HK1054391A1 - 毒蕈碱拮抗劑 - Google Patents
毒蕈碱拮抗劑Info
- Publication number
- HK1054391A1 HK1054391A1 HK03106691.6A HK03106691A HK1054391A1 HK 1054391 A1 HK1054391 A1 HK 1054391A1 HK 03106691 A HK03106691 A HK 03106691A HK 1054391 A1 HK1054391 A1 HK 1054391A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- muscarinic antagonists
- muscarinic
- antagonists
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US25785300P | 2000-12-22 | 2000-12-22 | |
PCT/US2001/049063 WO2002051808A2 (en) | 2000-12-22 | 2001-12-17 | Muscarinic antagonists |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1054391A1 true HK1054391A1 (zh) | 2003-11-28 |
Family
ID=22978046
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK03106691.6A HK1054391A1 (zh) | 2000-12-22 | 2003-09-18 | 毒蕈碱拮抗劑 |
Country Status (15)
Country | Link |
---|---|
US (1) | US6458812B1 (zh) |
EP (1) | EP1343760B1 (zh) |
JP (2) | JP4012068B2 (zh) |
CN (1) | CN1481360A (zh) |
AR (1) | AR035612A1 (zh) |
AT (1) | ATE439344T1 (zh) |
AU (1) | AU2002235224A1 (zh) |
CA (1) | CA2431952C (zh) |
DE (1) | DE60139571D1 (zh) |
ES (1) | ES2329975T3 (zh) |
HK (1) | HK1054391A1 (zh) |
MX (1) | MXPA03005743A (zh) |
MY (1) | MY133992A (zh) |
PE (1) | PE20020657A1 (zh) |
WO (1) | WO2002051808A2 (zh) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7592348B2 (en) | 2003-12-15 | 2009-09-22 | Schering Corporation | Heterocyclic aspartyl protease inhibitors |
US7763609B2 (en) | 2003-12-15 | 2010-07-27 | Schering Corporation | Heterocyclic aspartyl protease inhibitors |
US7700603B2 (en) * | 2003-12-15 | 2010-04-20 | Schering Corporation | Heterocyclic aspartyl protease inhibitors |
US9132135B2 (en) * | 2004-09-24 | 2015-09-15 | University Of Maryland, Baltimore | Method of treating organophosphorous poisoning |
US7888346B2 (en) * | 2004-09-24 | 2011-02-15 | Universtiy of Maryland, Baltimore | Method of treating organophosphorous poisoning |
US7559932B2 (en) * | 2004-12-06 | 2009-07-14 | Dfine, Inc. | Bone treatment systems and methods |
US7678116B2 (en) | 2004-12-06 | 2010-03-16 | Dfine, Inc. | Bone treatment systems and methods |
US7722620B2 (en) | 2004-12-06 | 2010-05-25 | Dfine, Inc. | Bone treatment systems and methods |
TW201004961A (en) | 2005-06-14 | 2010-02-01 | Schering Corp | Aspartyl protease inhibitors |
MX2007016182A (es) * | 2005-06-14 | 2008-03-07 | Schering Corp | Inhibidores de aspartil proteasas. |
US7812013B2 (en) * | 2005-06-14 | 2010-10-12 | Schering Corporation | Macrocyclic heterocyclic aspartyl protease inhibitors |
ES2436795T3 (es) | 2005-06-14 | 2014-01-07 | Merck Sharp & Dohme Corp. | Inhibidores heterocíclicos de aspartil proteasa, preparación y uso de los mismos |
MX2007016177A (es) | 2005-06-14 | 2008-03-07 | Schering Corp | La preparacion y uso de compuestos como inhibidores de aspartil proteasas. |
US20080027456A1 (en) * | 2006-07-19 | 2008-01-31 | Csaba Truckai | Bone treatment systems and methods |
US8696679B2 (en) | 2006-12-08 | 2014-04-15 | Dfine, Inc. | Bone treatment systems and methods |
MX2009006228A (es) | 2006-12-12 | 2009-06-22 | Schering Corp | Inhibidores de aspartil proteasa. |
CA2672295A1 (en) * | 2006-12-12 | 2008-06-19 | Schering Corporation | Aspartyl protease inhibitors containing a tricyclic ring system |
WO2008137428A2 (en) | 2007-04-30 | 2008-11-13 | Dfine, Inc. | Bone treatment systems and methods |
JP2010538068A (ja) | 2007-09-06 | 2010-12-09 | シェーリング コーポレイション | ガンマセクレターゼモジュレーター |
