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GB926335A - Improvements in azocines - Google Patents

Improvements in azocines

Info

Publication number
GB926335A
GB926335A GB39172/59A GB3917259A GB926335A GB 926335 A GB926335 A GB 926335A GB 39172/59 A GB39172/59 A GB 39172/59A GB 3917259 A GB3917259 A GB 3917259A GB 926335 A GB926335 A GB 926335A
Authority
GB
United Kingdom
Prior art keywords
aminophenylpropane
cyclisation
gives
tetrahydroazocine
aminophenylpropan
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB39172/59A
Inventor
Robert Michel Jacob
Jean Clement Louis Fouche
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc SA
Original Assignee
Rhone Poulenc SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to NL107832D priority Critical patent/NL107832C/xx
Application filed by Rhone Poulenc SA filed Critical Rhone Poulenc SA
Priority to GB39172/59A priority patent/GB926335A/en
Priority to FR838093A priority patent/FR1327721A/en
Priority to CH1202060A priority patent/CH387637A/en
Publication of GB926335A publication Critical patent/GB926335A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/22Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The invention comprises dibenz[bg]tetrahydroazocine, which can be obtained by the cyclisation of 1,3-di-o-aminophenylpropane or one of its salts, e.g. the diphosphate. 2,2-dinitro-chalcone in methanol is reacted with potassium borohydride to give 1,3-di-o-nitrophenyl-3-hydroxyprop-1-ene, which is hydrogenated to 1,3-di-o-aminophenylpropan-1-ol. Treatment of the alcohol with acetic anhydride gives the acetyl derivative, from which 1,3-di-o-acetylaminophenyl-1-chloropropane is obtained with thionyl chloride. Hydrogenation gives 1,3-di-o-acetylaminophenylpropane from which 1,3-di-o-aminophenylpropane is obtained by hydrolysis. According to the Provisional Specification the azocine can be obtained by cyclisation of a compound in which one of the ortho groups is halogen.
GB39172/59A 1959-11-18 1959-11-18 Improvements in azocines Expired GB926335A (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
NL107832D NL107832C (en) 1959-11-18
GB39172/59A GB926335A (en) 1959-11-18 1959-11-18 Improvements in azocines
FR838093A FR1327721A (en) 1959-11-18 1960-09-08 Dibenz [b, g] tetrahydroazocine and its preparation
CH1202060A CH387637A (en) 1959-11-18 1960-10-27 Process for preparing dibenz (b, g) tetrahydroazocine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB39172/59A GB926335A (en) 1959-11-18 1959-11-18 Improvements in azocines

Publications (1)

Publication Number Publication Date
GB926335A true GB926335A (en) 1963-05-15

Family

ID=35613821

Family Applications (1)

Application Number Title Priority Date Filing Date
GB39172/59A Expired GB926335A (en) 1959-11-18 1959-11-18 Improvements in azocines

Country Status (4)

Country Link
CH (1) CH387637A (en)
FR (1) FR1327721A (en)
GB (1) GB926335A (en)
NL (1) NL107832C (en)

Also Published As

Publication number Publication date
NL107832C (en)
FR1327721A (en) 1963-05-24
CH387637A (en) 1965-02-15

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