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GR75367B - - Google Patents

Info

Publication number
GR75367B
GR75367B GR66351A GR810166351A GR75367B GR 75367 B GR75367 B GR 75367B GR 66351 A GR66351 A GR 66351A GR 810166351 A GR810166351 A GR 810166351A GR 75367 B GR75367 B GR 75367B
Authority
GR
Greece
Prior art keywords
layer
active agent
free
supporting ring
active
Prior art date
Application number
GR66351A
Other languages
English (en)
Inventor
Ingfried Dr Zimmermann
Fred Windt
Hans-Jurgen Reck
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of GR75367B publication Critical patent/GR75367B/el

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F6/00Contraceptive devices; Pessaries; Applicators therefor
    • A61F6/06Contraceptive devices; Pessaries; Applicators therefor for use by females
    • A61F6/08Pessaries, i.e. devices worn in the vagina to support the uterus, remedy a malposition or prevent conception, e.g. combined with devices protecting against contagion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Reproductive Health (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Vascular Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Anesthesiology (AREA)
  • Urology & Nephrology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Absorbent Articles And Supports Therefor (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Control And Safety Of Cranes (AREA)
  • General Induction Heating (AREA)
GR66351A 1980-10-28 1981-10-23 GR75367B (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803040978 DE3040978A1 (de) 1980-10-28 1980-10-28 Vaginalring

Publications (1)

Publication Number Publication Date
GR75367B true GR75367B (el) 1984-07-13

Family

ID=6115593

Family Applications (1)

Application Number Title Priority Date Filing Date
GR66351A GR75367B (el) 1980-10-28 1981-10-23

Country Status (26)

Country Link
US (1) US4822616A (el)
EP (1) EP0050867B1 (el)
JP (2) JPS5799954A (el)
AT (1) ATE31875T1 (el)
AU (1) AU7670981A (el)
BG (1) BG42182A3 (el)
CA (1) CA1165239A (el)
CS (1) CS253564B2 (el)
DD (1) DD201645A5 (el)
DE (2) DE3040978A1 (el)
DK (1) DK151529C (el)
EG (1) EG15347A (el)
ES (2) ES8505538A1 (el)
FI (1) FI78389C (el)
GR (1) GR75367B (el)
HU (1) HU183646B (el)
IE (1) IE54581B1 (el)
IL (1) IL64139A (el)
NO (1) NO153753C (el)
PL (1) PL127941B1 (el)
PT (1) PT73886B (el)
RO (1) RO88674A (el)
SU (1) SU1440326A3 (el)
YU (1) YU252281A (el)
ZA (1) ZA817477B (el)
ZW (1) ZW26081A1 (el)

