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GB925567A - Improvements in and relating to lysine nicotinate and its therapeutic applications - Google Patents

Improvements in and relating to lysine nicotinate and its therapeutic applications

Info

Publication number
GB925567A
GB925567A GB27214/61A GB2721461A GB925567A GB 925567 A GB925567 A GB 925567A GB 27214/61 A GB27214/61 A GB 27214/61A GB 2721461 A GB2721461 A GB 2721461A GB 925567 A GB925567 A GB 925567A
Authority
GB
United Kingdom
Prior art keywords
relating
therapeutic applications
nicotinate
lysine nicotinate
lysine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB27214/61A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Adisseo France SAS
Original Assignee
AEC Societe de Chimie Organique and Biologique SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AEC Societe de Chimie Organique and Biologique SA filed Critical AEC Societe de Chimie Organique and Biologique SA
Publication of GB925567A publication Critical patent/GB925567A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Preliminary Treatment Of Fibers (AREA)

Abstract

The invention comprises lysine nicotinate having the formula: <FORM:0925567/IV(a)/1> and a therapeutic composition thereof having hypocholesterolemia inducing properties and vaso-dilating properties. Such compositions are administered orally as tablets, by injection or in the form of suppositories.
GB27214/61A 1960-07-29 1961-07-27 Improvements in and relating to lysine nicotinate and its therapeutic applications Expired GB925567A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR834519A FR84M (en) 1960-07-29 1960-07-29

Publications (1)

Publication Number Publication Date
GB925567A true GB925567A (en) 1963-05-08

Family

ID=8736586

Family Applications (1)

Application Number Title Priority Date Filing Date
GB27214/61A Expired GB925567A (en) 1960-07-29 1961-07-27 Improvements in and relating to lysine nicotinate and its therapeutic applications

Country Status (5)

Country Link
BE (1) BE606636A (en)
CH (1) CH394199A (en)
ES (1) ES269440A1 (en)
FR (1) FR84M (en)
GB (1) GB925567A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3973027A (en) * 1974-03-07 1976-08-03 Roemmers Sociedad Anonima Industrial, Comercial Y Financiera Analgesic method containing Lysine 2-(2-methyl-3-chloro-anilino)-3-nicotinate
US4332792A (en) * 1980-07-14 1982-06-01 Zoecon Corporation Insect attractant
WO1991007188A1 (en) * 1989-11-22 1991-05-30 Adrian Barbul Method for reducing blood cholesterol using arginine
JP2021525279A (en) * 2018-05-22 2021-09-24 ジャンプスタート ファーティリティ ピーティーワイ リミテッド Amino acid salt of nicotinic acid riboside as an anti-aging agent

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3973027A (en) * 1974-03-07 1976-08-03 Roemmers Sociedad Anonima Industrial, Comercial Y Financiera Analgesic method containing Lysine 2-(2-methyl-3-chloro-anilino)-3-nicotinate
US4332792A (en) * 1980-07-14 1982-06-01 Zoecon Corporation Insect attractant
WO1991007188A1 (en) * 1989-11-22 1991-05-30 Adrian Barbul Method for reducing blood cholesterol using arginine
US5157022A (en) * 1989-11-22 1992-10-20 Adrian Barbul Method for reducing blood cholesterol using arginine
JP2021525279A (en) * 2018-05-22 2021-09-24 ジャンプスタート ファーティリティ ピーティーワイ リミテッド Amino acid salt of nicotinic acid riboside as an anti-aging agent

Also Published As

Publication number Publication date
CH394199A (en) 1965-06-30
FR84M (en) 1961-01-09
BE606636A (en) 1961-11-16
ES269440A1 (en) 1962-01-01

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