GB926335A - Improvements in azocines - Google Patents
Improvements in azocinesInfo
- Publication number
- GB926335A GB926335A GB39172/59A GB3917259A GB926335A GB 926335 A GB926335 A GB 926335A GB 39172/59 A GB39172/59 A GB 39172/59A GB 3917259 A GB3917259 A GB 3917259A GB 926335 A GB926335 A GB 926335A
- Authority
- GB
- United Kingdom
- Prior art keywords
- aminophenylpropane
- cyclisation
- gives
- tetrahydroazocine
- aminophenylpropan
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The invention comprises dibenz[bg]tetrahydroazocine, which can be obtained by the cyclisation of 1,3-di-o-aminophenylpropane or one of its salts, e.g. the diphosphate. 2,2-dinitro-chalcone in methanol is reacted with potassium borohydride to give 1,3-di-o-nitrophenyl-3-hydroxyprop-1-ene, which is hydrogenated to 1,3-di-o-aminophenylpropan-1-ol. Treatment of the alcohol with acetic anhydride gives the acetyl derivative, from which 1,3-di-o-acetylaminophenyl-1-chloropropane is obtained with thionyl chloride. Hydrogenation gives 1,3-di-o-acetylaminophenylpropane from which 1,3-di-o-aminophenylpropane is obtained by hydrolysis. According to the Provisional Specification the azocine can be obtained by cyclisation of a compound in which one of the ortho groups is halogen.
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL107832D NL107832C (en) | 1959-11-18 | ||
GB39172/59A GB926335A (en) | 1959-11-18 | 1959-11-18 | Improvements in azocines |
FR838093A FR1327721A (en) | 1959-11-18 | 1960-09-08 | Dibenz [b, g] tetrahydroazocine and its preparation |
CH1202060A CH387637A (en) | 1959-11-18 | 1960-10-27 | Process for preparing dibenz (b, g) tetrahydroazocine |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB39172/59A GB926335A (en) | 1959-11-18 | 1959-11-18 | Improvements in azocines |
Publications (1)
Publication Number | Publication Date |
---|---|
GB926335A true GB926335A (en) | 1963-05-15 |
Family
ID=35613821
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB39172/59A Expired GB926335A (en) | 1959-11-18 | 1959-11-18 | Improvements in azocines |
Country Status (4)
Country | Link |
---|---|
CH (1) | CH387637A (en) |
FR (1) | FR1327721A (en) |
GB (1) | GB926335A (en) |
NL (1) | NL107832C (en) |
-
0
- NL NL107832D patent/NL107832C/xx active
-
1959
- 1959-11-18 GB GB39172/59A patent/GB926335A/en not_active Expired
-
1960
- 1960-09-08 FR FR838093A patent/FR1327721A/en not_active Expired
- 1960-10-27 CH CH1202060A patent/CH387637A/en unknown
Also Published As
Publication number | Publication date |
---|---|
NL107832C (en) | |
FR1327721A (en) | 1963-05-24 |
CH387637A (en) | 1965-02-15 |
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