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GB960302A - Alkenylamines - Google Patents

Alkenylamines

Info

Publication number
GB960302A
GB960302A GB39471/62A GB3947162A GB960302A GB 960302 A GB960302 A GB 960302A GB 39471/62 A GB39471/62 A GB 39471/62A GB 3947162 A GB3947162 A GB 3947162A GB 960302 A GB960302 A GB 960302A
Authority
GB
United Kingdom
Prior art keywords
alkenylamines
diphenylpropenylamines
diphenylpropenyl
propylamine
alkylating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB39471/62A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BK Giulini Chemie GmbH
Original Assignee
Giulini Gebrueder GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Giulini Gebrueder GmbH filed Critical Giulini Gebrueder GmbH
Publication of GB960302A publication Critical patent/GB960302A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C07C215/30—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings containing hydroxy groups and carbon atoms of six-membered aromatic rings bound to the same carbon atom of the carbon skeleton
    • C07C215/32—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings containing hydroxy groups and carbon atoms of six-membered aromatic rings bound to the same carbon atom of the carbon skeleton containing hydroxy groups and carbon atoms of two six-membered aromatic rings bound to the same carbon atom of the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The invention comprises diphenylpropenylamines of the formula <FORM:0960302/C1/1> wherein R1 and R2 are alkyl or cycloalkyl groups, e.g. CH3, C3H7, C5H11, and non toxic acid-addition salts thereof, and their preparation either by treating a corresponding 3-hydroxy-3,3-diphenyl-propylamine with a dehydrating agent or by alkylating 2-ethyl-3,3-diphenylpropenyl-(2)-amine by Leuckart reaction with a carbonyl compound in the presence of formic acid.
GB39471/62A 1961-10-19 1962-10-18 Alkenylamines Expired GB960302A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEG33376A DE1149002B (en) 1961-10-19 1961-10-19 Process for the preparation of hypertensive salts of N, N-dialkyl-2-ethyl-3, 3-diphenyl-propen- (2) -yl-amines

Publications (1)

Publication Number Publication Date
GB960302A true GB960302A (en) 1964-06-10

Family

ID=7124680

Family Applications (1)

Application Number Title Priority Date Filing Date
GB39471/62A Expired GB960302A (en) 1961-10-19 1962-10-18 Alkenylamines

Country Status (4)

Country Link
US (1) US3489760A (en)
DE (1) DE1149002B (en)
FR (1) FR1395525A (en)
GB (1) GB960302A (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1135926A (en) * 1966-02-24 1968-12-11 Geistlich Soehne Ag Pharmaceutical compositions containing bisphenyl-alkenylamine derivatives
DE19805370A1 (en) * 1997-03-14 1998-09-17 Gruenenthal Gmbh New aromatic amino compounds

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA525752A (en) * 1956-06-05 V. Petersen Poul Antispasmodic unsaturated tertiary amines
GB624117A (en) * 1946-12-07 1949-05-27 Wellcome Found Improvements in and relating to the preparation of substituted allylamines and propylamines
GB627139A (en) * 1947-05-28 1949-07-29 Wellcome Found Improvements in and relating to the preparation of quaternary ammonium salts of substituted propanolamines, allylamines and propylamines
CH294173A (en) * 1950-10-09 1953-10-31 Sharp & Dohme Inc Process for the preparation of a quaternary ammonium compound.
DE1051281B (en) * 1955-07-05 1959-02-26 Bayer Ag Process for the preparation of derivatives of 1-aryl-3-aminopropan-1-ols
NL224562A (en) * 1957-02-05
GB993525A (en) * 1961-05-19 1965-05-26 Smith Kline French Lab Substituted propanolamines and process for preparing the same

Also Published As

Publication number Publication date
US3489760A (en) 1970-01-13
FR1395525A (en) 1965-04-16
DE1149002B (en) 1963-05-22

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