GT200500215A - Amidas sustituidas de àcido tienopirrolcarboxìlico, amidas del àcido pirrolotiazolcarboxìlico y anàlogos relacionados como inhibidores de la epsilon caseìna quinasa i - Google Patents
Amidas sustituidas de àcido tienopirrolcarboxìlico, amidas del àcido pirrolotiazolcarboxìlico y anàlogos relacionados como inhibidores de la epsilon caseìna quinasa iInfo
- Publication number
- GT200500215A GT200500215A GT200500215A GT200500215A GT200500215A GT 200500215 A GT200500215 A GT 200500215A GT 200500215 A GT200500215 A GT 200500215A GT 200500215 A GT200500215 A GT 200500215A GT 200500215 A GT200500215 A GT 200500215A
- Authority
- GT
- Guatemala
- Prior art keywords
- acid
- quinasa
- inhibitors
- tienopirrolcarboxylic
- pirrolotiazolcarboxylic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Anesthesiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Peptides Or Proteins (AREA)
Abstract
LA PRESENTE INVENCIÒN SE REFIERE A COMPUESTOS DE LAS FÒRMULAS GENERALES I Y II EN LAS QUE M,L,X,R1,R2,R3,R4, SON GRUPOS FUNCIONALES DESCRITOS EN EL EXPEDIENTE. ESTOS COMPUESTOS SON INHIBIDORES DE LA FOSFORILACIÒN DE LA CASEÌNA QUINASA POR LO QUE SON DE UTILIDAD EN EL TRATAMIENTO Y/O LA PREVENCIÒN DE ENFERMEDADES Y TRASTORNOS ASOCIADOS CON EL SISTEMA NERVIOSO CENTRAL.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US60334704P | 2004-08-19 | 2004-08-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GT200500215A true GT200500215A (es) | 2006-03-27 |
Family
ID=35695546
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GT200500215A GT200500215A (es) | 2004-08-19 | 2005-08-09 | Amidas sustituidas de àcido tienopirrolcarboxìlico, amidas del àcido pirrolotiazolcarboxìlico y anàlogos relacionados como inhibidores de la epsilon caseìna quinasa i |
Country Status (31)
| Country | Link |
|---|---|
| US (2) | US7393867B2 (es) |
| EP (1) | EP1784409B1 (es) |
| JP (1) | JP4869232B2 (es) |
| KR (1) | KR20070045263A (es) |
| CN (1) | CN100562521C (es) |
| AR (1) | AR051008A1 (es) |
| AT (1) | ATE471326T1 (es) |
| AU (1) | AU2005272584B2 (es) |
| BR (1) | BRPI0514419A (es) |
| CA (1) | CA2577879C (es) |
| CY (1) | CY1110775T1 (es) |
| DE (1) | DE602005021889D1 (es) |
| DK (1) | DK1784409T3 (es) |
| ES (1) | ES2347166T3 (es) |
| GT (1) | GT200500215A (es) |
| HK (1) | HK1105198A1 (es) |
| HR (1) | HRP20100475T1 (es) |
| IL (1) | IL181158A0 (es) |
| JO (1) | JO2629B1 (es) |
| MY (1) | MY139831A (es) |
| PA (1) | PA8642801A1 (es) |
| PE (1) | PE20060630A1 (es) |
| PL (1) | PL1784409T3 (es) |
| PT (1) | PT1784409E (es) |
| RS (1) | RS51413B (es) |
| RU (1) | RU2403257C2 (es) |
| SI (1) | SI1784409T1 (es) |
| SV (1) | SV2006002190A (es) |
| TW (1) | TWI372149B (es) |
| UY (1) | UY29077A1 (es) |
| WO (1) | WO2006021000A2 (es) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005066135A2 (en) | 2003-12-29 | 2005-07-21 | Sepracor Inc. | Pyrrole and pyrazole daao inhibitors |
| NZ569630A (en) | 2006-01-06 | 2011-09-30 | Sepracor Inc | Cycloalkylamines as monoamine reuptake inhibitors |
| CN101426372A (zh) | 2006-01-06 | 2009-05-06 | 塞普拉柯公司 | 基于四氢萘酮的单胺再摄取抑制剂 |
| ES2643602T3 (es) | 2006-03-31 | 2017-11-23 | Sunovion Pharmaceuticals Inc. | Aminas y quirales |
| US7884124B2 (en) | 2006-06-30 | 2011-02-08 | Sepracor Inc. | Fluoro-substituted inhibitors of D-amino acid oxidase |
| US7902252B2 (en) | 2007-01-18 | 2011-03-08 | Sepracor, Inc. | Inhibitors of D-amino acid oxidase |