CA2704698A1 (en) | 2007-11-05 | 2009-05-14 | Schering Corporation | Gamma secretase modulators |
EP2227471A1 (en) * | 2007-12-11 | 2010-09-15 | Schering Corporation | Gamma secretase modulators |
WO2010056849A1 (en) | 2008-11-13 | 2010-05-20 | Schering Corporation | Gamma secretase modulators |
CA2747744A1 (en) | 2008-12-22 | 2010-07-01 | Theodros Asberom | Gamma secretase modulators |
WO2010075204A2 (en) | 2008-12-22 | 2010-07-01 | Schering Corporation | Gamma secretase modulators |
US20120010264A1 (en) * | 2009-03-26 | 2012-01-12 | Dainippon Sumitomo Pharma Co., Ltd. | Novel medicament for treating cognitive impairment |
US20120245158A1 (en) | 2009-06-16 | 2012-09-27 | Xianhai Huang | Gamma secretase modulators |
US20120238546A1 (en) | 2009-06-16 | 2012-09-20 | Zhaoning Zhu | Gamma secretase modulators |
EP2443118A1 (en) | 2009-06-16 | 2012-04-25 | Schering Corporation | Gamma secretase modulators |
US20110281853A1 (en) | 2010-05-12 | 2011-11-17 | Rishi Arora | Compositions and methods for treating or preventing atrial fibrillation |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH04312572A (ja) * | 1991-04-12 | 1992-11-04 | Takeda Chem Ind Ltd | 環状アミン化合物 |
IL117149A0 (en) | 1995-02-23 | 1996-06-18 | Schering Corp | Muscarinic antagonists |
TW542822B (en) * | 1997-01-17 | 2003-07-21 | Ajinomoto Kk | Benzamidine derivatives |
US6066636A (en) | 1998-06-30 | 2000-05-23 | Schering Corporation | Muscarinic antagonists |
-
2001
- 2001-12-17 CA CA002431952A patent/CA2431952C/en not_active Expired - Fee Related
- 2001-12-17 AT AT01985584T patent/ATE439344T1/de not_active IP Right Cessation
- 2001-12-17 EP EP01985584A patent/EP1343760B1/en not_active Expired - Lifetime
- 2001-12-17 DE DE60139571T patent/DE60139571D1/de not_active Expired - Lifetime
- 2001-12-17 US US10/023,277 patent/US6458812B1/en not_active Expired - Fee Related
- 2001-12-17 AR ARP010105838A patent/AR035612A1/es unknown
- 2001-12-17 MX MXPA03005743A patent/MXPA03005743A/es active IP Right Grant
- 2001-12-17 CN CNA018209718A patent/CN1481360A/zh active Pending
- 2001-12-17 ES ES01985584T patent/ES2329975T3/es not_active Expired - Lifetime
- 2001-12-17 AU AU2002235224A patent/AU2002235224A1/en not_active Abandoned
- 2001-12-17 WO PCT/US2001/049063 patent/WO2002051808A2/en active Application Filing
- 2001-12-17 JP JP2002552905A patent/JP4012068B2/ja not_active Expired - Fee Related
- 2001-12-18 PE PE2001001266A patent/PE20020657A1/es not_active Application Discontinuation
- 2001-12-19 MY MYPI20015743A patent/MY133992A/en unknown
-
2003
- 2003-09-18 HK HK03106691.6A patent/HK1054391A1/zh unknown
-
2007
- 2007-08-03 JP JP2007203608A patent/JP2007297410A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
MY133992A (en) | 2007-11-30 |
AR035612A1 (es) | 2004-06-16 |
AU2002235224A1 (en) | 2002-07-08 |
DE60139571D1 (de) | 2009-09-24 |
WO2002051808A3 (en) | 2003-01-23 |
CA2431952A1 (en) | 2002-07-04 |
JP2007297410A (ja) | 2007-11-15 |
CA2431952C (en) | 2010-03-09 |
PE20020657A1 (es) | 2002-07-23 |
CN1481360A (zh) | 2004-03-10 |
US6458812B1 (en) | 2002-10-01 |
EP1343760B1 (en) | 2009-08-12 |
ATE439344T1 (de) | 2009-08-15 |
ES2329975T3 (es) | 2009-12-03 |
JP4012068B2 (ja) | 2007-11-21 |
WO2002051808A2 (en) | 2002-07-04 |
EP1343760A2 (en) | 2003-09-17 |
MXPA03005743A (es) | 2003-09-05 |
JP2004516313A (ja) | 2004-06-03 |
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