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GR3022546T3 - Inositol phosphate analogues as calcium-antagonistic substances - Google Patents

Inositol phosphate analogues as calcium-antagonistic substances

Info

Publication number
GR3022546T3
GR3022546T3 GR970400235T GR970400235T GR3022546T3 GR 3022546 T3 GR3022546 T3 GR 3022546T3 GR 970400235 T GR970400235 T GR 970400235T GR 970400235 T GR970400235 T GR 970400235T GR 3022546 T3 GR3022546 T3 GR 3022546T3
Authority
GR
Greece
Prior art keywords
calcium
inositol phosphate
phosphate analogues
antagonistic substances
antagonistic
Prior art date
Application number
GR970400235T
Other languages
Greek (el)
English (en)
Inventor
Werner Dr Schiebler
Elke Deckert
Eric Dreef
D Marel Geijs Dr V
Boom Jacques Prof Von
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of GR3022546T3 publication Critical patent/GR3022546T3/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • C07F9/4071Esters thereof the ester moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4081Esters with cycloaliphatic alcohols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/08Esters of oxyacids of phosphorus
    • C07F9/09Esters of phosphoric acids
    • C07F9/117Esters of phosphoric acids with cycloaliphatic alcohols

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
GR970400235T 1991-06-26 1997-02-12 Inositol phosphate analogues as calcium-antagonistic substances GR3022546T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP91110546 1991-06-26

Publications (1)

Publication Number Publication Date
GR3022546T3 true GR3022546T3 (en) 1997-05-31

Family

ID=8206868

Family Applications (1)

Application Number Title Priority Date Filing Date
GR970400235T GR3022546T3 (en) 1991-06-26 1997-02-12 Inositol phosphate analogues as calcium-antagonistic substances

Country Status (11)

Country Link
US (1) US5395828A (da)
EP (1) EP0520372B1 (da)
JP (1) JP3161813B2 (da)
KR (1) KR930000527A (da)
AT (1) ATE145911T1 (da)
CA (1) CA2072303A1 (da)
DE (1) DE69215588T2 (da)
DK (1) DK0520372T3 (da)
ES (1) ES2095985T3 (da)
GR (1) GR3022546T3 (da)
HU (2) HUT64081A (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996000586A2 (en) * 1994-06-30 1996-01-11 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Methods for treating cell proliferative disorders by modulating signal transduction
US6953781B2 (en) 2000-05-12 2005-10-11 Rodaris Pharmaceuticals Limited Compounds and their uses
US6939857B2 (en) 2000-05-12 2005-09-06 Rodaris Pharmaceuticals Limited Compounds and their uses
US6759390B2 (en) 2000-05-12 2004-07-06 Manuel Martin-Lomas Compounds and their uses
US6716826B2 (en) 2000-05-12 2004-04-06 Rodaris Pharmaceuticals Limited Compounds and their uses
EP1331932B1 (en) * 2000-11-09 2007-04-04 Contrimmune Biotechnology Inc. Use of xestospongin c for treating or preventing hiv infection

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4515722A (en) * 1982-03-30 1985-05-07 Merck & Co., Inc. Phosphatidyl inositol analogs useful as anti-inflammatory/analgesic agents
US4952717A (en) * 1986-03-11 1990-08-28 Mitsui Toatsu Chemicals, Incorporated Myoinositol derivatives and preparation process thereof
SE8605063D0 (sv) * 1986-11-26 1986-11-26 Matti Siren Derivatives of cyclohexane

Also Published As

Publication number Publication date
JPH05213975A (ja) 1993-08-24
KR930000527A (ko) 1993-01-15
HU9202103D0 (en) 1992-10-28
HUT64081A (en) 1993-11-29
HU211491A9 (en) 1995-11-28
US5395828A (en) 1995-03-07
DK0520372T3 (da) 1997-05-12
DE69215588T2 (de) 1997-05-15
JP3161813B2 (ja) 2001-04-25
DE69215588D1 (de) 1997-01-16
ES2095985T3 (es) 1997-03-01
ATE145911T1 (de) 1996-12-15
EP0520372A1 (en) 1992-12-30
EP0520372B1 (en) 1996-12-04
CA2072303A1 (en) 1992-12-27

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