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GT200100037A - THE 5-ALQUILPIRIDO (2,3-D) PYRIMIDINS ARE INHIBITORS OF THYROSINE KINES AND DEPENDS ON THE CYCLINE. - Google Patents

THE 5-ALQUILPIRIDO (2,3-D) PYRIMIDINS ARE INHIBITORS OF THYROSINE KINES AND DEPENDS ON THE CYCLINE.

Info

Publication number
GT200100037A
GT200100037A GT200100037A GT200100037A GT200100037A GT 200100037 A GT200100037 A GT 200100037A GT 200100037 A GT200100037 A GT 200100037A GT 200100037 A GT200100037 A GT 200100037A GT 200100037 A GT200100037 A GT 200100037A
Authority
GT
Guatemala
Prior art keywords
cycline
inhibitors
depends
alquilpirido
pyrimidins
Prior art date
Application number
GT200100037A
Other languages
Spanish (es)
Inventor
Booth Richard John
Dobrusin Ellen Myra
Toogood Peter Laurence
Vaderwel Scott Norman
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GT200100037A publication Critical patent/GT200100037A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

ESTA INVENCION SE REFIERE A LA 5ALQUILPRIDOPIRIMIDINAS CON INHIBIDORES DE LAS CINASAS QUE DEPENDEN DE LA CICLINA, EN PARTICULAR DE LA CINASA 4 QUE DEPENDE DE LA CICLINA. LOS COMPUESTOS DE LA INVENCION SON UTILES PARA EL TRATAMIENTO DE LA INFLAMACION, LAS ENFERMEDADES PROLIFERATIVAS DE LAS CELULAS COMO EL CANCER Y LA RESTENOSIS, Y LAS ENFERMEDADES NEURODEGENERATIVAS, COMO LA ENFERMEDAD DE ALZHEIMER.THIS INVENTION REFERS TO THE 5ALQUILPRIDOPIRIMIDINAS WITH INHIBITORS OF THE KINASES THAT DEPEND ON THE CYCLINE, IN PARTICULAR OF THE KINASE 4 THAT DEPENDS ON THE CYCLINE. THE COMPOUNDS OF THE INVENTION ARE USEFUL FOR THE TREATMENT OF INFLAMMATION, PROLIFERATIVE DISEASES OF CELLS LIKE CANCER AND RESTENOSIS, AND NEURODEGENERATIVE DISEASES, LIKE ALZHEIMER'S DISEASE.

GT200100037A 2000-03-06 2001-03-05 THE 5-ALQUILPIRIDO (2,3-D) PYRIMIDINS ARE INHIBITORS OF THYROSINE KINES AND DEPENDS ON THE CYCLINE. GT200100037A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US18712400P 2000-03-06 2000-03-06

Publications (1)

Publication Number Publication Date
GT200100037A true GT200100037A (en) 2002-03-04

Family

ID=22687699

Family Applications (1)

Application Number Title Priority Date Filing Date
GT200100037A GT200100037A (en) 2000-03-06 2001-03-05 THE 5-ALQUILPIRIDO (2,3-D) PYRIMIDINS ARE INHIBITORS OF THYROSINE KINES AND DEPENDS ON THE CYCLINE.

Country Status (36)

Country Link
EP (1) EP1268476A1 (en)
JP (1) JP2003528101A (en)
KR (1) KR20020075805A (en)
CN (1) CN1422268A (en)
AP (1) AP2002002643A0 (en)
AR (1) AR034119A1 (en)
AU (1) AU2001233028A1 (en)
BG (1) BG107161A (en)
BR (1) BR0109056A (en)
CA (1) CA2401368A1 (en)
CO (1) CO5280200A1 (en)
CR (1) CR6736A (en)
CZ (1) CZ20022929A3 (en)
DZ (1) DZ3308A1 (en)
EA (1) EA200200802A1 (en)
EE (1) EE200200506A (en)
GT (1) GT200100037A (en)
HN (1) HN2001000040A (en)
HR (1) HRP20020798A2 (en)
HU (1) HUP0300136A2 (en)
IL (1) IL151480A0 (en)
IS (1) IS6524A (en)
MA (1) MA26881A1 (en)
MX (1) MXPA02008535A (en)
NO (1) NO20024235L (en)
NZ (1) NZ520962A (en)
OA (1) OA12227A (en)
PA (1) PA8513201A1 (en)
PE (1) PE20011177A1 (en)
PL (1) PL358271A1 (en)
SK (1) SK12472002A3 (en)
SV (1) SV2001000338A (en)
TN (1) TNSN01036A1 (en)
WO (1) WO2001070741A1 (en)
YU (1) YU66502A (en)
ZA (1) ZA200207110B (en)

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Also Published As

Publication number Publication date
JP2003528101A (en) 2003-09-24
NO20024235D0 (en) 2002-09-05
PA8513201A1 (en) 2003-06-30
EA200200802A1 (en) 2003-02-27
CO5280200A1 (en) 2003-05-30
HN2001000040A (en) 2001-09-06
HRP20020798A2 (en) 2004-02-29
DZ3308A1 (en) 2001-09-27
SV2001000338A (en) 2001-11-30
SK12472002A3 (en) 2003-04-01
PE20011177A1 (en) 2001-11-23
CN1422268A (en) 2003-06-04
KR20020075805A (en) 2002-10-05
HUP0300136A2 (en) 2003-05-28
EP1268476A1 (en) 2003-01-02
AR034119A1 (en) 2004-02-04
OA12227A (en) 2004-03-18
WO2001070741A1 (en) 2001-09-27
MXPA02008535A (en) 2002-12-13
PL358271A1 (en) 2004-08-09
NZ520962A (en) 2003-09-26
EE200200506A (en) 2004-02-16
IS6524A (en) 2002-08-23
ZA200207110B (en) 2003-12-04
CR6736A (en) 2004-03-10
YU66502A (en) 2005-09-19
MA26881A1 (en) 2004-12-20
IL151480A0 (en) 2003-04-10
BR0109056A (en) 2003-06-03
NO20024235L (en) 2002-11-05
TNSN01036A1 (en) 2005-11-10
BG107161A (en) 2003-06-30
AU2001233028A1 (en) 2001-10-03
AP2002002643A0 (en) 2002-12-31
CA2401368A1 (en) 2001-09-27
CZ20022929A3 (en) 2003-02-12

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