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GB981242A - Vaccines containing rare earth salts - Google Patents

Vaccines containing rare earth salts

Info

Publication number
GB981242A
GB981242A GB3762061A GB3762061A GB981242A GB 981242 A GB981242 A GB 981242A GB 3762061 A GB3762061 A GB 3762061A GB 3762061 A GB3762061 A GB 3762061A GB 981242 A GB981242 A GB 981242A
Authority
GB
United Kingdom
Prior art keywords
rare earth
vaccine
earth cation
vaccines
braxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3762061A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Priority to GB3762061A priority Critical patent/GB981242A/en
Publication of GB981242A publication Critical patent/GB981242A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

The antigenicity of vaccines containing antigenic material of microbial origin is enhanced by mixing with the vaccine a salt containing a rare earth cation associated with an immunologically acceptable anion. A concentration between about 2 g. and about 0.008 g. of the rare earth cation is employed per 100 ml. of vaccine. Preferably, an aqueous solution of a water-soluble salt of the rare earth cation is added to the vaccine, but the vaccine may be added to a water-insoluble salt of the rare earth cation. Lanthanum and cerium salts may be used, particularly the acetate. Vaccines specified are Pulpy kidney, Braxy, Blackleg, Braxy-blackleg-pulpy kidney and a seven valent vaccine for diseases of the sheep. The invention also relates to the treatment of diseases in animals due to pathogenic microbes by the parenteral administration of the above vaccines.
GB3762061A 1961-10-19 1961-10-19 Vaccines containing rare earth salts Expired GB981242A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB3762061A GB981242A (en) 1961-10-19 1961-10-19 Vaccines containing rare earth salts

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3762061A GB981242A (en) 1961-10-19 1961-10-19 Vaccines containing rare earth salts

Publications (1)

Publication Number Publication Date
GB981242A true GB981242A (en) 1965-01-20

Family

ID=10397783

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3762061A Expired GB981242A (en) 1961-10-19 1961-10-19 Vaccines containing rare earth salts

Country Status (1)

Country Link
GB (1) GB981242A (en)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3522347A (en) * 1968-01-25 1970-07-28 American Cyanamid Co Toxoid compositions
EP0232717A2 (en) * 1986-01-10 1987-08-19 Shiosaka Sadao Antibody specific to low-molecular weight substance and method of producing the same by using colloidal metal particles as carrier
US5656298A (en) * 1992-09-25 1997-08-12 Dynagen, Inc. Immunobooster for delayed release of immunogen
US6528051B2 (en) 1997-11-10 2003-03-04 Cytimmune Sciences, Inc. Methods and compositions for enhancing immune response
US7229841B2 (en) 2001-04-30 2007-06-12 Cytimmune Sciences, Inc. Colloidal metal compositions and methods
US7951614B2 (en) 2003-12-02 2011-05-31 Cytimmune Sciences, Inc. Methods and compositions for the production of monoclonal antibodies
US7960145B2 (en) 2007-11-08 2011-06-14 Cytimmune Sciences, Inc. Compositions and methods for generating antibodies
US8137989B2 (en) 1994-03-18 2012-03-20 Cytimmune Sciences, Inc. Method for delivering a cytokine using a colloidal metal

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3522347A (en) * 1968-01-25 1970-07-28 American Cyanamid Co Toxoid compositions
EP0232717A2 (en) * 1986-01-10 1987-08-19 Shiosaka Sadao Antibody specific to low-molecular weight substance and method of producing the same by using colloidal metal particles as carrier
EP0232717A3 (en) * 1986-01-10 1989-02-15 Shiosaka Sadao Antibody specific to low-molecular weight substance and method of producing the same by using colloidal metal particles as carrier
US5112606A (en) * 1986-01-10 1992-05-12 Sadao Shiosaka Method of producing antibodies using colloidal metal as carrier
US5656298A (en) * 1992-09-25 1997-08-12 Dynagen, Inc. Immunobooster for delayed release of immunogen
US8137989B2 (en) 1994-03-18 2012-03-20 Cytimmune Sciences, Inc. Method for delivering a cytokine using a colloidal metal
US6528051B2 (en) 1997-11-10 2003-03-04 Cytimmune Sciences, Inc. Methods and compositions for enhancing immune response
US7387900B2 (en) 1997-11-10 2008-06-17 Cytimmune Sciences, Inc. Colloidal metal compositions and methods
US7790167B2 (en) 1997-11-10 2010-09-07 Cyt Immune Sciences, Inc. Methods and compositions for enhancing immune response and for the production of in vitro Mabs
US7229841B2 (en) 2001-04-30 2007-06-12 Cytimmune Sciences, Inc. Colloidal metal compositions and methods
USRE42524E1 (en) 2001-04-30 2011-07-05 Cytimmune Sciences, Inc. Colloidal metal compositions and methods
US8785202B2 (en) 2001-04-30 2014-07-22 Cytimmune Sciences, Inc. Colloidal metal compositions and methods
US7951614B2 (en) 2003-12-02 2011-05-31 Cytimmune Sciences, Inc. Methods and compositions for the production of monoclonal antibodies
US7960145B2 (en) 2007-11-08 2011-06-14 Cytimmune Sciences, Inc. Compositions and methods for generating antibodies
US8486663B2 (en) 2007-11-08 2013-07-16 Cytlmmune Sciences, Inc. Compositions and methods for generating antibodies

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