GT200000194A - Quimioterapia de combinacion. - Google Patents
Quimioterapia de combinacion.Info
- Publication number
- GT200000194A GT200000194A GT200000194A GT200000194A GT200000194A GT 200000194 A GT200000194 A GT 200000194A GT 200000194 A GT200000194 A GT 200000194A GT 200000194 A GT200000194 A GT 200000194A GT 200000194 A GT200000194 A GT 200000194A
- Authority
- GT
- Guatemala
- Prior art keywords
- agents
- combination
- carboplatin
- paclitaxel
- compartment
- Prior art date
Links
- 238000009096 combination chemotherapy Methods 0.000 title 1
- 190000008236 CARBOPLATIN Chemical compound 0.000 abstract 4
- 229960004562 carboplatin Drugs 0.000 abstract 4
- 229930012538 Paclitaxel Natural products 0.000 abstract 3
- 229960001592 paclitaxel Drugs 0.000 abstract 3
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 abstract 3
- 230000002195 synergetic effect Effects 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 208000037844 advanced solid tumor Diseases 0.000 abstract 1
- 230000000118 anti-neoplastic effect Effects 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
LA INVENCION SE REFIERE A UN METODO PARA TRATAR TUMORES SOLIDOS AVANZADOS UTILIZANDO COMBINACIONES DE AGENTES ONCOLITICOS CONOCIDOS. EL USO DE LOS AGENTES JUNTOS PROPORCIONA INESPERADAMENTE UN EFICACIA MAYOR QUE SI SE EMPLEAN COMO AGENTES SIMPLES SOLAMENTE. HEMOS DESCUBIERTO UNA UNICA COMBINACION DE AGENTES ONCOLITICOS CONOCIDOS QUE EXHIBE UNA IMPORTANTE EFECTO SINERGETICO. LA COMBINACION UTILIZA EL AGENTE ACETILDINALINA, JUNTO CON PACLITAXEL Y/O CARBOPLATINA, EN UNA COMBINACION BINARIA O CON LOS TRES COMPONENTES SIMULTANEAMENTE. LA INVENCION COMPRENDE ADEMAS FORMULACIONES FARMACOLOGICAMENTE EFECTIVAS, TRATAMIENTOS, ADEMAS DE LA PRESENTACION EN UN COMPARTIMIENTO DE DOSIFICACION DE ACETIDINALINA Y EN OTRO COMPARTIMIENTO UNA DOSIFICACION DE CARBOPLATINA Y/O OTRO COMPARTIMIENTO DE DOSIFICACION DE PACLITAXEL. UNA COMBINACION DE AGENTES ANTINEOPLASICOS QUE COMPRENDEN UNA CANTIDAD ANTITUMOR DE ACETIDINALINA Y UNA CANTIDAD ANTITUMOR DE PACLITAXEL Y / O CARBOPLATINA. LA ACETILDINALINA EN COMBINACION CON PACLITAXEL Y / O CARBOPLATINA ES SINERGISTICA PARA TRATAR EL CANCER.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16488999P | 1999-11-10 | 1999-11-10 | |
| US22256100P | 2000-08-03 | 2000-08-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GT200000194A true GT200000194A (es) | 2002-05-03 |
Family
ID=26860956
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GT200000194A GT200000194A (es) | 1999-11-10 | 2000-11-09 | Quimioterapia de combinacion. |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP1229916A2 (es) |
| JP (1) | JP2003513912A (es) |
| KR (1) | KR20020060226A (es) |
| CN (1) | CN1387438A (es) |
| AR (1) | AR026400A1 (es) |
| AU (1) | AU1583201A (es) |
| CA (1) | CA2386876A1 (es) |
| GT (1) | GT200000194A (es) |
| HU (1) | HUP0203153A3 (es) |
| IL (1) | IL149363A0 (es) |
| NZ (1) | NZ518668A (es) |
| PA (1) | PA8506201A1 (es) |
| PE (1) | PE20011028A1 (es) |
| PL (1) | PL355170A1 (es) |
| SV (1) | SV2001000212A (es) |
| UY (1) | UY26431A1 (es) |
| WO (1) | WO2001034131A2 (es) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ20022216A3 (cs) * | 2001-07-02 | 2003-05-14 | Warner-Lambert Company | Kombinační chemoterapie |
| PE20050206A1 (es) * | 2003-05-26 | 2005-03-26 | Schering Ag | Composicion farmaceutica que contiene un inhibidor de histona deacetilasa |
