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GR1003521B - Methods of use of fluoroquinolone compounds against gram positive pathogenic bacteria - Google Patents

Methods of use of fluoroquinolone compounds against gram positive pathogenic bacteria

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Publication number
GR1003521B
GR1003521B GR990100321A GR990100321A GR1003521B GR 1003521 B GR1003521 B GR 1003521B GR 990100321 A GR990100321 A GR 990100321A GR 990100321 A GR990100321 A GR 990100321A GR 1003521 B GR1003521 B GR 1003521B
Authority
GR
Greece
Prior art keywords
pathogenic bacteria
methods
gram positive
against gram
compounds against
Prior art date
Application number
GR990100321A
Other languages
Greek (el)
Inventor
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of GR1003521B publication Critical patent/GR1003521B/en

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Abstract

This invention relates, in part, to newly identified methods of using quinolone antibiotics, particularly a gemifloxacin compound against certain pathogenic bacteria, such as bacteria selected from the group consisting of : Streptococsus pneumoniae, Enterococcus faecalis, Enterococcus faecium, Staphylococcus aureus and Staphylococcus epidermidis.
GR990100321A 1999-09-23 1999-09-23 Methods of use of fluoroquinolone compounds against gram positive pathogenic bacteria GR1003521B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GR99100321 1999-09-23

Publications (1)

Publication Number Publication Date
GR1003521B true GR1003521B (en) 2001-01-22

Family

ID=10943923

Family Applications (1)

Application Number Title Priority Date Filing Date
GR990100321A GR1003521B (en) 1999-09-23 1999-09-23 Methods of use of fluoroquinolone compounds against gram positive pathogenic bacteria

Country Status (1)

Country Link
GR (1) GR1003521B (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0688772A1 (en) * 1994-06-16 1995-12-27 LG Chemical Limited Novel quinoline carboxylic acid derivatives having 7-(4-amino-methyl-3-oxime) pyrrolidine substituents and processes for their preparation
WO1998042705A1 (en) * 1997-03-21 1998-10-01 Lg Chemical Ltd. Salt of naphthyridine carboxylic acid derivative

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0688772A1 (en) * 1994-06-16 1995-12-27 LG Chemical Limited Novel quinoline carboxylic acid derivatives having 7-(4-amino-methyl-3-oxime) pyrrolidine substituents and processes for their preparation
WO1998042705A1 (en) * 1997-03-21 1998-10-01 Lg Chemical Ltd. Salt of naphthyridine carboxylic acid derivative

Non-Patent Citations (17)

