benner Reagents for reversibly terminating primer extension
CA2631316C (en) 2005-12-21 2012-12-04 F. Hoffmann-La Roche Ag Sequencing and genotyping using reversibly 2'-modified nucleotides
WO2008042067A2 (en) * 2006-09-28 2008-04-10 Illumina, Inc. Compositions and methods for nucleotide sequencing
EP2155855B1 (en) * 2007-06-06 2016-10-12 Pacific Biosciences of California, Inc. Methods and processes for calling bases in sequence by incorporation methods
US8703422B2 (en) * 2007-06-06 2014-04-22 Pacific Biosciences Of California, Inc. Methods and processes for calling bases in sequence by incorporation methods
WO2013154750A1 (en) 2012-04-10 2013-10-17 The Trustees Of Columbia Unversity In The City Of New York Systems and methods for biological ion channel interfaces
WO2010111690A2 (en) * 2009-03-27 2010-09-30 Life Technologies Corporation Polymerase compositions and methods
US20100279882A1 (en) * 2009-05-01 2010-11-04 Mostafa Ronaghi Sequencing methods
WO2010141390A2 (en) 2009-06-05 2010-12-09 Life Technologies Corporation Nucleotide transient binding for sequencing methods
US20100330556A1 (en) * 2009-06-30 2010-12-30 Brian Jon Peter Genome analysis using a nicking endonuclease
DK2456892T3 (en) 2009-07-24 2014-12-08 Illumina Inc Procedure for sequencing of a polynukleotidskabelon
EP2663862A4 (en) 2011-01-11 2015-01-21 Univ Columbia SYSTEMS AND METHOD FOR SINGLE-MOLECULAR DETECTION USING NANOTUBES
WO2012116161A1 (en) 2011-02-23 2012-08-30 The Trustees Of Columbia University In The City Of New York Systems and methods for single-molecule detection using nanopores
US10378051B2 (en) * 2011-09-29 2019-08-13 Illumina Cambridge Limited Continuous extension and deblocking in reactions for nucleic acids synthesis and sequencing
CN107082792A (zh) * 2012-04-09 2017-08-22 纽约哥伦比亚大学理事会 纳米孔的制备方法和其用途
WO2013158280A1 (en) 2012-04-20 2013-10-24 The Trustees Of Columbia University In The City Of New York Systems and methods for single-molecule nucleic-acid assay platforms
US9770713B2 (en) * 2012-08-30 2017-09-26 Hitachi High-Technologies Corporation Nucleic acid analysis device
US9650406B2 (en) 2013-02-28 2017-05-16 Centrillion Technology Holdings Corporation Reversible terminator molecules and methods of their use
US9146248B2 (en) 2013-03-14 2015-09-29 Intelligent Bio-Systems, Inc. Apparatus and methods for purging flow cells in nucleic acid sequencing instruments
US9591268B2 (en) 2013-03-15 2017-03-07 Qiagen Waltham, Inc. Flow cell alignment methods and systems
EP2970366B1 (en) 2013-03-15 2019-01-16 Ibis Biosciences, Inc. Nucleotide analogs for sequencing
EP3091026B1 (en) 2015-05-08 2019-02-20 Centrillion Technology Holdings Corporation Disulfide-linked reversible terminators
CN109072297B (zh) 2016-04-22 2022-09-13 加利福尼亚太平洋生物科学股份有限公司 使用增强的核苷酸特异性三元复合物形成检测的核酸测序方法和系统
JP7133473B2 (ja) * 2016-05-20 2022-09-08 クアンタム－エスアイ インコーポレイテッド 標識ヌクレオチド組成物および核酸の配列を決定するための方法
JP7058228B2 (ja) * 2016-06-24 2022-04-21 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 繋ぎ止められたヌクレオシド三リン酸を用いた核酸合成および配列決定
CN108239669B (zh) * 2016-12-23 2021-03-16 深圳华大智造科技股份有限公司 检测可逆性阻断dNTP中非阻断杂质含量的方法和试剂盒
EP3571319A1 (en) 2017-01-20 2019-11-27 Omniome, Inc. Process for cognate nucleotide detection in a nucleic acid sequencing workflow
EP3625240A4 (en) 2017-05-18 2021-01-27 Ultima Genomics, Inc. SEQUENCING USING NON-NATURAL NUCLEOTIDES
US11655504B2 (en) 2017-07-24 2023-05-23 Quantum-Si Incorporated High intensity labeled reactant compositions and methods for sequencing
WO2019099420A1 (en) * 2017-11-15 2019-05-23 Yan Wang A method for detecting multiple dna mutations and copy number variations
US20190241945A1 (en) * 2018-02-06 2019-08-08 Omniome, Inc. Compositions and techniques for nucleic acid primer extension
WO2020069424A1 (en) 2018-09-28 2020-04-02 Centrillion Technologies, Inc. Disulfide-linked reversible terminators
KR20210118862A (ko) 2019-01-23 2021-10-01 퀀텀-에스아이 인코포레이티드 고강도 표지된 반응물 조성물 및 서열분석 방법
JP2023518105A (ja) * 2019-12-30 2023-04-27 源點生物科技股▲フン▼有限公司 酵素を使用して核酸配列を調製するための方法
EP4084899A4 (en) * 2019-12-30 2023-09-27 Yuandian Biolabs Co., Ltd. APPARATUS AND METHOD FOR PREPARING NUCLEIC ACID SEQUENCES USING ENZYMES
WO2021185320A1 (en) * 2020-03-18 2021-09-23 Mgi Tech Co., Ltd. Restoring phase in massively parallel sequencing