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US5295984A (en) 1989-12-07 1994-03-22 Ultrafem, Inc. Vaginal discharge collection device and intravaginal drug delivery system
AU1797592A (en) * 1991-04-12 1992-11-17 Upjohn Company, The Vaginal drug delivery device
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GB9326255D0 (en) * 1993-12-23 1994-02-23 Roussel Lab Ltd Medical device for the prevention and treatment of cancer
DE69616551T2 (de) * 1995-07-04 2002-05-29 Akzo Nobel N.V., Arnheim/Arnhem Ringförmige vorrichtung
GB9522403D0 (en) * 1995-11-01 1996-01-03 Hoechst Roussel Ltd Intravaginal drug delivery device
US6030375A (en) * 1996-03-29 2000-02-29 Iotek, Inc. Compressible vaginal insert and method for treating urogenital disorders
US5988169A (en) * 1996-03-29 1999-11-23 Iotek, Inc. Vaginal insert and method for treating urogenital disorders
US5816248A (en) * 1996-03-29 1998-10-06 Iotek, Inc. Channeled vaginal insert and method for treating urogenital disorders
AU732781B2 (en) 1996-07-03 2001-04-26 Ultrafem, Inc. Method and system for manufacturing elastomeric articles
US5972372A (en) * 1996-07-31 1999-10-26 The Population Council, Inc. Intravaginal rings with insertable drug-containing core
IL123813A0 (en) * 1997-04-11 1998-10-30 Akzo Nobel Nv Drug delivery system for two or more active substances
US6039968A (en) * 1997-06-24 2000-03-21 Hoechst Marion Roussel Intravaginal drug delivery device
AU748653B2 (en) 1998-05-01 2002-06-06 John F. Cline Method for injection molding manufacture of controlled release devices
AU2001286726B2 (en) 2000-08-24 2007-03-22 Sidney Lerner Non-hormonal vaginal contraceptive
DE60116520T2 (de) * 2000-10-10 2006-08-31 Microchips, Inc., Bedford Microchip-reservoir-vorrichtungen mit drahtloser übertragung von energie und daten
RU2302883C2 (ru) * 2001-08-31 2007-07-20 Шеринг Ой Система доставки лекарств
US7497855B2 (en) * 2002-09-04 2009-03-03 Microchips, Inc. Method and device for the controlled delivery of parathyroid hormone
US7357046B2 (en) 2002-12-16 2008-04-15 N. V. Organon Method for dissolution testing of a pharmaceutical delivery device
CA2523859C (en) * 2003-04-29 2011-08-02 The General Hospital Corporation Methods and devices for the sustained release of multiple drugs
TWI336627B (en) 2003-05-23 2011-02-01 Organon Nv Drug delivery system,and use and manufacturing method thereof
ATE434433T1 (de) 2004-03-24 2009-07-15 Organon Nv Arzneimittelabgabesystem auf basis von polyethylen-vinylacetat-copolymeren
US20080076975A1 (en) * 2005-01-25 2008-03-27 Microchips, Inc. Method and implantable device with reservoir array for pre-clinical in vivo testing
WO2006081279A2 (en) * 2005-01-25 2006-08-03 Microchips, Inc. Control of drug release by transient modification of local microenvironments
CN1899643B (zh) * 2005-07-20 2010-12-29 上海市计划生育科学研究所 含有抗雌激素和抗孕激素复合制剂的阴道环或宫内释药装置及其制药用途
US8399012B2 (en) * 2006-04-17 2013-03-19 Kimberly-Clark Worldwide, Inc. Degradable therapeutic delivery device
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CN102098991B (zh) 2008-02-04 2014-10-22 特卫华妇女健康有限公司 包含孕酮的一体式阴道环以及其制备方法
US20100040671A1 (en) * 2008-08-12 2010-02-18 Ahmed Salah U Intravaginal Devices With a Rigid Support, Methods of Making, and Uses Thereof
US8420153B2 (en) * 2008-09-19 2013-04-16 Mentor Worldwide Llc Coating with antimicrobial agents
US8419793B2 (en) * 2008-09-19 2013-04-16 Mentor Worldwide Llc Coating with antimicrobial agents
ES2921527T3 (es) 2009-06-03 2022-08-29 Forsight Vision5 Inc Administración de fármaco en segmento anterior
AU2010274946B2 (en) 2009-07-21 2013-09-12 The Population Council, Inc. Multi-layered gradient vaginal ring
EA201290972A1 (ru) 2010-05-05 2013-08-30 Тева Вимен'С Хелс, Инк. Способы уменьшения симптомов у субъектов с применением лекарственных форм для однократного введения с постепенно снижающимися скоростями высвобождения
US8580294B2 (en) 2010-10-19 2013-11-12 International Partnership For Microbicides Platinum-catalyzed intravaginal rings
WO2012121811A1 (en) 2011-03-04 2012-09-13 Arstat, Inc. Treatment of excessive menstrual blood loss by intravaginal administration of low doses of antifibronlytic or hemostatic agent
WO2012121767A1 (en) 2011-03-09 2012-09-13 Arstat, Inc. Treatment of uterine fibroids by intravaginal administration of a low dose of selective progesterone receptor modulator (sprm), anti-progestin, or anti-progestational agent
WO2012121778A1 (en) 2011-03-10 2012-09-13 Arstat, Inc. Treatment of endometriosis by intravaginal administration of selective progesterone receptor modulator (sprm), anti-progestin, or anti-progestational agent
DE202012012761U1 (de) 2011-04-07 2013-10-29 Arstat, Inc. Mit Arzneimittel versehene intravaginale Vorrichtung und pharmazeutische Zusammensetzung zur Behandlung von Menstruationsschmerzen und übermäßigem Menstruationsblutverlust
US9937335B2 (en) * 2011-06-06 2018-04-10 Oak Crest Institute Of Science Drug delivery device employing wicking release window
KR102071083B1 (ko) 2011-09-14 2020-01-29 포사이트 비젼5, 인크. 안내 삽입물 장치 및 방법
PT2782584T (pt) 2011-11-23 2021-09-02 Therapeuticsmd Inc Preparações e terapias de substituição para hormonoterapias naturais combinadas
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
EP2911623B1 (en) 2012-10-26 2019-08-14 Forsight Vision5, Inc. Ophthalmic system for sustained release of drug to eye
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
WO2015055789A1 (en) 2013-10-17 2015-04-23 Bayer Pharma Aktiengesellschaft INTRAVAGINAL USE OF 18-METHYL-15ß,16ß-METHYLENE-19-NOR-20-SPIROX-4-EN-3-ONES, INTRAVAGINAL RINGS COMPRISING 18-METHYL-15ß,16ß-METHYLENE-19-NOR-20-SPIROX-4-EN-3-ONES, AND USE THEREOF IN CONTRACEPTION
US10137031B2 (en) 2013-11-14 2018-11-27 International Partnership For Microbicides, Inc. Combination therapy intravaginal rings
US10596103B2 (en) 2013-12-11 2020-03-24 Merek Sharp & Dohme B.V. Drug delivery system for delivery of anti-virals
US10413504B2 (en) 2013-12-11 2019-09-17 Merck Sharp & Dohme Corp. Intravaginal ring drug delivery system
DE102014004388A1 (de) * 2014-03-26 2015-10-01 Angela Kayser Verfahren und System zum intravaginalen Verabreichen von Progesteron
US10206932B2 (en) 2014-05-22 2019-02-19 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20160296532A1 (en) 2015-04-13 2016-10-13 Forsight Vision5, Inc. Ocular Insert Composition of a Semi-Crystalline or Crystalline Pharmaceutically Active Agent
JP6898856B2 (ja) 2015-05-13 2021-07-07 バイエル・オーイュー 長時間作用型薬物送達装置および避妊におけるその使用
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
EP4129300A1 (en) * 2016-03-23 2023-02-08 The University of North Carolina at Chapel Hill Geometrically complex intravaginal rings, systems and methods of making the same
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
MX2018011705A (es) 2016-04-01 2019-06-10 Therapeuticsmd Inc Composicion farmaceutica de hormona esteroide.
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DE102017113166A1 (de) 2017-06-14 2018-12-20 Amw Gmbh Depotform zur Abgabe eines Östrogen-Wirkstoffs
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Also Published As