| EP1955699A1 (en) * | 2007-02-08 | 2008-08-13 | Boehringer Ingelheim Pharma GmbH & Co. KG | Use of flibanserin for the treatment of insomnia |
| JP5420534B2 (ja) | 2007-05-31 | 2014-02-19 | サノビオン ファーマシューティカルズ インク | モノアミン再取り込み阻害薬としてのフェニル置換シクロアルキルアミン |
| WO2010092660A1 (ja) * | 2009-02-12 | 2010-08-19 | 株式会社ファルマデザイン | カゼインキナーゼ１δ及びカゼインキナーゼ１ε阻害剤 |
| PL2435443T3 (pl) * | 2009-05-28 | 2014-01-31 | Vertex Pharma | Aminopirazolotriazolotiadiazolowe inhibitory kinazy białka c-Met |
| WO2011051858A1 (en) * | 2009-10-28 | 2011-05-05 | Pfizer Inc. | Imidazole derivatives as casein kinase inhibitors |
| DE102009058280A1 (de) * | 2009-12-14 | 2011-06-16 | Merck Patent Gmbh | Thiazolderivate |
| CN103097380B (zh) | 2010-08-09 | 2015-06-03 | 株式会社创药分子设计 | 酪蛋白激酶1δ及酪蛋白激酶1ε抑制剂 |
| CN109748927A (zh) * | 2017-11-03 | 2019-05-14 | 上海交通大学医学院附属瑞金医院 | 杂芳基酰胺类化合物、其制备方法、药用组合物及其应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000075669A1 (en) * | 1999-06-08 | 2000-12-14 | Aventis Pharmaceuticals Inc. | Screening methods for altering circadian rhythm proteins |
| JP4691506B2 (ja) * | 2003-12-11 | 2011-06-01 | アベンティス・ファーマスーティカルズ・インコーポレイテツド | カゼインキナーゼＩεの阻害剤としての置換１Ｈ−ピロロ［３，２−ｂ，３，２−ｃ，及び２，３−ｃ］ピリジン−２−カルボキシアミド及び関連類似物 |
-
2005
- 2005-07-18 JO JO2005104A patent/JO2629B1/en active
- 2005-08-09 GT GT200500215A patent/GT200500215A/es unknown
- 2005-08-09 SV SV2005002190A patent/SV2006002190A/es not_active Application Discontinuation
- 2005-08-16 AR ARP050103439A patent/AR051008A1/es unknown
- 2005-08-17 PE PE2005000956A patent/PE20060630A1/es not_active Application Discontinuation
- 2005-08-18 BR BRPI0514419-1A patent/BRPI0514419A/pt not_active Application Discontinuation
- 2005-08-18 JP JP2007528007A patent/JP4869232B2/ja not_active Expired - Fee Related
- 2005-08-18 EP EP05826812A patent/EP1784409B1/en active Active
- 2005-08-18 AU AU2005272584A patent/AU2005272584B2/en not_active Ceased
- 2005-08-18 SI SI200531094T patent/SI1784409T1/sl unknown
- 2005-08-18 PL PL05826812T patent/PL1784409T3/pl unknown
- 2005-08-18 DE DE602005021889T patent/DE602005021889D1/de active Active
- 2005-08-18 AT AT05826812T patent/ATE471326T1/de active
- 2005-08-18 ES ES05826812T patent/ES2347166T3/es active Active
- 2005-08-18 DK DK05826812.9T patent/DK1784409T3/da active
- 2005-08-18 CN CNB2005800269958A patent/CN100562521C/zh not_active Expired - Fee Related
- 2005-08-18 WO PCT/US2005/029383 patent/WO2006021000A2/en active Application Filing
- 2005-08-18 MY MYPI20053879A patent/MY139831A/en unknown
- 2005-08-18 RU RU2007109812/04A patent/RU2403257C2/ru not_active IP Right Cessation
- 2005-08-18 KR KR1020077003865A patent/KR20070045263A/ko not_active Abandoned
- 2005-08-18 CA CA2577879A patent/CA2577879C/en not_active Expired - Fee Related
- 2005-08-18 RS RSP-2010/0401A patent/RS51413B/en unknown
- 2005-08-18 PT PT05826812T patent/PT1784409E/pt unknown
- 2005-08-19 TW TW094128282A patent/TWI372149B/zh not_active IP Right Cessation
- 2005-08-19 UY UY29077A patent/UY29077A1/es not_active Application Discontinuation
- 2005-08-19 PA PA20058642801A patent/PA8642801A1/es unknown
-
2007
- 2007-02-04 IL IL181158A patent/IL181158A0/en unknown
- 2007-02-13 US US11/674,349 patent/US7393867B2/en active Active
- 2007-09-27 HK HK07110482.7A patent/HK1105198A1/xx not_active IP Right Cessation
-
2008
- 2008-05-22 US US12/125,450 patent/US7652046B2/en active Active
-
2010
- 2010-08-31 HR HR20100475T patent/HRP20100475T1/hr unknown
- 2010-09-09 CY CY20101100823T patent/CY1110775T1/el unknown
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