GB983122A - Pharmaceutically active amide - Google Patents
Pharmaceutically active amideInfo
- Publication number
- GB983122A GB983122A GB2587562A GB2587562A GB983122A GB 983122 A GB983122 A GB 983122A GB 2587562 A GB2587562 A GB 2587562A GB 2587562 A GB2587562 A GB 2587562A GB 983122 A GB983122 A GB 983122A
- Authority
- GB
- United Kingdom
- Prior art keywords
- tetrahydrofurfuryl
- reacting
- amidophenoxyacetate
- solutions
- pharmaceutically active
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/10—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/12—Radicals substituted by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention comprises tetrahydrofurfuryl-2-amidophenoxyacetate, and its preparation by (a) reacting salicylamide with a tetrahydrofurfuryl halogenoacetate or (b) reacting 2-amidophenoxyacetic acid with tetrahydrofurfuryl alcohol or a functional derivative thereof. The compound of the invention has pharmaceutical activity (see Division A5). Tetrahydrofurfuryl chloroacetate is prepared by reacting tetrahydrofurfuryl alcohol and chloroacetyl chloride in anhydrous chloroform.ALSO:Compositions having analgesic, antiphlogistic, anaesthetic and rubefacient activity comprise tetrahydrofurfuryl 2-amidophenoxyacetate in combination with a pharmaceutical carrier and may be in forms suitable for oral, topical, parenteral or rectal administration, for example as lozenges, powders, ointments, lotions, creams, sticks, spray-solutions, aerosols, solutions, emulsions or suppositories. Other anti-inflammatory agents may be present, for example salicylic acid derivatives, nicotinic esters or essential oils.
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2587562A GB983122A (en) | 1962-07-05 | 1962-07-05 | Pharmaceutically active amide |
BR15043863A BR6350438D0 (en) | 1962-07-05 | 1963-07-03 | PROCESS FOR THE PREPARATION OF 2-STARCH-PHENOXY-ACETATE OF TETRA-HYDROFURFURYL |
ES289620A ES289620A1 (en) | 1962-07-05 | 1963-07-04 | A procedure for the preparation of 2-amido-phenoxyacetate of tetrahidrofurfurilo (Machine-translation by Google Translate, not legally binding) |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2587562A GB983122A (en) | 1962-07-05 | 1962-07-05 | Pharmaceutically active amide |
Publications (1)
Publication Number | Publication Date |
---|---|
GB983122A true GB983122A (en) | 1965-02-10 |
Family
ID=10234798
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB2587562A Expired GB983122A (en) | 1962-07-05 | 1962-07-05 | Pharmaceutically active amide |
Country Status (3)
Country | Link |
---|---|
BR (1) | BR6350438D0 (en) |
ES (1) | ES289620A1 (en) |
GB (1) | GB983122A (en) |
-
1962
- 1962-07-05 GB GB2587562A patent/GB983122A/en not_active Expired
-
1963
- 1963-07-03 BR BR15043863A patent/BR6350438D0/en unknown
- 1963-07-04 ES ES289620A patent/ES289620A1/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
BR6350438D0 (en) | 1973-08-02 |
ES289620A1 (en) | 1963-10-16 |
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