[go: up one dir, main page]

GR900300066T1 - Guanidine derivatives having hypotensive activity, composition containing them, and process for obtaining them - Google Patents

Guanidine derivatives having hypotensive activity, composition containing them, and process for obtaining them

Info

Publication number
GR900300066T1
GR900300066T1 GR90300066T GR900300066T GR900300066T1 GR 900300066 T1 GR900300066 T1 GR 900300066T1 GR 90300066 T GR90300066 T GR 90300066T GR 900300066 T GR900300066 T GR 900300066T GR 900300066 T1 GR900300066 T1 GR 900300066T1
Authority
GR
Greece
Prior art keywords
obtaining
composition containing
guanidine derivatives
hypotensive activity
hypotensive
Prior art date
Application number
GR90300066T
Other languages
English (en)
Inventor
Monache Giuliano Delle
Monache Franco Delle
Bruno Botta
Castillo Stella Bonnevaux
Romulo Espinal
Luca Carlo De
Marco Carmignani
Original Assignee
Consiglio Nazionale Ricerche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Consiglio Nazionale Ricerche filed Critical Consiglio Nazionale Ricerche
Publication of GR900300066T1 publication Critical patent/GR900300066T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/12—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/04—Systems containing only non-condensed rings with a four-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GR90300066T 1988-02-24 1991-07-31 Guanidine derivatives having hypotensive activity, composition containing them, and process for obtaining them GR900300066T1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT47665/88A IT1219846B (it) 1988-02-24 1988-02-24 Nuovi derivati guandinici ad attivita' ipotensia,composizione che li contengono e relativo procedimento di estrazione e purificazione da materiale botanico

Publications (1)

Publication Number Publication Date
GR900300066T1 true GR900300066T1 (en) 1991-07-31

Family

ID=11261768

Family Applications (1)

Application Number Title Priority Date Filing Date
GR90300066T GR900300066T1 (en) 1988-02-24 1991-07-31 Guanidine derivatives having hypotensive activity, composition containing them, and process for obtaining them

Country Status (7)

Country Link
US (1) US5059624A (el)
EP (1) EP0330629A3 (el)
JP (1) JPH023661A (el)
DE (1) DE330629T1 (el)
ES (1) ES2013585A4 (el)
GR (1) GR900300066T1 (el)
IT (1) IT1219846B (el)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5344846A (en) * 1992-12-30 1994-09-06 The United States Of America As Represented By The Department Of Health And Human Services Compositions and methods for inhibiting deoxyhypusine synthase and the growth of cells
US5424447A (en) * 1993-07-07 1995-06-13 The Medical College Of Wisconsin Research Foundation, Inc. Heme binding compounds and use thereof
EP0749418B1 (en) * 1994-03-10 2000-08-30 G.D. Searle & Co. L-n6 -(1-iminoethyl)lysine derivatives useful as nitric oxide synthase inhibitors
US5514675A (en) * 1994-10-20 1996-05-07 Eli Lilly And Company Naphthyl bradykinin receptor antagonists
GB9511757D0 (en) * 1995-05-19 1995-08-02 Univ Strathclyde Agents for reducing weight
US5574059A (en) * 1995-10-27 1996-11-12 Cornell Research Foundation, Inc. Treating disorders mediated by vascular smooth muscle cell proliferation
FR2802769B1 (fr) * 1999-12-23 2004-01-16 Oreal Extrait de vegetal du genre leontopodium et compositions le contenant
JP2001199884A (ja) * 2000-01-21 2001-07-24 Seiwa Yakuhin Kk 鎮痛作用剤
JP2002363075A (ja) * 2001-06-05 2002-12-18 Kao Corp 高血圧症予防・治療剤
TW200403215A (en) * 2002-07-04 2004-03-01 Ajinomoto Kk Ultraviolet-absorbing composition
ITRM20020625A1 (it) * 2002-12-17 2004-06-18 Sigma Tau Ind Farmaceuti Derivati di guanidine variamente sostituite, loro uso come medicamenti ad attivita' antidiabetica e/o antiobesita'.
DE102008061247A1 (de) * 2008-12-10 2010-06-24 Christian-Albrechts-Universität Zu Kiel Inhibitoren der Dimethylarginin Dimethylaminohydrolase

