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GB983122A - Pharmaceutically active amide - Google Patents

Pharmaceutically active amide

Info

Publication number
GB983122A
GB983122A GB2587562A GB2587562A GB983122A GB 983122 A GB983122 A GB 983122A GB 2587562 A GB2587562 A GB 2587562A GB 2587562 A GB2587562 A GB 2587562A GB 983122 A GB983122 A GB 983122A
Authority
GB
United Kingdom
Prior art keywords
tetrahydrofurfuryl
reacting
amidophenoxyacetate
solutions
pharmaceutically active
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2587562A
Inventor
Silvano Casadio
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Instituto de Angeli SpA
Original Assignee
Instituto de Angeli SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Instituto de Angeli SpA filed Critical Instituto de Angeli SpA
Priority to GB2587562A priority Critical patent/GB983122A/en
Priority to BR15043863A priority patent/BR6350438D0/en
Priority to ES289620A priority patent/ES289620A1/en
Publication of GB983122A publication Critical patent/GB983122A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/10Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/12Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention comprises tetrahydrofurfuryl-2-amidophenoxyacetate, and its preparation by (a) reacting salicylamide with a tetrahydrofurfuryl halogenoacetate or (b) reacting 2-amidophenoxyacetic acid with tetrahydrofurfuryl alcohol or a functional derivative thereof. The compound of the invention has pharmaceutical activity (see Division A5). Tetrahydrofurfuryl chloroacetate is prepared by reacting tetrahydrofurfuryl alcohol and chloroacetyl chloride in anhydrous chloroform.ALSO:Compositions having analgesic, antiphlogistic, anaesthetic and rubefacient activity comprise tetrahydrofurfuryl 2-amidophenoxyacetate in combination with a pharmaceutical carrier and may be in forms suitable for oral, topical, parenteral or rectal administration, for example as lozenges, powders, ointments, lotions, creams, sticks, spray-solutions, aerosols, solutions, emulsions or suppositories. Other anti-inflammatory agents may be present, for example salicylic acid derivatives, nicotinic esters or essential oils.
GB2587562A 1962-07-05 1962-07-05 Pharmaceutically active amide Expired GB983122A (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
GB2587562A GB983122A (en) 1962-07-05 1962-07-05 Pharmaceutically active amide
BR15043863A BR6350438D0 (en) 1962-07-05 1963-07-03 PROCESS FOR THE PREPARATION OF 2-STARCH-PHENOXY-ACETATE OF TETRA-HYDROFURFURYL
ES289620A ES289620A1 (en) 1962-07-05 1963-07-04 A procedure for the preparation of 2-amido-phenoxyacetate of tetrahidrofurfurilo (Machine-translation by Google Translate, not legally binding)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2587562A GB983122A (en) 1962-07-05 1962-07-05 Pharmaceutically active amide

Publications (1)

Publication Number Publication Date
GB983122A true GB983122A (en) 1965-02-10

Family

ID=10234798

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2587562A Expired GB983122A (en) 1962-07-05 1962-07-05 Pharmaceutically active amide

Country Status (3)

Country Link
BR (1) BR6350438D0 (en)
ES (1) ES289620A1 (en)
GB (1) GB983122A (en)

Also Published As

Publication number Publication date
BR6350438D0 (en) 1973-08-02
ES289620A1 (en) 1963-10-16

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