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GR990100345A - Composite liposomes for use against the aids virus and for the activation of memory lymphocytes - Google Patents

Composite liposomes for use against the aids virus and for the activation of memory lymphocytes

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Publication number
GR990100345A
GR990100345A GR990100345A GR990100345A GR990100345A GR 990100345 A GR990100345 A GR 990100345A GR 990100345 A GR990100345 A GR 990100345A GR 990100345 A GR990100345 A GR 990100345A GR 990100345 A GR990100345 A GR 990100345A
Authority
GR
Greece
Prior art keywords
liposomes
composite
activation
humans
immune system
Prior art date
Application number
GR990100345A
Other languages
Greek (el)
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Original Assignee
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by filed Critical
Publication of GR990100345A publication Critical patent/GR990100345A/en

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  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The invention refers to a concoction consisting of composite multilaminar liposomes. A synthetix polypeptide of aminoacid sequence according to the formula RKSIRIQRGPGRAF isbinded on the surface of the said liposomes, whereas their inside, may conatin any molecule with antigenic properties. The described concoction mediates between macrophages and T lympocytes, resulting in the inhibition of retroviral insertion in the cells whereas, at the same time activates the memory cells of the immune system against the contained antigen. The preparation of medicines with the above composition and their administration to humans with allow the prevention and the treatment of infections by the Human immunodeficiency Virus in humans, as well as the concurrent activation of the immune system in order, for example, to tret autoimmune diseases and other conditions.
GR990100345A 1999-10-06 1999-10-06 Composite liposomes for use against the aids virus and for the activation of memory lymphocytes GR990100345A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GR99100345 1999-10-06

Publications (1)

Publication Number Publication Date
GR990100345A true GR990100345A (en) 2001-06-29

Family

ID=10943939

Family Applications (1)

Application Number Title Priority Date Filing Date
GR990100345A GR990100345A (en) 1999-10-06 1999-10-06 Composite liposomes for use against the aids virus and for the activation of memory lymphocytes

Country Status (1)

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GR (1) GR990100345A (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH032195A (en) * 1989-05-29 1991-01-08 Nitto Denko Corp Peptide and protease inhibitor
WO1993022343A1 (en) * 1992-05-01 1993-11-11 The Rockfeller University Multiple antigen peptide system having adjuvant properties and vaccines prepared therefrom
US6180134B1 (en) * 1993-03-23 2001-01-30 Sequus Pharmaceuticals, Inc. Enhanced ciruclation effector composition and method

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH032195A (en) * 1989-05-29 1991-01-08 Nitto Denko Corp Peptide and protease inhibitor
WO1993022343A1 (en) * 1992-05-01 1993-11-11 The Rockfeller University Multiple antigen peptide system having adjuvant properties and vaccines prepared therefrom
US6180134B1 (en) * 1993-03-23 2001-01-30 Sequus Pharmaceuticals, Inc. Enhanced ciruclation effector composition and method

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; HATTORI, TOSHIO ET AL: "Peptides having partial sequence of human immunodeficiency virus protein gp120, and their use as protease inhibitors", XP002181122, retrieved from STN Database accession no. 115:78928 *
DEFOORT, JEAN PHILIPPE ET AL: "Macromolecular assemblage in the design of a synthetic AIDS vaccine", PROC. NATL. ACAD. SCI. U. S. A. (1992), 89(9), 3879-83, XP002181119 *
LOLEIT, MANUEL ET AL: "Conjugates of synthetic lymphocyte-activating lipopeptides with segments from HIV proteins induce protein-specific antibody formation", BIOL. CHEM. HOPPE-SEYLER (1990), 371(10), 967-75, XP001030865 *
WHITE, WENDY I. ET AL: "Antibody and cytotoxic T-lymphocyte responses to a single liposome-- -associated peptide antigen", VACCINE (1995), VOLUME DATE 1995, 13(12), 1111-22, XP002181121 *

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