| AU2004296764B2 (en) * | 2003-12-02 | 2011-04-28 | The Ohio State University Research Foundation | Zn2+ -chelating motif-tethered short -chain fatty acids as a novel class of histone deacetylase inhibitors |
| US7951780B2 (en) | 2004-02-25 | 2011-05-31 | Astellas Pharma Inc. | Antitumor agent |
| KR20070036130A (ko) * | 2004-07-16 | 2007-04-02 | 화이자 프로덕츠 인코포레이티드 | 항-아이지에프-1알 항체를 사용하는 비-혈액학적악성종양에 대한 조합 치료 |
| PL2415382T3 (pl) | 2010-08-06 | 2013-02-28 | Electrolux Home Products Corp Nv | Zmywarka nablatowa |
| EP3461480A1 (en) | 2017-09-27 | 2019-04-03 | Onxeo | Combination of a dna damage response cell cycle checkpoint inhibitors and belinostat for treating cancer |
| EP3461488A1 (en) | 2017-09-27 | 2019-04-03 | Onxeo | Combination of a dbait molecule and a hdac inhibitor for treating cancer |
| WO2021148581A1 (en) | 2020-01-22 | 2021-07-29 | Onxeo | Novel dbait molecule and its use |
| US20250134952A1 (en) | 2021-09-20 | 2025-05-01 | Institut National de la Santé et de la Recherche Médicale | Methods for improving the efficacy of hdac inhibitor therapy and predicting the response to treatment with hdac inhibitor |
| CN119546293A (zh) | 2022-04-05 | 2025-02-28 | 国家癌症研究所Irccs-G·帕斯卡莱基金会 | Hdac抑制剂和他汀类药物的组合用于治疗胰腺癌 |
| WO2025026925A1 (en) | 2023-07-28 | 2025-02-06 | Ospedale San Raffaele S.R.L. | Gtf2i inhibitors and uses thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ219974A (en) * | 1986-04-22 | 1989-08-29 | Goedecke Ag | N-(2'-aminophenyl)-benzamide derivatives, process for their preparation and their use in the control of neoplastic diseases |
-
2000
- 2000-11-03 CA CA002386876A patent/CA2386876A1/en not_active Abandoned
- 2000-11-03 JP JP2001536131A patent/JP2003513912A/ja active Pending
- 2000-11-03 PL PL00355170A patent/PL355170A1/xx not_active Application Discontinuation
- 2000-11-03 WO PCT/US2000/030377 patent/WO2001034131A2/en not_active Application Discontinuation
- 2000-11-03 EP EP00978360A patent/EP1229916A2/en not_active Withdrawn
- 2000-11-03 AU AU15832/01A patent/AU1583201A/en not_active Abandoned
- 2000-11-03 HU HU0203153A patent/HUP0203153A3/hu unknown
- 2000-11-03 CN CN00815470A patent/CN1387438A/zh active Pending
- 2000-11-03 IL IL14936300A patent/IL149363A0/xx unknown
- 2000-11-03 NZ NZ518668A patent/NZ518668A/en unknown
- 2000-11-03 KR KR1020027005970A patent/KR20020060226A/ko not_active Withdrawn
- 2000-11-07 SV SV2000000212A patent/SV2001000212A/es not_active Application Discontinuation
- 2000-11-09 AR ARP000105899A patent/AR026400A1/es unknown
- 2000-11-09 GT GT200000194A patent/GT200000194A/es unknown
- 2000-11-09 UY UY26431A patent/UY26431A1/es not_active Application Discontinuation
- 2000-11-09 PA PA20008506201A patent/PA8506201A1/es unknown
- 2000-11-09 PE PE2000001196A patent/PE20011028A1/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| KR20020060226A (ko) | 2002-07-16 |
| CN1387438A (zh) | 2002-12-25 |
| HUP0203153A2 (hu) | 2003-01-28 |
| NZ518668A (en) | 2004-04-30 |
| WO2001034131A2 (en) | 2001-05-17 |
| AR026400A1 (es) | 2003-02-12 |
| HUP0203153A3 (en) | 2005-01-28 |
| PA8506201A1 (es) | 2002-12-11 |
| UY26431A1 (es) | 2000-12-29 |
| JP2003513912A (ja) | 2003-04-15 |
| PE20011028A1 (es) | 2001-10-12 |
| WO2001034131A3 (en) | 2002-05-10 |
| EP1229916A2 (en) | 2002-08-14 |
| SV2001000212A (es) | 2001-10-25 |
| PL355170A1 (en) | 2004-04-05 |
| IL149363A0 (en) | 2002-11-10 |
| CA2386876A1 (en) | 2001-05-17 |
| AU1583201A (en) | 2001-06-06 |
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