GR980100096A - Νεα συνθεση βαλσαλαζιδης - Google Patents
Νεα συνθεση βαλσαλαζιδηςInfo
- Publication number
- GR980100096A GR980100096A GR980100096A GR980100096A GR980100096A GR 980100096 A GR980100096 A GR 980100096A GR 980100096 A GR980100096 A GR 980100096A GR 980100096 A GR980100096 A GR 980100096A GR 980100096 A GR980100096 A GR 980100096A
- Authority
- GR
- Greece
- Prior art keywords
- balsalazide
- new formulation
- formulation
- hydroxy
- density
- Prior art date
Links
- 238000009472 formulation Methods 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- 229960004168 balsalazide Drugs 0.000 title abstract 2
- IPOKCKJONYRRHP-FMQUCBEESA-N balsalazide Chemical compound C1=CC(C(=O)NCCC(=O)O)=CC=C1\N=N\C1=CC=C(O)C(C(O)=O)=C1 IPOKCKJONYRRHP-FMQUCBEESA-N 0.000 title 1
- 208000018522 Gastrointestinal disease Diseases 0.000 abstract 1
- JHDYSXXPQIFFJZ-UHFFFAOYSA-N chembl1834961 Chemical class C1=C(O)C(C(=O)O)=CC(N=NC=2C=CC=CC=2)=C1 JHDYSXXPQIFFJZ-UHFFFAOYSA-N 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
- -1 sodium balsalazide dihydrate Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/655—Azo (—N=N—), diazo (=N2), azoxy (>N—O—N< or N(=O)—N<), azido (—N3) or diazoamino (—N=N—N<) compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9700934A SE9700934D0 (sv) | 1997-03-14 | 1997-03-14 | New formulation |
Publications (1)
Publication Number | Publication Date |
---|---|
GR980100096A true GR980100096A (el) | 1998-11-30 |
Family
ID=20406161
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GR980100096A GR980100096A (el) | 1997-03-14 | 1998-03-06 | Νεα συνθεση βαλσαλαζιδης |
Country Status (15)
Country | Link |
---|---|
US (1) | US6197341B1 (el) |
EP (1) | EP1003524A1 (el) |
JP (1) | JP2001519782A (el) |
AU (1) | AU6430198A (el) |
BE (1) | BE1011837A5 (el) |
BR (1) | BR9808140A (el) |
CA (1) | CA2283297A1 (el) |
FR (1) | FR2760638A1 (el) |
GR (1) | GR980100096A (el) |
HU (1) | HUP0000850A3 (el) |
NL (1) | NL1008575C2 (el) |
NO (1) | NO994431D0 (el) |
PL (1) | PL335700A1 (el) |
SE (1) | SE9700934D0 (el) |
WO (1) | WO1998041212A1 (el) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE9700934D0 (sv) * | 1997-03-14 | 1997-03-14 | Astra Ab | New formulation |
JP5112595B2 (ja) * | 2000-08-29 | 2013-01-09 | バイオコン・リミテッド | 抗炎症活性および抗生物質活性を有する5−asa誘導体およびこれを用いて疾患を治療する方法 |
DK1642885T3 (da) * | 2000-08-29 | 2010-01-04 | Biocon Ltd | Anvendelse af et farmaceutisk præparat der indeholder et para-aminophenyl-eddikesyrederivat til behandling af inflammatoriske tilstande i mave-tarmkanalen |
US8048924B2 (en) * | 2001-08-29 | 2011-11-01 | Biocon Limited | Methods and compositions employing 4-aminophenylacetic acid compounds |
MY140707A (en) * | 2002-02-28 | 2010-01-15 | Mitsubishi Tanabe Pharma Corp | Process for preparing a phenylalanine derivative and intermediates thereof |
ZA200607435B (en) | 2004-02-06 | 2009-05-27 | Pharmatel Red Pty Ltd As The T | Use of aminosalicylates in diarrhoea-predominant irritable bowel syndrome |
US20080306029A1 (en) * | 2004-05-28 | 2008-12-11 | Salix Pharmaceuticals, Inc. | Prevention, Treatment, and Amelioration of Radiation Induced Enteritis |
CA2556373C (en) * | 2004-05-28 | 2012-09-04 | Salix Pharmaceuticals, Inc. | Prevention, treatment, and amelioration of radiation induced enteritis |
HUE028158T2 (en) | 2004-07-07 | 2016-12-28 | Biocon Ltd | Synthesis of bound immunoregulatory compounds |
US7741359B2 (en) * | 2005-05-27 | 2010-06-22 | Antibe Therapeutics Inc. | Hydrogen sulfide derivatives of non-steroidal anti-inflammatory drugs |
WO2006125293A1 (en) * | 2005-05-27 | 2006-11-30 | Antibe Therapeutics Inc. | Derivatives of 4- or 5-aminosalicylic acid |
US7498355B2 (en) * | 2005-05-27 | 2009-03-03 | Antibe Therapeutics Inc. | Derivatives of 4- or 5-aminosalicylic acid |
US20060270635A1 (en) * | 2005-05-27 | 2006-11-30 | Wallace John L | Derivatives of 4- or 5-aminosalicylic acid |
CN102670626A (zh) | 2005-08-24 | 2012-09-19 | 萨利克斯药品公司 | 巴柳氮制剂及其生产和应用 |
US8921344B2 (en) | 2006-11-03 | 2014-12-30 | Salix Pharmaceuticals, Inc. | Formulations and uses of 2-hydroxy-5-phenylazobenzoic acid derivatives |
US7452872B2 (en) * | 2005-08-24 | 2008-11-18 | Salix Pharmaceuticals, Inc. | Formulations and uses of 2-hydroxy-5-phenylazobenzoic acid derivatives |
