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GR81625B - - Google Patents

Info

Publication number
GR81625B
GR81625B GR74908A GR840174908A GR81625B GR 81625 B GR81625 B GR 81625B GR 74908 A GR74908 A GR 74908A GR 840174908 A GR840174908 A GR 840174908A GR 81625 B GR81625 B GR 81625B
Authority
GR
Greece
Prior art keywords
beta
useful
lactam
compounds
debrominated
Prior art date
Application number
GR74908A
Other languages
English (en)
Inventor
D K Pirie
P D Weeks
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of GR81625B publication Critical patent/GR81625B/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Cephalosporin Compounds (AREA)
  • Steroid Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
GR74908A 1983-06-06 1984-06-04 GR81625B (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/501,731 US4468351A (en) 1983-06-06 1983-06-06 Process for debromination of dibromopenicillanic acid and derivatives

Publications (1)

Publication Number Publication Date
GR81625B true GR81625B (el) 1984-12-11

Family

ID=23994800

Family Applications (1)

Application Number Title Priority Date Filing Date
GR74908A GR81625B (el) 1983-06-06 1984-06-04

Country Status (22)

Country Link
US (1) US4468351A (el)
EP (1) EP0129360B1 (el)
JP (1) JPS608293A (el)
KR (1) KR870000324B1 (el)
AT (1) ATE29722T1 (el)
AU (1) AU551236B2 (el)
CA (1) CA1210388A (el)
DE (1) DE3466220D1 (el)
DK (1) DK275684A (el)
ES (1) ES533149A0 (el)
FI (1) FI82938C (el)
GR (1) GR81625B (el)
HU (1) HU193931B (el)
IE (1) IE57561B1 (el)
IL (1) IL72004A (el)
NO (1) NO162722C (el)
NZ (1) NZ208379A (el)
PH (1) PH20990A (el)
PL (1) PL143370B1 (el)
PT (1) PT78691A (el)
YU (1) YU44872B (el)
ZA (1) ZA844185B (el)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4588527A (en) * 1983-06-06 1986-05-13 Pfizer Inc. Process for preparing penicillanic acid 1,1-dioxide derivatives
EP0139048A1 (en) * 1983-10-18 1985-05-02 Gist-Brocades N.V. Process for the dehalogenation of 6,6-dibromopenicillanic acid 1,1-dioxide
US4596677A (en) * 1984-04-06 1986-06-24 Bristol-Myers Company Anhydropenicillin intermediates
ATE77821T1 (de) * 1986-04-10 1992-07-15 Leo Pharm Prod Ltd Verfahren zur herstellung von penicillansaeurederivaten.
US4885370A (en) * 1987-03-11 1989-12-05 Pfizer Inc. Synthetic method for indol-2(3H)-ones
GB8808701D0 (en) * 1988-04-13 1988-05-18 Erba Carlo Spa Beta-lactam derivatives
GB2343676A (en) 1998-11-12 2000-05-17 Merck & Co Inc Selective mono-debromination of polybromoalkyl aryl ketones
ES2336677T3 (es) * 2003-09-03 2010-04-15 Otsuka Chemical Co., Ltd. Proceso de produccion de compuestos de acido penicilanico.
CN102702228A (zh) * 2012-06-26 2012-10-03 齐鲁天和惠世制药有限公司 一种舒巴坦制备方法
CN104910184B (zh) * 2015-04-27 2017-03-29 齐鲁天和惠世制药有限公司 一种6,6‑二溴青霉烷酸的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4180506A (en) * 1978-01-18 1979-12-25 Rex Pratt 6β-Bromo penicillanic acid
EP0013617B1 (en) * 1979-01-10 1984-07-04 Beecham Group Plc Penicillin derivatives, process for their preparation and pharmaceutical compositions containing certain of these compounds
US4420426A (en) * 1979-03-05 1983-12-13 Pfizer Inc. 6-Alpha-halopenicillanic acid 1,1-dioxides
GB2051046B (en) * 1979-05-21 1984-03-28 Leo Pharm Prod Ltd Penicillanic acid derivatives
US4432970A (en) * 1979-11-23 1984-02-21 Pfizer Inc. 6-beta-Halopenicillanic acid 1,1-dioxides as beta-lactamase inhibitors
US4427678A (en) * 1982-01-11 1984-01-24 Pfizer Inc. 6-Aminomethylpenicillanic acid 1,1-dioxide derivatives as beta-lactamase inhibitors
PT76527B (en) * 1982-04-19 1985-12-09 Gist Brocades Nv A process for the preparation of penicillanic acid 1,1-dioxide and derivatives thereof

Also Published As

Publication number Publication date
EP0129360A1 (en) 1984-12-27
HUT34204A (en) 1985-02-28
JPH0342277B2 (el) 1991-06-26
PL143370B1 (en) 1988-02-29
CA1210388A (en) 1986-08-26
NO842250L (no) 1984-12-07
IL72004A (en) 1988-07-31
NO162722B (no) 1989-10-30
DE3466220D1 (en) 1987-10-22
YU97284A (en) 1986-10-31
PH20990A (en) 1987-06-18
ATE29722T1 (de) 1987-10-15
IL72004A0 (en) 1984-10-31
FI82938C (fi) 1991-05-10
FI82938B (fi) 1991-01-31
IE841392L (en) 1984-12-06
ES8602807A1 (es) 1985-12-01
ZA844185B (en) 1986-01-29
ES533149A0 (es) 1985-12-01
KR850000452A (ko) 1985-02-27
AU2907984A (en) 1984-12-13
IE57561B1 (en) 1992-12-16
HU193931B (en) 1987-12-28
FI842253A0 (fi) 1984-06-05
PT78691A (en) 1984-07-01
KR870000324B1 (ko) 1987-02-27
DK275684A (da) 1984-12-07
PL248046A1 (en) 1985-10-22
AU551236B2 (en) 1986-04-24
NZ208379A (en) 1987-05-29
US4468351A (en) 1984-08-28
JPS608293A (ja) 1985-01-17
EP0129360B1 (en) 1987-09-16
YU44872B (en) 1991-04-30
NO162722C (no) 1990-02-07
DK275684D0 (da) 1984-06-04
FI842253A (fi) 1984-12-07

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