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GB933195A - N-ú­-toluenesulfonyl-n-(ª -methyl sulfinylethyl)-urea and a process for the production thereof - Google Patents

N-ú­-toluenesulfonyl-n-(ª -methyl sulfinylethyl)-urea and a process for the production thereof

Info

Publication number
GB933195A
GB933195A GB24562/61A GB2456261A GB933195A GB 933195 A GB933195 A GB 933195A GB 24562/61 A GB24562/61 A GB 24562/61A GB 2456261 A GB2456261 A GB 2456261A GB 933195 A GB933195 A GB 933195A
Authority
GB
United Kingdom
Prior art keywords
urea
toluenesulphonyl
reacting
sulphonyl
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB24562/61A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cilag Chemie Ltd
Original Assignee
Cilag Chemie Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH808760A external-priority patent/CH376897A/en
Application filed by Cilag Chemie Ltd filed Critical Cilag Chemie Ltd
Publication of GB933195A publication Critical patent/GB933195A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/50Compounds containing any of the groups, X being a hetero atom, Y being any atom
    • C07C311/52Y being a hetero atom
    • C07C311/54Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The invention comprises N-p-toluenesulphonyl-N1-(b -methylsulphinylethyl)-urea of the formula CH3,C6H4,SO2,NH,CO,NH ,C2H4,SO,CH3 and its preparation by reacting p-toluenesulphonyl urea with b -methylsulphinylethylamine hydrochloride in a molecular ratio of 1 : 1,1, in dioxane or dimethylformamide, at a temperature of approximately 100 DEG C. The above compound may also be made by other standard methods for the preparation of sulphonyl ureas, by reacting a p-toluenesulphonyl compound CH3,C6H4,SO2X with a compound Y,C2H4,Z1,CH3 wherein Z1 = S or SO (the former being subsequently oxidized to the latter) and X and Y represent radicals capable of forming the urea bridge, e.g. -NCO, -NH2; -NH,CO-Hal, -NH2; -NHCOOAr, -NH2; -NHCONH2, -NH2; -NHCONH Acyl, -NH2; -NHCONH,NO2, -NH2; -NHCONHAr, -NH2; -CON3, -NH2 and -CO,NH,Hal, -NH2; or by reacting a sulphonyl halide (X = halogen) with an isourea ether -NH,C(OR): NH and hydrolysing the resulting sulphonyl isourea ether. Specification 824,218 is referred to.
GB24562/61A 1960-07-15 1961-07-06 N-ú­-toluenesulfonyl-n-(ª -methyl sulfinylethyl)-urea and a process for the production thereof Expired GB933195A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH808760A CH376897A (en) 1960-07-15 1960-07-15 Process for the preparation of a new sulfonylurea
CH226161 1961-02-24

Publications (1)

Publication Number Publication Date
GB933195A true GB933195A (en) 1963-08-08

Family

ID=25689944

Family Applications (1)

Application Number Title Priority Date Filing Date
GB24562/61A Expired GB933195A (en) 1960-07-15 1961-07-06 N-ú­-toluenesulfonyl-n-(ª -methyl sulfinylethyl)-urea and a process for the production thereof

Country Status (2)

Country Link
FR (1) FR1482M (en)
GB (1) GB933195A (en)

Also Published As

Publication number Publication date
FR1482M (en) 1962-09-10

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