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5302509A (en) * 1989-08-14 1994-04-12 Beckman Instruments, Inc. Method for sequencing polynucleotides
US5436143A (en) * 1992-12-23 1995-07-25 Hyman; Edward D. Method for enzymatic synthesis of oligonucleotides
US5532130A (en) 1993-07-20 1996-07-02 Dyad Pharmaceutical Corporation Methods and compositions for sequence-specific hybridization of RNA by 2'-5' oligonucleotides
US7270951B1 (en) * 1999-03-10 2007-09-18 Asm Scientific, Inc. Method for direct nucleic acid sequencing
US7572581B2 (en) * 2003-06-30 2009-08-11 Roche Molecular Systems, Inc. 2′-terminator nucleotide-related methods and systems
US7947817B2 (en) * 2003-06-30 2011-05-24 Roche Molecular Systems, Inc. Synthesis and compositions of 2'-terminator nucleotides
ATE407939T1 (de) 2004-06-02 2008-09-15 Asm Scient Inc 2ß-NITROBENZYL-MODIFIZIERTE RIBONUKLEOTIDE
US7745125B2 (en) 2004-06-28 2010-06-29 Roche Molecular Systems, Inc. 2′-terminator related pyrophosphorolysis activated polymerization
CA2631316C (en) 2005-12-21 2012-12-04 F. Hoffmann-La Roche Ag Sequencing and genotyping using reversibly 2'-modified nucleotides
EP1987944B1 (de) 2007-05-04 2012-07-25 Leister Technologies AG Laserdurchstrahlschweissvorrichtung und Verfahren zum Verbinden von Kunststoffwerkstücken

Also Published As

Publication number Publication date
ES2388722T3 (es) 2012-10-18
WO2007075967B1 (en) 2008-02-21
EP1974057A2 (en) 2008-10-01
CA2631316A1 (en) 2007-07-05
CN101346472B (zh) 2013-04-24
WO2007075967A3 (en) 2008-01-03
CN101346472A (zh) 2009-01-14
US20080293071A1 (en) 2008-11-27
EP1974057B1 (en) 2012-06-13
US9206476B2 (en) 2015-12-08
CA2631316C (en) 2012-12-04
JP5368108B2 (ja) 2013-12-18
JP2009521223A (ja) 2009-06-04
WO2007075967A2 (en) 2007-07-05

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