[go: up one dir, main page]

GR3022774T3 - Novel vitamin d analogues. - Google Patents

Novel vitamin d analogues.

Info

Publication number
GR3022774T3
GR3022774T3 GR970400458T GR970400458T GR3022774T3 GR 3022774 T3 GR3022774 T3 GR 3022774T3 GR 970400458 T GR970400458 T GR 970400458T GR 970400458 T GR970400458 T GR 970400458T GR 3022774 T3 GR3022774 T3 GR 3022774T3
Authority
GR
Greece
Prior art keywords
pct
compounds
thiol
sec
date
Prior art date
Application number
GR970400458T
Other languages
English (en)
Inventor
Rensen Gunnar Grue-S
Erik Rytter Ottosen
Original Assignee
Leo Pharm Prod Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo Pharm Prod Ltd filed Critical Leo Pharm Prod Ltd
Publication of GR3022774T3 publication Critical patent/GR3022774T3/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nutrition Science (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GR970400458T 1992-12-23 1997-03-07 Novel vitamin d analogues. GR3022774T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929226877A GB9226877D0 (en) 1992-12-23 1992-12-23 Chemical compounds
PCT/DK1993/000425 WO1994014766A1 (en) 1992-12-23 1993-12-17 Novel vitamin d analogues

Publications (1)

Publication Number Publication Date
GR3022774T3 true GR3022774T3 (en) 1997-06-30

Family

ID=10727157

Family Applications (1)

Application Number Title Priority Date Filing Date
GR970400458T GR3022774T3 (en) 1992-12-23 1997-03-07 Novel vitamin d analogues.

Country Status (15)

Country Link
US (1) US5554599A (el)
EP (1) EP0675878B1 (el)
KR (1) KR100295977B1 (el)
AT (1) ATE148454T1 (el)
AU (1) AU668638B2 (el)
CA (1) CA2146775C (el)
DE (1) DE69307929T2 (el)
DK (1) DK0675878T3 (el)
ES (1) ES2098123T3 (el)
FI (1) FI108225B (el)
GB (1) GB9226877D0 (el)
GR (1) GR3022774T3 (el)
NZ (1) NZ259317A (el)
RU (1) RU2136660C1 (el)
WO (1) WO1994014766A1 (el)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5830885A (en) * 1992-03-12 1998-11-03 The Johns Hopkins University Antiproliferative vitamin D3 hybrids
US6407082B1 (en) * 1996-09-13 2002-06-18 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of a vitamin D compound
US20040167106A1 (en) * 1993-06-04 2004-08-26 Rodriguez Gustavo C. Prevention of ovarian cancer by administration of a Vitamin D compound
GB9314400D0 (en) * 1993-07-12 1993-08-25 Leo Pharm Prod Ltd Produktionsaktieselskab) chemical compounds
DK0755922T3 (da) * 1994-04-11 2000-11-13 Chugai Pharmaceutical Co Ltd 22-Thiavitamin D3-derivat
WO1997024126A1 (fr) * 1995-12-28 1997-07-10 Chugai Seiyaku Kabushiki Kaisha Inhibiteurs des metastases de tumeurs malignes
US6869940B2 (en) 1995-12-28 2005-03-22 Chugai Seiyaku Kabushiki Kaisha Malignant tumor metastasis inhibitors
US6511970B1 (en) 1996-09-13 2003-01-28 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of products that induce transforming growth factor-beta and/or apoptosis in the ovarian epithelium
US6028064A (en) 1996-09-13 2000-02-22 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of progestin products
US6765002B2 (en) 2000-03-21 2004-07-20 Gustavo Rodriguez Prevention of ovarian cancer by administration of products that induce transforming growth factor-β and/or apoptosis in the ovarian epithelium
US6034074A (en) 1996-09-13 2000-03-07 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of a Vitamin D compound
US6184398B1 (en) 1996-12-20 2001-02-06 Chugai Seiyaku Kabushiki Kaisha 16-ene-vitamin D derivatives
WO1998028266A1 (fr) 1996-12-20 1998-07-02 Chugai Seiyaku Kabushiki Kaisha Derives de vitamine d 16-ene
US20030220234A1 (en) * 1998-11-02 2003-11-27 Selvaraj Naicker Deuterated cyclosporine analogs and their use as immunodulating agents
ATE344039T1 (de) 1999-04-01 2006-11-15 Univ Johns Hopkins Nicht-calcemische, transkriptionell-aktive, schwefelhaltige analoga von 1-alpha, 25- dihydroxyvitamin d3 mit antiproliferativer wirkung
US6703380B2 (en) 1999-09-29 2004-03-09 Colotech A/S Prevention of cancer
ES2240159T3 (es) 1999-09-29 2005-10-16 Colotech A/S Prevencion del cancer colorrectal.
WO2001030751A2 (en) * 1999-10-25 2001-05-03 Strakan Limited USES OF 1,25-DIHYDROXY-5,6-trans VITAMIN D COMPOUNDS AND DERIVATIVES THEREOF
US20010044431A1 (en) * 2000-03-21 2001-11-22 Rodriguez Gustavo C. Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium
US7074777B2 (en) 2000-04-19 2006-07-11 Chugai Seiyaku Kabushiki Kaisha Vitamin D derivatives
AU6428001A (en) 2000-06-15 2001-12-24 Chugai Pharmaceutical Co Ltd Vitamin d derivatives
DE60231987D1 (de) * 2001-08-22 2009-05-28 Univ Johns Hopkins 24-schwefel-substituierte 1-alpha-25-dihydroxy-vitamin-d3-analogen
SI1436321T1 (sl) * 2001-10-19 2006-12-31 Isotechnika Inc Sinteza analogov ciklosporina
CA2488334C (en) 2002-06-13 2010-12-07 Johns Hopkins University 24-sulfoximine vitamin d3 compounds
CA2510228C (en) 2002-12-18 2012-10-30 Johns Hopkins University 25-so2-substituted analogs of 1.alpha.,25-dihydroxyvitamin d3
EA201691980A1 (ru) 2009-01-27 2017-07-31 БЕРГ ЭлЭлСи Способы уменьшения побочных эффектов, связанных с химиотерапией
KR101880032B1 (ko) 2009-08-14 2018-07-20 베르그 엘엘씨 탈모증 치료용 비타민 d3 및 이의 유사체들
CA2913543C (en) 2013-05-29 2024-01-09 Berg Llc Preventing or mitigating chemotherapy induced alopecia using vitamin d

