GR870661B - Process for preparing benzhydrylpiperazine derivatives - Google Patents
Process for preparing benzhydrylpiperazine derivativesInfo
- Publication number
- GR870661B GR870661B GR870661A GR870100661A GR870661B GR 870661 B GR870661 B GR 870661B GR 870661 A GR870661 A GR 870661A GR 870100661 A GR870100661 A GR 870100661A GR 870661 B GR870661 B GR 870661B
- Authority
- GR
- Greece
- Prior art keywords
- general formula
- preparing
- hydrogen
- alkyl
- derivatives
- Prior art date
Links
- 150000008640 diphenylmethylpiperazines Chemical class 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical group [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- VYFYYTLLBUKUHU-UHFFFAOYSA-N dopamine Chemical compound NCCC1=CC=C(O)C(O)=C1 VYFYYTLLBUKUHU-UHFFFAOYSA-N 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 229960003638 dopamine Drugs 0.000 abstract 1
- 230000003291 dopaminomimetic effect Effects 0.000 abstract 1
- 229910052736 halogen Chemical group 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 231100000053 low toxicity Toxicity 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003242 quaternary ammonium salts Chemical class 0.000 abstract 1
- 125000004953 trihalomethyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU861751A HU196196B (en) | 1986-04-28 | 1986-04-28 | Process for producing new benzhydryl-piperazine derivatives and pharmaceuticals comprising the compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR870661B true GR870661B (en) | 1987-09-02 |
Family
ID=10956008
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR870661A GR870661B (en) | 1986-04-28 | 1987-04-28 | Process for preparing benzhydrylpiperazine derivatives |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4868184A (el) |
| EP (1) | EP0243905B1 (el) |
| JP (1) | JPS62273970A (el) |
| AT (1) | ATE57378T1 (el) |
| AU (1) | AU594759B2 (el) |
| CA (1) | CA1298299C (el) |
| DE (1) | DE3765451D1 (el) |
| DK (1) | DK212387A (el) |
| ES (1) | ES2004410A6 (el) |
| FI (1) | FI85268C (el) |
| GR (1) | GR870661B (el) |
| HU (1) | HU196196B (el) |
| IL (1) | IL82354A (el) |
| ZA (1) | ZA873027B (el) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU196194B (en) * | 1986-04-28 | 1988-10-28 | Richter Gedeon Vegyeszet | Process for producing new 1-4 disubstituted piperazines and pharmaceuticals comprising the compounds |
| HU196195B (en) * | 1986-04-28 | 1988-10-28 | Richter Gedeon Vegyeszet | Process for producing 1,4-disubstituted piperazine derivatives and pharmaceuticals comprising the compounds |
| FR2601366B1 (fr) * | 1986-07-10 | 1988-11-25 | Andre Buzas | Derives de la benzhydryloxyethyl-piperazine, procedes d'obtention et de compositions pharmaceutiques les contenant. |
| US5028610A (en) * | 1987-03-18 | 1991-07-02 | Sankyo Company Limited | N-benzhydryl-substituted heterocyclic derivatives, their preparation and their use |
| DK178490D0 (da) * | 1990-07-26 | 1990-07-26 | Novo Nordisk As | 1,4-disubstituerede piperaziner |
| US5276035A (en) * | 1990-07-26 | 1994-01-04 | Novo Nordisk A/S | 1,4-disubstituted piperazines |
| FR2673182A1 (fr) * | 1991-02-22 | 1992-08-28 | Univ Caen | Piperazines n,n'-disubstituees, leur procede de preparation et leur application en therapeutique. |
| US5583665A (en) * | 1995-02-13 | 1996-12-10 | Eastman Kodak Company | Method and apparatus for performing color transformations using a reference image combined with a color tracer |
| US6304277B1 (en) | 1999-01-15 | 2001-10-16 | Colorcentric.Com, Inc. | Remote modification of digital images using scripts |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2899436A (en) * | 1959-08-11 | chjch | ||