* Cited by examiner, † Cited by third party
Title
BOSWELL ET AL.: "The comparative in vitro activity of gemifloxacin, a novel fluoroquinolone", J. ANTIMICROBIAL CHEMOTHER., vol. 44, no. suppl. A, July 1999 (1999-07-01), pages 132, XP000911941 *
CORMICAN ET AL.: "Antimicrobial activity and spectrum of LB20304, a new fluoronaphthyridone", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, vol. 41, no. 1, January 1997 (1997-01-01), pages 204 - 211, XP000911943 *
CORMICAN ET AL.: "Comparative antimicrobial and spectrum activity of LB20304a, a new fluorinated naphthoquinone compound", ABSTRACT 36TH INTERSCIENCE CONFERENCE ON ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, vol. 36, 15 September 1996 (1996-09-15) - 18 September 1996 (1996-09-18), new orleans, louisana, pages 109, XP000861831 *
ERWIN ET AL.: "Studies to establish quality control ranges for SB-265805 (LB20304) when using National Committee for laboratory standards antimicrobial susceptibility test methods", J. CLIN. MICROBIAOL., vol. 37, no. 1, January 1999 (1999-01-01), pages 279 - 280, XP000861920 *
FINLAY ET AL.: "SB-265805 (LB20304a): use of the Etest to determine the minimum inhibitory concentration against 378 clinical isolates", ABSTRACT 38TH INTERSCIENCE CONFERENCE ON ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, vol. 38, 1998, san diego, california, pages 257, XP000861828 *
FIRZOV ET AL.: "Antistaphylococcal effects of gemifloxacin and comparator quinolones in an in vitro dynamic model", J. ANTIMICROBIAL CHEMOTHER., vol. 44, no. suppl.A, July 1999 (1999-07-01), pages 126, XP000911978 *
HARDY ET AL.: "comparative in vitro activity of gemifloxacin, moxifloxycin, trovafloxacin, sparfloxacin, grepafloxacin, ofloxacin, ciprofloxacin and other antimicrobial agenst against bloodstream isolates of Gram positive Cocci", J. ANTIMICROBIAL CHEMOTHER., vol. 44, no. suppl. A, July 1999 (1999-07-01), pages 146, XP000911942 *
HONG ET AL.: "Novel fluoroquinolone antibacterial agents containing oxime-substituted (aminomethyl) pyrrolidine; Synthesis and antibatcerial activity of 7-(4-(aminomethyl)-3-(methoxyimino)pyrrolidin-1-yl)- 1-cyclopropyl-6fluoro-4-oxo-1,4-dihydro[1,8]naphathyridine- 3-carboxylic acid (LB20304)", J. MED. CHEM., vol. 40, no. 22, 24 October 1994 (1994-10-24), pages 3584 - 3593, XP000911756 *
JOHNSON ET AL.: "Anti-Streptococcal activity of SB265805 (LB20304), a novel fluoronaphthyridone, compared with five other compounds, including quality control guidelines", DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, vol. 33, no. 2, February 1999 (1999-02-01), pages 87 - 91, XP000911956 *
KIM ET AL.: "In vitro activities of LB20304, a new fluoroquinolone", ARCH. PHARMACAL RES., vol. 19, no. 1, 1996, pages 52 - 59, XP000911954 *
KIM ET AL.: "Synthesis and antibacterial activities of LB20304: a new fluoronaphthyridone antibiotic containing novel oxime functionalized pyrrolidine", 35TH INTERNATIONAL CONFERENCE ON ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 17 September 1995 (1995-09-17) - 20 September 1995 (1995-09-20), san francisco, pages 148, XP002146747 *
KING ET AL.: "The comparative in vitro activity of gemifloxacin, a new fluoroquinolone against selected clinical isolates", J. ANTIMICROBIAL CHEMOTHER., vol. 44, no. suppl. A, July 1999 (1999-07-01), pages 147, XP000911926 *
MARCO ET AL.: "Antimicrobial activity of LB20304, a fluoronaphthyridone, tested against anaerobic bacteria", J. ANTIMICROBIAL CHEMOTHER., vol. 40, no. 4, 1997, pages 605 - 607, XP000911923 *
MORRISSEY ET AL.: "The bactericidal activity of gemifloxacin and other fluoroquinolones against S. pneumoniae", J. ANTIMICROBIOL. CHEMOTHER., vol. 44, no. suppl. A, July 1999 (1999-07-01), pages 147, XP000911924 *
OH ET AL.: "In vitro and in vivo antibacterial activities of LB20304a, a new fluoronaphthyridone", ANTIMICROBIAL AGENTS CHEMOTHER., vol. 40, no. 6, June 1996 (1996-06-01), pages 1564 - 1568, XP000911979 *
PAECK ET AL.: "Bactericidal activities of LB20304, a new fluoroquinolone", ARCH. PHARMACAL RES., vol. 19, no. 4, 1996, pages 317 - 320, XP000911955 *
PAECK ET AL.: "SB-265805 (LB20304a): In vitro antibacterial activity and spectrum", ABSTRACT 38TH INTERSCIENCE CONFERENCE ON ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, vol. 38, 24 September 1998 (1998-09-24) - 27 September 1998 (1998-09-27), san diego, california, pages 255, XP000861826 *

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