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Expired
Application number
GB4395560A
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Syntex SA
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Syntex SA
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Publication of GB971049ApublicationCriticalpatent/GB971049A/en
C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07J—STEROIDS
C07J75/00—Processes for the preparation of steroids in general
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Chemical & Material Sciences
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Organic Chemistry
(AREA)
Health & Medical Sciences
(AREA)
General Health & Medical Sciences
(AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof
(AREA)
Abstract
The invention comprises compounds of the general formula:-<FORM:0971049/C1/1> (in which R is hydrogen or methyl, R1 is hydrogen or a hydrocarbon carboxylic acyl group of less than 12 carbon atoms, R2 is hydrogen or a lower alkyl radical having from 1 to 6 carbon atoms, and R3 is hydrogen, lower alkyl, aralkyl containing up to 12 carbon atoms or a hydrocarbon carboxylic acyl group of less than 12 carbon atoms) together with a process for their preparation that includes the step of hydrogenating a compound of the general formula:- <FORM:0971049/C1/2> in the presence of a hydrogenation catalyst and in an inert solvent at a pH between 6.9 and 7.2. The optional steps of etherification and esterification may be carried out prior to or subsequent to the hydrogenation process. The invention is illustrated by sixteen detailed examples. Specification 874,396 is referred to. Reference has been directed by the Comptroller to Specification 854,409.
GB4395560A1960-01-061960-12-21Novel cyclopentanophenanthrene compounds and a process for the production thereof
ExpiredGB971049A
(en)