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GT200300232A - Compuestos de purina y usos de los mismos - Google Patents

Compuestos de purina y usos de los mismos

Info

Publication number
GT200300232A
GT200300232A GT200300232A GT200300232A GT200300232A GT 200300232 A GT200300232 A GT 200300232A GT 200300232 A GT200300232 A GT 200300232A GT 200300232 A GT200300232 A GT 200300232A GT 200300232 A GT200300232 A GT 200300232A
Authority
GT
Guatemala
Prior art keywords
same
purine compounds
useful
compounds
receiver
Prior art date
Application number
GT200300232A
Other languages
English (en)
Inventor
David Andrew Griffith
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GT200300232A publication Critical patent/GT200300232A/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/28—Oxygen atom
    • C07D473/30—Oxygen atom attached in position 6, e.g. hypoxanthine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/40—Heterocyclic compounds containing purine ring systems with halogen atoms or perhalogeno-alkyl radicals directly attached in position 2 or 6

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Reproductive Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychology (AREA)
  • Cardiology (AREA)
  • Oncology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Child & Adolescent Psychology (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Communicable Diseases (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE AL COMPUESTO DE FORMULA GENERAL I EN LA QUE R1,A,B,R4, SON GRUPOS FUNCIONALES DESCRITOS EN EL EXPEDIENTE. ESTOS COMPUESTOS SON UTILES COMO LIGANDOS DE RECEPTOR DE CANNABINOIDES, EN PARTICULAR COMO ANTAGONISTAS DEL RECEPTOR CB1 POR LO QUE SON DE UTILIDAD EN CUADROS DE OBESIDAD
GT200300232A 2002-10-28 2003-10-27 Compuestos de purina y usos de los mismos GT200300232A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US42187402P 2002-10-28 2002-10-28

Publications (1)

Publication Number Publication Date
GT200300232A true GT200300232A (es) 2004-06-23

Family

ID=32176739

Family Applications (1)

Application Number Title Priority Date Filing Date
GT200300232A GT200300232A (es) 2002-10-28 2003-10-27 Compuestos de purina y usos de los mismos

Country Status (45)

Country Link
US (2) US7129239B2 (es)
EP (1) EP1558615B8 (es)
JP (2) JP3954618B2 (es)
KR (1) KR100674560B1 (es)
CN (3) CN100478343C (es)
AP (1) AP1916A (es)
AR (1) AR041835A1 (es)
AT (1) ATE371658T1 (es)
AU (1) AU2003269368B2 (es)
BR (1) BR0314918A (es)
CA (1) CA2503900C (es)
CO (1) CO5560546A2 (es)
CR (1) CR7812A (es)
CU (1) CU23535A3 (es)
CY (1) CY1107505T1 (es)
DE (1) DE60316012T2 (es)
DK (1) DK1558615T3 (es)
DO (1) DOP2003000742A (es)
EA (1) EA008176B1 (es)
EC (1) ECSP055767A (es)
EG (1) EG24662A (es)
ES (1) ES2291669T3 (es)
GE (1) GEP20084325B (es)
GT (1) GT200300232A (es)
HK (2) HK1081189A1 (es)
HR (1) HRP20050378A2 (es)
IS (1) IS2602B (es)
MA (1) MA27479A1 (es)
MX (1) MXPA05003882A (es)
MY (1) MY140010A (es)
NL (1) NL1024643C2 (es)
NO (1) NO332195B1 (es)
NZ (1) NZ539589A (es)
OA (1) OA13080A (es)
PE (1) PE20040781A1 (es)
PL (1) PL376311A1 (es)
PT (1) PT1558615E (es)
RS (2) RS20050306A (es)
SG (1) SG148071A1 (es)
TN (1) TNSN05121A1 (es)
TW (1) TWI327567B (es)
UA (1) UA79507C2 (es)
UY (1) UY28044A1 (es)
WO (1) WO2004037823A1 (es)
ZA (1) ZA200503378B (es)

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