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HK1024001A1 - Diphenyl alkyl-tetrahydropyridines, process for their preparation, and pharmaceutical compositions containing them - Google Patents

Diphenyl alkyl-tetrahydropyridines, process for their preparation, and pharmaceutical compositions containing them Download PDF

Info

Publication number
HK1024001A1
HK1024001A1 HK00103246A HK00103246A HK1024001A1 HK 1024001 A1 HK1024001 A1 HK 1024001A1 HK 00103246 A HK00103246 A HK 00103246A HK 00103246 A HK00103246 A HK 00103246A HK 1024001 A1 HK1024001 A1 HK 1024001A1
Authority
HK
Hong Kong
Prior art keywords
tetrahydropyridine
formula
trifluoromethylphenyl
compound
ethyl
Prior art date
Application number
HK00103246A
Other languages
English (en)
Chinese (zh)
Other versions
HK1024001B (en
Inventor
M‧巴罗尼
R‧卡达蒙尼
J‧福尼尔
U‧古奇
Original Assignee
赛诺菲 - 安万特公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 赛诺菲 - 安万特公司 filed Critical 赛诺菲 - 安万特公司
Publication of HK1024001A1 publication Critical patent/HK1024001A1/xx
Publication of HK1024001B publication Critical patent/HK1024001B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK00103246.6A 1996-12-13 1997-12-12 Diphenyl alkyl-tetrahydropyridines, process for their preparation, and pharmaceutical compositions containing them HK1024001B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR96/15336 1996-12-13
FR9615336A FR2757161B1 (fr) 1996-12-13 1996-12-13 Diphenylalkyl-tetrahydropyridines
PCT/FR1997/002289 WO1998025904A1 (fr) 1996-12-13 1997-12-12 Diphenylalkyl-tetrahydropyridines, procede pour leur preparation et composition pharmaceutique les contenant

Publications (2)

Publication Number Publication Date
HK1024001A1 true HK1024001A1 (en) 2000-09-29
HK1024001B HK1024001B (en) 2004-12-31

Family

ID=

Also Published As

Publication number Publication date
HUP0001437A3 (en) 2001-12-28
DK0950049T3 (da) 2002-01-28
AU730142B2 (en) 2001-03-01
NZ336032A (en) 2000-12-22
PT950049E (pt) 2002-03-28
CN1144784C (zh) 2004-04-07
BR9713926A (pt) 2000-03-21
IS2001B (is) 2005-04-15
DE69707504T2 (de) 2002-06-27
CZ211099A3 (cs) 1999-09-15
IS5074A (is) 1999-06-10
SI0950049T1 (en) 2002-10-31
NO992870L (no) 1999-08-11
YU26399A (sh) 2000-03-21
SK78799A3 (en) 1999-12-10
ES2167805T3 (es) 2002-05-16
NO313282B1 (no) 2002-09-09
PL192926B1 (pl) 2006-12-29
ATE207056T1 (de) 2001-11-15
CY2282B1 (en) 2003-07-04
CN1240428A (zh) 2000-01-05
EP0950049B1 (fr) 2001-10-17
EE03764B1 (et) 2002-06-17
NO992870D0 (no) 1999-06-11
CA2274946A1 (en) 1998-06-18
EE9900238A (et) 1999-12-15
IL130001A0 (en) 2000-02-29
JP2001505903A (ja) 2001-05-08
CA2274946C (en) 2005-09-20
AU5489598A (en) 1998-07-03
CZ290242B6 (cs) 2002-06-12
KR20000069421A (ko) 2000-11-25
SK283332B6 (sk) 2003-06-03
RU2198874C2 (ru) 2003-02-20
PL334073A1 (en) 2000-01-31
EP0950049A1 (fr) 1999-10-20
HUP0001437A2 (hu) 2000-09-28
UA52708C2 (uk) 2003-01-15
IL130001A (en) 2006-04-10
KR100549656B1 (ko) 2006-02-08
FR2757161A1 (fr) 1998-06-19
DE69707504D1 (de) 2001-11-22
WO1998025904A1 (fr) 1998-06-18
TR199901290T2 (xx) 1999-08-23
FR2757161B1 (fr) 1999-03-12
RS49672B (sr) 2007-11-15
US6124318A (en) 2000-09-26

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Legal Events

Date Code Title Description
CHRG Changes in the register
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20081212