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GR900100798A - Μέ?οδος για την παρασκευή υδατικών διαλυμάτων μικτών μηκυλίων. - Google Patents

Μέ?οδος για την παρασκευή υδατικών διαλυμάτων μικτών μηκυλίων.

Info

Publication number
GR900100798A
GR900100798A GR900100798A GR900100798A GR900100798A GR 900100798 A GR900100798 A GR 900100798A GR 900100798 A GR900100798 A GR 900100798A GR 900100798 A GR900100798 A GR 900100798A GR 900100798 A GR900100798 A GR 900100798A
Authority
GR
Greece
Prior art keywords
water
active substances
solutions containing
soluble
mixted
Prior art date
Application number
GR900100798A
Other languages
English (en)
Inventor
Detlef Goritz
Michel Dr Heinrich
Georg Dr Rossling
Original Assignee
Berlin Und Bergkamen Schering
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6393595&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GR900100798(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Berlin Und Bergkamen Schering filed Critical Berlin Und Bergkamen Schering
Publication of GR900100798A publication Critical patent/GR900100798A/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Colloid Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Mushroom Cultivation (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

Περιγράφεται μία μέθοδος για την παρασκευή υδατικών διαλυμάτων μικτών μηκυλίων, που περιέχουν μικτά μηκύλια σχηματιζόμενα από λιπίδια και άλατα γαλενικών οξέων, στα οποία εφ' όσον είναι επιθυμητό διαλυτοποιούνται εντός ύδατος δυσδιάλυτες ή αδιάλυτες δραστικές ουσίες, η οποία χαρακτηρίζεται από το γεγονός, ότι παρασκευάζονται μείγματα από α) διαλύματα, που περιέχουν τα λιπίδια, τα ελεύθερα γαλενικά οξέα και σε δεδομένη περίπτωση τις εντός ύδατος δυσδιάλυτες ή αδιάλυτες δραστικές ουσίες εντός ενός υδατοδιαλυτού οργανικού διαλύτη και β) διαλύματα τα οποία σε σχέση προς τα γαλενικά οξέα περιέχουν 0,05 έως 3 ισοδύναμα βάσεων και σε δεδομένη περίπτωση ισοτονικά προσθετικά και/ή υδατοδιαλυτές δραστικές ουσίες, ότι απομακρύνεται ο οργανικός διαλύτης με υπερδιήθηση, λυοφιλισμό, απόσταξη εν κενώ και οσμωτική αναστροφή και ότι το λαμβανόμενο μείγμα αραιούται εφ' όσον είναι επιθυμητό με υδατική φάση. ω
GR900100798A 1989-11-13 1990-11-09 Μέ?οδος για την παρασκευή υδατικών διαλυμάτων μικτών μηκυλίων. GR900100798A (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3938030A DE3938030A1 (de) 1989-11-13 1989-11-13 Verfahren zur herstellung waessriger mischmicelloesungen

Publications (1)

Publication Number Publication Date
GR900100798A true GR900100798A (el) 1992-04-17

Family

ID=6393595

Family Applications (1)

Application Number Title Priority Date Filing Date
GR900100798A GR900100798A (el) 1989-11-13 1990-11-09 Μέ?οδος για την παρασκευή υδατικών διαλυμάτων μικτών μηκυλίων.

Country Status (15)

Country Link
EP (1) EP0453525B1 (el)
JP (1) JPH04505018A (el)
AT (1) ATE88632T1 (el)
AU (1) AU648050B2 (el)
CA (1) CA2029673C (el)
DE (2) DE3938030A1 (el)
DK (1) DK0453525T3 (el)
ES (1) ES2057592T3 (el)
FI (1) FI913235A0 (el)
GR (1) GR900100798A (el)
HU (1) HUT57577A (el)
IE (1) IE66507B1 (el)
NO (1) NO912748L (el)
PT (1) PT95853B (el)
WO (1) WO1991007170A1 (el)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6663885B1 (en) 1993-03-15 2003-12-16 A. Natterman & Cie Gmbh Aqueous liposome system and a method for the preparation of such a liposome system
JP2740153B2 (ja) * 1995-03-07 1998-04-15 エフ・ホフマン−ラ ロシユ アーゲー 混合ミセル
US9700866B2 (en) 2000-12-22 2017-07-11 Baxter International Inc. Surfactant systems for delivery of organic compounds
US20040256749A1 (en) * 2000-12-22 2004-12-23 Mahesh Chaubal Process for production of essentially solvent-free small particles
WO2008040799A2 (en) * 2006-10-06 2008-04-10 Boehringer Ingelheim International Gmbh Process for preparing instant forms of aqueous mixed micellar solutions as physiological buffer systems for use in the analysis of in vitro release
EP2201935B1 (en) * 2008-12-26 2020-07-08 Samyang Biopharmaceuticals Corporation Polymeric micelle composition containing a poorly soluble drug and preparation method of the same

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1289401A (fr) * 1953-03-07 1962-04-06 Merck & Co Inc Procédé de stabilisation de solutions huileuses de vitamines
EP0252004A1 (de) * 1986-06-26 1988-01-07 Ciba-Geigy Ag Pharmazeutische Zusammensetzungen für die parenterale Applikation
EP0280887A1 (de) * 1987-02-03 1988-09-07 F. Hoffmann-La Roche Ag Mischmicell-Lösungen mit nichtsteroidalen Entzündungshemmern

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1202370B (it) * 1976-07-12 1989-02-09 Hoffmann La Roche Soluzioni inietabili in cui l'atti vita' emolitica degli agenti di formazione di micelle naturali e' evitata mediante l'aggiunta di lipoidi e relativi prodotti

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1289401A (fr) * 1953-03-07 1962-04-06 Merck & Co Inc Procédé de stabilisation de solutions huileuses de vitamines
EP0252004A1 (de) * 1986-06-26 1988-01-07 Ciba-Geigy Ag Pharmazeutische Zusammensetzungen für die parenterale Applikation
EP0280887A1 (de) * 1987-02-03 1988-09-07 F. Hoffmann-La Roche Ag Mischmicell-Lösungen mit nichtsteroidalen Entzündungshemmern

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CLAIMS SEARCHED: ALL *

Also Published As

Publication number Publication date
NO912748D0 (no) 1991-07-12
IE66507B1 (en) 1996-01-10
EP0453525B1 (de) 1993-04-28
EP0453525A1 (de) 1991-10-30
WO1991007170A1 (de) 1991-05-30
HUT57577A (en) 1991-12-30
PT95853B (pt) 1999-02-26
FI913235A0 (fi) 1991-07-03
NO912748L (no) 1991-07-12
AU6658790A (en) 1991-05-16
CA2029673A1 (en) 1991-05-14
DE59001318D1 (de) 1993-06-03
DE3938030A1 (de) 1991-05-16
JPH04505018A (ja) 1992-09-03
CA2029673C (en) 2000-09-19
DK0453525T3 (da) 1993-08-23
PT95853A (pt) 1991-09-13
ATE88632T1 (de) 1993-05-15
AU648050B2 (en) 1994-04-14
IE904088A1 (en) 1991-05-22
ES2057592T3 (es) 1994-10-16
HU907430D0 (en) 1991-11-28

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