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HK1046133A1 - Pharmaceutical compounds. - Google Patents

Pharmaceutical compounds.

Info

Publication number
HK1046133A1
HK1046133A1 HK02107392A HK02107392A HK1046133A1 HK 1046133 A1 HK1046133 A1 HK 1046133A1 HK 02107392 A HK02107392 A HK 02107392A HK 02107392 A HK02107392 A HK 02107392A HK 1046133 A1 HK1046133 A1 HK 1046133A1
Authority
HK
Hong Kong
Prior art keywords
pharmaceutical compounds
pharmaceutical
compounds
Prior art date
Application number
HK02107392A
Other versions
HK1046133B (en
Inventor
John Milton
Nigel Vicker
Adrian John Folkes
Shouming Wang
William Alexander Denny
Original Assignee
Xenova Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xenova Ltd filed Critical Xenova Ltd
Publication of HK1046133A1 publication Critical patent/HK1046133A1/en
Publication of HK1046133B publication Critical patent/HK1046133B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/46Phenazines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK02107392.7A 1999-12-02 2002-10-10 Pharmaceutical compounds HK1046133B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9928542.1A GB9928542D0 (en) 1999-12-02 1999-12-02 Pharmaceutical compounds
PCT/GB2000/004609 WO2001046157A1 (en) 1999-12-02 2000-12-01 Benzo[a]phenazin-11-carboxamide derivatives and their use as joint inhibitors of topomerase i and ii

Publications (2)

Publication Number Publication Date
HK1046133A1 true HK1046133A1 (en) 2002-12-27
HK1046133B HK1046133B (en) 2005-04-15

Family

ID=10865607

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02107392.7A HK1046133B (en) 1999-12-02 2002-10-10 Pharmaceutical compounds

Country Status (16)

Country Link
EP (1) EP1240148A1 (en)
JP (1) JP2003518103A (en)
KR (1) KR100767613B1 (en)
CN (1) CN1304380C (en)
AU (1) AU784397B2 (en)
BR (1) BR0016093A (en)
CA (1) CA2392873A1 (en)
GB (2) GB9928542D0 (en)
HK (1) HK1046133B (en)
HU (1) HUP0300392A3 (en)
MX (1) MXPA02005476A (en)
MY (1) MY136029A (en)
PL (1) PL356482A1 (en)
TW (1) TWI280242B (en)
WO (1) WO2001046157A1 (en)
ZA (1) ZA200204296B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2433071A (en) * 2005-12-05 2007-06-13 Kontrakt Technology Ltd Organic acids comprising planar conjugated heterocyclic molecular system, & photoelectric layer thereof with rodlike supramolecules for use in solar cell
CN102898388B (en) * 2012-09-26 2014-12-03 浙江工业大学 Method for synthesizing substituted benzo[alpha]phenazine compound
CN103360329B (en) * 2013-07-18 2015-11-18 中国科学院南海海洋研究所 One class compound phenazine and preparing the application in antitumor drug
CN106554321B (en) * 2015-09-25 2019-05-28 陆源 A kind of azophenlyene substance, preparation method and its application
CN113461623A (en) * 2021-07-14 2021-10-01 长江大学 Antiviral compound and preparation method and application thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69329336D1 (en) * 1992-05-28 2000-10-05 Xenova Ltd ACRIDIN CARBOXAMIDE FOR TREATING CANCER
US5696131A (en) * 1993-01-22 1997-12-09 Xenova Limited Treatment of cancers
KR20000048537A (en) * 1996-09-23 2000-07-25 루트거스, 더 스테이트 유니버시티 오브 뉴 저지 Substituted heterocycles as anti-tumor agents
WO1998045272A1 (en) * 1997-04-07 1998-10-15 Latrobe University Topoisomerase inhibitors

Also Published As

Publication number Publication date
AU784397B2 (en) 2006-03-23
GB9928542D0 (en) 2000-02-02
CN1433406A (en) 2003-07-30
EP1240148A1 (en) 2002-09-18
HK1046133B (en) 2005-04-15
MXPA02005476A (en) 2003-09-22
TWI280242B (en) 2007-05-01
ZA200204296B (en) 2003-05-29
PL356482A1 (en) 2004-06-28
CN1304380C (en) 2007-03-14
KR100767613B1 (en) 2007-10-19
AU1718401A (en) 2001-07-03
GB2373499A (en) 2002-09-25
WO2001046157A1 (en) 2001-06-28
JP2003518103A (en) 2003-06-03
GB0215275D0 (en) 2002-08-14
BR0016093A (en) 2002-08-20
KR20020070305A (en) 2002-09-05
HUP0300392A2 (en) 2003-07-28
GB2373499B (en) 2004-11-17
HUP0300392A3 (en) 2003-09-29
CA2392873A1 (en) 2001-06-28
MY136029A (en) 2008-07-31

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20081201