| US2709169A (en) * | 1955-05-24 | X c chs | ||
| US2603435A (en) * | 1948-02-06 | 1952-07-15 | Earl G Metzler | Resilient mounting for airplane wings |
| US2861072A (en) * | 1952-07-19 | 1958-11-18 | Abbott Lab | Preparation of piperazine derivatives |
| GB837986A (en) * | 1956-07-10 | 1960-06-22 | Henri Morren | New piperazine derivatives and process for the preparation thereof |
| DE1062248B (de) * | 1956-07-10 | 1959-07-30 | Henri Morren | Verfahren zur Herstellung antiulceroes wirkender Piperazine |
| DE1470224B2 (de) * | 1961-10-02 | 1976-09-30 | G.D. Searle & Co., Chicago, Hl. (V.St.A.) | In 1-stellung substituierte 4- aminopiperazinderivate |
| DE1795375A1 (de) * | 1968-09-21 | 1972-01-05 | Boehringer Mannheim Gmbh | Basische AEther und Verfahren zur Herstellung derselben |
| FR2374318A1 (en) * | 1976-12-14 | 1978-07-13 | Gist Brocades Nv | 1-Benzhydryl:oxy-alkyl-4-phenylalkyl- or cinnamyl-piperazine derivs. - with dopaminergic, anticholinergic and antiparkinson activity (BE 14.6.78) |
| GB1545094A (en) * | 1976-12-14 | 1979-05-02 | Gist Brocades Nv | Piperazine derivatives |
| DE3600390A1 (de) * | 1986-01-09 | 1987-07-16 | Hoechst Ag | Diarylalkyl-substituierte alkylamine, verfahren zu ihrer herstellung, ihre verwendung sowie sie enthaltende arzneimittel |
| HU196194B (en) * | 1986-04-28 | 1988-10-28 | Richter Gedeon Vegyeszet | Process for producing new 1-4 disubstituted piperazines and pharmaceuticals comprising the compounds |
| HU196195B (en) * | 1986-04-28 | 1988-10-28 | Richter Gedeon Vegyeszet | Process for producing 1,4-disubstituted piperazine derivatives and pharmaceuticals comprising the compounds |
-
1986
- 1986-04-28 HU HU861751A patent/HU196196B/hu not_active IP Right Cessation
-
1987
- 1987-04-22 US US07/041,233 patent/US4868184A/en not_active Expired - Fee Related
- 1987-04-27 DK DK212387A patent/DK212387A/da not_active Application Discontinuation
- 1987-04-28 IL IL82354A patent/IL82354A/xx unknown
- 1987-04-28 AU AU72160/87A patent/AU594759B2/en not_active Ceased
- 1987-04-28 GR GR870661A patent/GR870661B/el unknown
- 1987-04-28 CA CA000535729A patent/CA1298299C/en not_active Expired - Lifetime
- 1987-04-28 EP EP87106034A patent/EP0243905B1/de not_active Expired - Lifetime
- 1987-04-28 ZA ZA873027A patent/ZA873027B/xx unknown
- 1987-04-28 FI FI871876A patent/FI85268C/fi not_active IP Right Cessation
- 1987-04-28 JP JP62106156A patent/JPS62273970A/ja active Pending
- 1987-04-28 ES ES8701262A patent/ES2004410A6/es not_active Expired
- 1987-04-28 DE DE8787106034T patent/DE3765451D1/de not_active Expired - Lifetime
- 1987-04-28 AT AT87106034T patent/ATE57378T1/de active
Also Published As
| Publication number | Publication date |
|---|---|
| FI871876A7 (fi) | 1987-10-29 |
| FI85268B (fi) | 1991-12-13 |
| CA1298299C (en) | 1992-03-31 |
| AU7216087A (en) | 1987-10-29 |
| IL82354A0 (en) | 1987-10-30 |
| HU196196B (en) | 1988-10-28 |
| FI85268C (fi) | 1992-03-25 |
| JPS62273970A (ja) | 1987-11-28 |
| EP0243905B1 (de) | 1990-10-10 |
| DE3765451D1 (de) | 1990-11-15 |
| HUT45039A (en) | 1988-05-30 |
| ATE57378T1 (de) | 1990-10-15 |
| DK212387A (da) | 1987-10-29 |
| ES2004410A6 (es) | 1989-01-01 |
| IL82354A (en) | 1991-09-16 |
| AU594759B2 (en) | 1990-03-15 |
| EP0243905A1 (de) | 1987-11-04 |
| DK212387D0 (da) | 1987-04-27 |
| ZA873027B (en) | 1988-03-30 |
| US4868184A (en) | 1989-09-19 |
| FI871876A0 (fi) | 1987-04-28 |
Similar Documents
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