CN101489986A (zh) * | 2006-06-06 | 2009-07-22 | 安泰碧治疗公司 | 曲美布汀和n-去甲基曲美布汀的盐 |
EP2563117B1 (en) | 2010-04-26 | 2018-02-21 | Salix Pharmaceuticals, Ltd. | Formulations and uses of 2-hydroxy-5-phenylazobenzoic acid derivatives for the treatment of males |
US12053447B2 (en) | 2019-06-25 | 2024-08-06 | NuBioPharma, LLC | Oral solution and powder to liquid compositions of balsalazide |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1981002671A1 (en) * | 1980-03-20 | 1981-10-01 | Ferring Farma Lab | Pharmaceutical composition and method for the treatment of colitis ulcerosa and crohn's disease by oral administration |
GB2080796A (en) * | 1980-07-21 | 1982-02-10 | Biorex Laboratories Ltd | 2-Hydroxy-5-phenylazobenzoic acid derivatives |
US5316772A (en) * | 1990-12-19 | 1994-05-31 | Solvay & Cie, S.A. (Societe Anonyme) | Bilayered oral pharmaceutical composition with pH dependent release |
WO1995018622A1 (en) * | 1994-01-07 | 1995-07-13 | Salix Pharmaceuticals, Inc. | Use of 2-hydroxy-5-phenylazobenzoic acid derivatives as colon cancer chemopreventative and chemotherapeutic agents |
WO1998041212A1 (en) * | 1997-03-14 | 1998-09-24 | Astra Aktiebolag (Publ) | New formulation |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4045429A (en) | 1970-03-06 | 1977-08-30 | Pharmacia Aktiebolag | 4-(4-Hydroxy- or acetoxy-3-carbomethoxyphenylazo)-benzenesulphonyl chloride |
BE791889A (fr) | 1971-11-26 | 1973-05-24 | Pharmacia Ab | Nouveaux derives de la pyridine |
US4412992A (en) | 1980-07-21 | 1983-11-01 | Biorex Laboratories Limited | 2-Hydroxy-5-phenylazobenzoic acid derivatives and method of treating ulcerative colitis therewith |
SE9003296L (sv) * | 1990-10-16 | 1992-04-17 | Kabi Pharmacia Ab | Foerfarande foer att formulera laekemedel |
-
1997
- 1997-03-14 SE SE9700934A patent/SE9700934D0/xx unknown
-
1998
- 1998-03-06 GR GR980100096A patent/GR980100096A/el unknown
- 1998-03-12 FR FR9803077A patent/FR2760638A1/fr not_active Withdrawn
- 1998-03-12 NL NL1008575A patent/NL1008575C2/nl not_active IP Right Cessation
- 1998-03-13 CA CA002283297A patent/CA2283297A1/en not_active Abandoned
- 1998-03-13 JP JP54042198A patent/JP2001519782A/ja active Pending
- 1998-03-13 BR BR9808140-3A patent/BR9808140A/pt not_active IP Right Cessation
- 1998-03-13 PL PL98335700A patent/PL335700A1/xx unknown
- 1998-03-13 HU HU00008500000850A patent/HUP0000850A3/hu unknown
- 1998-03-13 EP EP98909944A patent/EP1003524A1/en not_active Withdrawn
- 1998-03-13 AU AU64301/98A patent/AU6430198A/en not_active Abandoned
- 1998-03-13 WO PCT/SE1998/000455 patent/WO1998041212A1/en not_active Application Discontinuation
- 1998-03-13 BE BE9800201A patent/BE1011837A5/fr not_active IP Right Cessation
- 1998-05-14 US US09/068,823 patent/US6197341B1/en not_active Expired - Lifetime
-
1999
- 1999-09-13 NO NO994431A patent/NO994431D0/no unknown
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1981002671A1 (en) * | 1980-03-20 | 1981-10-01 | Ferring Farma Lab | Pharmaceutical composition and method for the treatment of colitis ulcerosa and crohn's disease by oral administration |
GB2080796A (en) * | 1980-07-21 | 1982-02-10 | Biorex Laboratories Ltd | 2-Hydroxy-5-phenylazobenzoic acid derivatives |
US5316772A (en) * | 1990-12-19 | 1994-05-31 | Solvay & Cie, S.A. (Societe Anonyme) | Bilayered oral pharmaceutical composition with pH dependent release |
WO1995018622A1 (en) * | 1994-01-07 | 1995-07-13 | Salix Pharmaceuticals, Inc. | Use of 2-hydroxy-5-phenylazobenzoic acid derivatives as colon cancer chemopreventative and chemotherapeutic agents |
WO1998041212A1 (en) * | 1997-03-14 | 1998-09-24 | Astra Aktiebolag (Publ) | New formulation |
Also Published As
Publication number | Publication date |
---|---|
SE9700934D0 (sv) | 1997-03-14 |
NO994431L (no) | 1999-09-13 |
EP1003524A1 (en) | 2000-05-31 |
HUP0000850A3 (en) | 2000-10-30 |
NL1008575C2 (nl) | 1999-09-10 |
WO1998041212A1 (en) | 1998-09-24 |
CA2283297A1 (en) | 1998-09-24 |
FR2760638A1 (fr) | 1998-09-18 |
AU6430198A (en) | 1998-10-12 |
JP2001519782A (ja) | 2001-10-23 |
NO994431D0 (no) | 1999-09-13 |
US6197341B1 (en) | 2001-03-06 |
PL335700A1 (en) | 2000-05-08 |
BE1011837A5 (fr) | 2000-02-01 |
HUP0000850A2 (hu) | 2000-09-28 |
NL1008575A1 (nl) | 1998-09-15 |
BR9808140A (pt) | 2000-03-28 |
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