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2631025B1 (fr) * 1988-05-04 1991-04-12 Ire Medgenix Sa Nouveaux derives de la vitamine d3 et application aux dosages des metabolites de la vitamine d3
GB8904153D0 (en) * 1989-02-23 1989-04-05 Leo Pharm Prod Ltd Chemical compounds
DK0755922T3 (da) * 1994-04-11 2000-11-13 Chugai Pharmaceutical Co Ltd 22-Thiavitamin D3-derivat

Also Published As

Publication number Publication date
DK0675878T3 (da) 1997-04-28
DE69307929T2 (de) 1997-09-04
CA2146775A1 (en) 1994-07-07
CA2146775C (en) 2005-06-28
FI108225B (fi) 2001-12-14
ATE148454T1 (de) 1997-02-15
EP0675878B1 (en) 1997-01-29
FI952972L (fi) 1995-06-16
EP0675878A1 (en) 1995-10-11
KR950703501A (ko) 1995-09-20
ES2098123T3 (es) 1997-04-16
GB9226877D0 (en) 1993-02-17
DE69307929D1 (de) 1997-03-13
KR100295977B1 (ko) 2001-11-14
AU668638B2 (en) 1996-05-09
US5554599A (en) 1996-09-10
WO1994014766A1 (en) 1994-07-07
NZ259317A (en) 1997-05-26
FI952972A0 (fi) 1995-06-16
RU95113480A (ru) 1997-03-20
AU5808794A (en) 1994-07-19
RU2136660C1 (ru) 1999-09-10

Similar Documents

Publication Publication Date Title
GR3022774T3 (en) Novel vitamin d analogues.
HU9200761D0 (en) Process for the production of amino guanidines
LV10456A (lv) Triazolpiridazina atvasinajumi to iegusanas panemiens un pielietojums
Bahrami et al. Direct conversion of thiols and disulfides into sulfonamides
HK1054373A1 (en) Vitamin d derivatives possessing a 22-oxa or 22-thia atom, a c17-side chain substituted by an acid, ester or amide group and a 16(17)-double bond
SU633479A3 (ru) Способ получени стильбеновых соединений
GR3025280T3 (en) Novel vitamin d analogues.
UA75598C2 (uk) Спосіб одержання анілінових сполук, проміжна сполука та її застосування
GB1077076A (en) Novel imidazole derivatives and a process for the manufacture thereof
KR840001922B1 (ko) 2-메르캅토에틸아민할로겐화 수소산염류의 제조방법
ES2095073T3 (es) Procedimiento para la fabricacion de derivados de acido cinamico.
FI86057C (fi) 2-bensyltio- eller 2-bensylsulfoxid-1- cyklopenten-1-karboxamider, foerfaranden foer deras framstaellning och deras anvaendning vid syntes av 4,5-trimetylen-4-isotiazolin-3-oner.
US2467895A (en) Piperazine derivatives and method of preparing the same
HU199113B (en) Process for production of new derivatives of 2,3-diamin-acryl-acid-nitril
ES8703825A1 (es) Un procedimiento para la preparacion de derivados del acido fenil nonatetraenoico
Mizuno et al. Reaction of thiolates with carbon monoxide
NZ335104A (en) Process for preparing hydroxamic acids from carboxylic acid intermediates for use as matrix metalloproteinase inhibitors
US5017725A (en) Preparation of addition salts of cysteamine with acids
AU598714B2 (en) Process for preparing substituted guanylthioureas
US3308132A (en) 6, 8-dithiooctanoyl amides and intermediates
AU6520698A (en) Process for producing 1-chlorocarbonyl-4-piperidinopiperidine or hydrochloride thereof
ES8200092A1 (es) Procedimiento para la sintesis de esteres de la n-(4'hidro- xifenil) acetamida con acidos 5-benzoil-1-metilpirrol-2-ace-tico
IE49932B1 (en) Synthesis of 2-isopropylamino-pyrimidine
CA1135267A (en) Oxidation of alpha-alkylated, benzyl-substituted 2-thiopyridine 1-oxides
SU1216183A1 (ru) Способ получени ,цис,цис-3-тиа-1,4-пентадиен-1,5-дикарбоновой кислоты или ее динатриевой соли