Publication number Publication date
ZA817477B (en) 1982-10-27
HU183646B (en) 1984-05-28
NO813625L (no) 1982-04-29
IL64139A0 (en) 1982-01-31
CA1165239A (en) 1984-04-10
CS253564B2 (en) 1987-11-12
FI813360L (fi) 1982-04-29
IE54581B1 (en) 1989-12-06
FI78389C (fi) 1989-08-10
IE812503L (en) 1982-04-28
ES527301A0 (es) 1985-06-16
PL233606A1 (el) 1982-06-21
AU7670981A (en) 1982-05-06
BG42182A3 (en) 1987-10-15
JPH048893Y2 (el) 1992-03-05
DE3040978A1 (de) 1982-05-27
ATE31875T1 (de) 1988-01-15
PT73886A (fr) 1981-11-01
DE3176606D1 (en) 1988-02-18
DK471481A (da) 1982-04-29
NO153753C (no) 1986-05-21
US4822616A (en) 1989-04-18
DK151529B (da) 1987-12-14
PT73886B (fr) 1983-01-25
NO153753B (no) 1986-02-10
JPS5799954A (en) 1982-06-21
YU252281A (en) 1984-04-30
PL127941B1 (en) 1983-12-31
FI78389B (fi) 1989-04-28
RO88674A (ro) 1986-06-30
ZW26081A1 (en) 1982-05-19
JPH0324119U (el) 1991-03-13
DD201645A5 (de) 1983-08-03
EP0050867B1 (en) 1988-01-13
ES8505538A1 (es) 1985-06-16
SU1440326A3 (ru) 1988-11-23
DK151529C (da) 1988-05-30
EG15347A (en) 1986-03-31
EP0050867A1 (en) 1982-05-05
IL64139A (en) 1985-07-31
ES261058U (es) 1982-05-01

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