GEP20002030B - Diastereoselective Synthesis of Nucleosides - Google Patents
Diastereoselective Synthesis of NucleosidesInfo
- Publication number
- GEP20002030B GEP20002030B GEAP19922642A GEAP1992002642A GEP20002030B GE P20002030 B GEP20002030 B GE P20002030B GE AP19922642 A GEAP19922642 A GE AP19922642A GE AP1992002642 A GEAP1992002642 A GE AP1992002642A GE P20002030 B GEP20002030 B GE P20002030B
- Authority
- GE
- Georgia
- Prior art keywords
- nucleosides
- glycosylating
- diastereoselective synthesis
- base
- chemistry
- Prior art date
Links
- 239000002777 nucleoside Substances 0.000 title abstract 2
- 230000015572 biosynthetic process Effects 0.000 title 1
- 125000003835 nucleoside group Chemical group 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- 230000001279 glycosylating effect Effects 0.000 abstract 2
- WNXJIVFYUVYPPR-UHFFFAOYSA-N 1,3-dioxolane Chemical class C1COCO1 WNXJIVFYUVYPPR-UHFFFAOYSA-N 0.000 abstract 1
- 150000004865 1,3-dithiolanes Chemical class 0.000 abstract 1
- WJJSZTJGFCFNKI-UHFFFAOYSA-N 1,3-oxathiolane Chemical class C1CSCO1 WJJSZTJGFCFNKI-UHFFFAOYSA-N 0.000 abstract 1
- KDCGOANMDULRCW-UHFFFAOYSA-N Purine Natural products N1=CNC2=NC=NC2=C1 KDCGOANMDULRCW-UHFFFAOYSA-N 0.000 abstract 1
- CZPWVGJYEJSRLH-UHFFFAOYSA-N Pyrimidine Chemical compound C1=CN=CN=C1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 abstract 1
- 230000000840 anti-viral effect Effects 0.000 abstract 1
- 229940127073 nucleoside analogue Drugs 0.000 abstract 1
- IGFXRKMLLMBKSA-UHFFFAOYSA-N purine Chemical compound N1=C[N]C2=NC=NC2=C1 IGFXRKMLLMBKSA-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Plural Heterocyclic Compounds (AREA)
Abstract
1. Technical Result Simplification of the technological process and intensification of antiviral activity. 2. Essence A method for preparing optically active cis-nucleosides (1,3-oxathiolanes, 2,4-dioxolanes and 1,3-dithiolanes), nucleoside analogues and derivatives of the formula (I) (where R1, R2 W and X are presented in the description) comprising glycosylating the desired base with sugar and glycosylating the desired purine or pyrimidine base or derivative thereof with an intermediate. 3. Field of Application Chemistry, in particular organic chemistry. 5 ind. cl., and 28 dep. cl.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GEAP19922642A GEP20002030B (en) | 1992-05-21 | 1992-05-21 | Diastereoselective Synthesis of Nucleosides |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GEAP19922642A GEP20002030B (en) | 1992-05-21 | 1992-05-21 | Diastereoselective Synthesis of Nucleosides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GEP20002030B true GEP20002030B (en) | 2000-04-10 |
Family
ID=82787011
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GEAP19922642A GEP20002030B (en) | 1992-05-21 | 1992-05-21 | Diastereoselective Synthesis of Nucleosides |
Country Status (1)
| Country | Link |
|---|---|
| GE (1) | GEP20002030B (en) |
-
1992
- 1992-05-21 GE GEAP19922642A patent/GEP20002030B/en unknown
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