GR32450B - Νεα μεθοδος παρασκευης ν - (υποκατεστημενων αμινοαλκυλο) - 2 - αλκοξυ - 5 - αλογονοβενζαμιδιων. - Google Patents
Νεα μεθοδος παρασκευης ν - (υποκατεστημενων αμινοαλκυλο) - 2 - αλκοξυ - 5 - αλογονοβενζαμιδιων.Info
- Publication number
- GR32450B GR32450B GR670132450A GR670132450A GR32450B GR 32450 B GR32450 B GR 32450B GR 670132450 A GR670132450 A GR 670132450A GR 670132450 A GR670132450 A GR 670132450A GR 32450 B GR32450 B GR 32450B
- Authority
- GR
- Greece
- Prior art keywords
- preparation
- alkoxy
- halogenovenzamids
- alcoxy
- new method
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
έα μέθοδος παρακσευής Ν-τριτοτ- αμινοαλκυλο-2-αλκοξυ -5-αλογονοβενζμιδίων έκ 2-αλκοξυ-5-αλογονοβενζονιτριλίων του γενικού τύπου : (Ι) νιτρίλια του τύπου (Ι) κατεργάζονται δι' αλκοόλης του τύπου R3-OH(ΙΙ) παρουσία καταλύτου. Διά της ανωτέρω ακτεργασίας λαμβάνεται άλας έστέρος ενός 2-αλκοξυ-5-αλογονοβενζιμιδικού οξεός. Τα λαβμανομένα βενζιμιδικά οξέα, κατεργάζονται διά τριτοταγούς αμίνης, οπότε λαμβάνεται άλας μιάς Ν-(υποκατεστ-αμινοαλκυλο)-2 ακοξυ-5- αλογονοβενζομιδίνης. Τα άλατα τάυτα δυναταινα μετατραπούν λίαν ευχερώς είς διάλατα των αντιστοίχων βενζαμιδινων.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP378966 | 1966-01-22 | ||
| JP379166 | 1966-01-22 | ||
| JP416366 | 1966-01-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR32450B true GR32450B (el) | 1967-07-05 |
Family
ID=27275970
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR670132450A GR32450B (el) | 1966-01-22 | 1967-01-18 | Νεα μεθοδος παρασκευης ν - (υποκατεστημενων αμινοαλκυλο) - 2 - αλκοξυ - 5 - αλογονοβενζαμιδιων. |
Country Status (13)
| Country | Link |
|---|---|
| AT (3) | AT277970B (el) |
| BE (1) | BE692670A (el) |
| BG (1) | BG15554A3 (el) |
| CH (1) | CH478095A (el) |
| DK (1) | DK132794C (el) |
| ES (1) | ES336000A1 (el) |
| FI (1) | FI51172C (el) |
| FR (1) | FR1510299A (el) |
| GB (1) | GB1170321A (el) |
| GR (1) | GR32450B (el) |
| IL (3) | IL35861A (el) |
| SE (1) | SE349024B (el) |
| YU (1) | YU32358B (el) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4210754A (en) | 1977-02-01 | 1980-07-01 | Hoffmann-La Roche Inc. | Morpholino containing benzamides |
| US4808624A (en) * | 1984-06-28 | 1989-02-28 | Bristol-Myers Company | Pharmacologically active substituted benzamides |
-
1967
- 1967-01-16 ES ES336000A patent/ES336000A1/es not_active Expired
- 1967-01-16 BE BE692670D patent/BE692670A/xx not_active IP Right Cessation
- 1967-01-18 FR FR91681A patent/FR1510299A/fr not_active Expired
- 1967-01-18 GR GR670132450A patent/GR32450B/el unknown
- 1967-01-19 GB GB2933/67A patent/GB1170321A/en not_active Expired
- 1967-01-20 FI FI670172A patent/FI51172C/fi active
- 1967-01-20 IL IL35861A patent/IL35861A/en unknown
- 1967-01-20 SE SE00881/67A patent/SE349024B/xx unknown
- 1967-01-20 IL IL27281A patent/IL27281A/en unknown
- 1967-01-20 AT AT00027/69A patent/AT277970B/de not_active IP Right Cessation
- 1967-01-20 AT AT00026/69A patent/AT277969B/de not_active IP Right Cessation
- 1967-01-20 DK DK35167*#A patent/DK132794C/da active
- 1967-01-20 IL IL35862A patent/IL35862A/en unknown
- 1967-01-20 AT AT00613/67A patent/AT277214B/de not_active IP Right Cessation
- 1967-01-20 YU YU0096/67A patent/YU32358B/xx unknown
- 1967-01-21 BG BG007434A patent/BG15554A3/bg unknown
- 1967-01-23 CH CH93467A patent/CH478095A/fr not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AT277970B (de) | 1970-01-12 |
| IL35862A (en) | 1971-05-26 |
| FI51172C (fi) | 1976-11-10 |
| IL35861A (en) | 1971-05-26 |
| IL27281A (en) | 1971-05-26 |
| AT277214B (de) | 1969-12-10 |
| BG15554A3 (bg) | 1972-05-20 |
| GB1170321A (en) | 1969-11-12 |
| YU32358B (en) | 1974-08-31 |
| FI51172B (el) | 1976-08-02 |
| BE692670A (el) | 1967-07-17 |
| FR1510299A (fr) | 1968-01-19 |
| AT277969B (de) | 1970-01-12 |
| DK132794C (da) | 1976-07-12 |
| SE349024B (el) | 1972-09-18 |
| ES336000A1 (es) | 1968-04-01 |
| YU9667A (en) | 1974-04-30 |
| DK132794B (da) | 1976-02-09 |
| CH478095A (fr) | 1969-09-15 |
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