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE625179A (el) *
US2734904A (en) * 1956-02-14 Xcxnhxc-nh
FR78162E (fr) * 1960-06-09 1962-06-15 Ciba Geigy Procédé de préparation de nouvelles alcoylène-imino-alcoyl-guanidines, de leurs sels et composés d'ammonium quaternaires
AT238219B (de) * 1961-11-23 1965-01-25 Farmaceutici Italia Verfahren zur Herstellung neuer mono- oder disubstituierter 2-Amino-äthyl-guanidin-verbindungen
CH433246A (de) * 1962-06-25 1967-04-15 Ciba Geigy Verfahren zur Herstellung von Guanidinverbindungen
SE321464B (el) * 1962-08-23 1970-03-09 Pharmacia Ab
US3202710A (en) * 1962-12-06 1965-08-24 Rexall Drug Chemical 1-(2-cycloalkyl-2-dilower alkylamino-ethyl) guanidines
US3459792A (en) * 1965-09-27 1969-08-05 Ciba Geigy Corp Cinnamyloxy guanidines and the salts thereof
US3475459A (en) * 1966-11-23 1969-10-28 Canadian Patents Dev Hordatine compounds and synthesis
HU178398B (en) * 1979-06-12 1982-04-28 Gyogyszerkutato Intezet Process for producing new agmatine derivatives of activity against haemagglutination
US4814007A (en) * 1986-01-16 1989-03-21 Henkel Corporation Recovery of precious metals
US4851441A (en) * 1986-06-26 1989-07-25 Harbor Branch Oceanographic Institution, Inc. Antiviral guanidine derivatives compositions and their methods of use

Also Published As

Publication number Publication date
ES2013585A4 (es) 1990-05-16
IT1219846B (it) 1990-05-24
IT8847665A0 (it) 1988-02-24
EP0330629A3 (en) 1990-10-31
US5059624A (en) 1991-10-22
DE330629T1 (de) 1990-04-12
JPH023661A (ja) 1990-01-09
EP0330629A2 (en) 1989-08-30

Similar Documents

Publication Publication Date Title
EP0201741A3 (en) Dipeptide derivatives, processes for preparing them, pharmaceutical composition and use
AU4584689A (en) Urea derivatives
IL83760A (en) 3-pyrazoliomethyl-3- cephem-4-carboxylate derivatives, process for the preparation thereof, and pharmacetuical compositions containing the same
DE3560511D1 (en) Pleuromutilin derivatives, process for their preparation and their use
HU900238D0 (en) Process for preparation of 1,4-disubstituted-piperidine-ketone derivatives
EP0169712A3 (en) New pyrimidine derivatives, processes for preparation thereof and composition containing the same
GR900300066T1 (en) Guanidine derivatives having hypotensive activity, composition containing them, and process for obtaining them
NZ223741A (en) Urea and cyanoguanidine derivatives; compositions
EP0168005A3 (en) Semicarbazide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same
GB2216121B (en) 6-alkenyl-1,3-dioxane-4-acetic acid derivatives
EG18544A (en) Six - membred heterocyclic derivatives of n', - substituted - n, n'-diacylhydrazines
ZA85487B (en) Azolyl-aryl-alkanol derivatives,processes for their preparation and their use
PT82061A (en) Process for preparing tricyclic compounds derived from 1,2-dihydronaftalene and heterocyclic analogues thereof
AR244661A1 (es) Procedimiento para la preparacion de urea.
ZA898784B (en) Renin-inhibiting urea derivatives of dipeptides,a process for the preparation thereof,agents containing these,and the use thereof
EP0253272A3 (en) Addition compounds, process for their preparation and their application
GR871209B (en) 2,3,4,5,67, - exhydro -2,7 methano -1,5 - benzoxazonin derivatives preparation method and medicaments containing said compound
EP0282895A3 (en) 2-oxa-isocephem compounds, compositions containing same and processes for preparing same
PH22967A (en) Bis-tert.-butylamino-substituted 1,3,5-triazine derivatives, medidaments containing these compounds and their use
ZA872721B (en) Compound,process and use
ZA896683B (en) Amide derivatives,process for their preparation and fungicidal compositions containing them
ZA851190B (en) Pleuromutilin derivatives,process for their preparation and their use
ZA851793B (en) Carboxyalkyldipeptide derivatives,a process for their preparation,agents containing them,and their use
GR890100646A (en) Preparation process of new 2-mithoxycarbonyl substituted n,n-d1-(trimethoxybenzoyl) piperazines
EP0344112A3 (en) Substituted bisacyloxynaphthacenes, and process for the preparation of tetrathiotetracenes