GB9218810D0 - Antiviral pyrimidine nucleosides - Google Patents
Antiviral pyrimidine nucleosidesInfo
- Publication number
- GB9218810D0 GB9218810D0 GB929218810A GB9218810A GB9218810D0 GB 9218810 D0 GB9218810 D0 GB 9218810D0 GB 929218810 A GB929218810 A GB 929218810A GB 9218810 A GB9218810 A GB 9218810A GB 9218810 D0 GB9218810 D0 GB 9218810D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- pyrimidine nucleosides
- antiviral pyrimidine
- antiviral
- nucleosides
- pyrimidine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000000840 anti-viral effect Effects 0.000 title 1
- 239000002718 pyrimidine nucleoside Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB929218810A GB9218810D0 (en) | 1992-09-04 | 1992-09-04 | Antiviral pyrimidine nucleosides |
| PCT/GB1993/001858 WO1994005687A1 (en) | 1992-09-04 | 1993-09-03 | Antiviral pyrimidine nucleosides |
| CA002143834A CA2143834A1 (en) | 1992-09-04 | 1993-09-03 | Antiviral pyrimidine nucleosides |
| JP6506988A JPH08504753A (en) | 1992-09-04 | 1993-09-03 | Antiviral virimidine nucleoside |
| AU49733/93A AU4973393A (en) | 1992-09-04 | 1993-09-03 | Antiviral pyrimidine nucleosides |
| EP94908867A EP0658166A1 (en) | 1992-09-04 | 1993-09-03 | Antiviral pyrimidine nucleosides |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB929218810A GB9218810D0 (en) | 1992-09-04 | 1992-09-04 | Antiviral pyrimidine nucleosides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB9218810D0 true GB9218810D0 (en) | 1992-10-21 |
Family
ID=10721446
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB929218810A Pending GB9218810D0 (en) | 1992-09-04 | 1992-09-04 | Antiviral pyrimidine nucleosides |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0658166A1 (en) |
| JP (1) | JPH08504753A (en) |
| AU (1) | AU4973393A (en) |
| CA (1) | CA2143834A1 (en) |
| GB (1) | GB9218810D0 (en) |
| WO (1) | WO1994005687A1 (en) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19544768C1 (en) * | 1995-11-30 | 1997-07-10 | Rentschler Arzneimittel | Use of a combination of pentoxifylline with type I interferons to treat multiple sclerosis |
| US20030008841A1 (en) * | 2000-08-30 | 2003-01-09 | Rene Devos | Anti-HCV nucleoside derivatives |
| US8481712B2 (en) | 2001-01-22 | 2013-07-09 | Merck Sharp & Dohme Corp. | Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase |
| RS50236B (en) * | 2001-01-22 | 2009-07-15 | Merck & Co.Inc., | NUCLEOSIDE DERIVATIVES AS INVESTORS OF RNA-DEPENDENT RNA VIRAL POLYMERASES |
| CA2518234C (en) | 2003-03-03 | 2012-11-13 | Guilford Pharmaceuticals Inc. | Thiolactones |
| KR20060035652A (en) * | 2003-06-30 | 2006-04-26 | 이데닉스 (케이만) 리미티드 | Synthesis of β-L-2-deoxy Nucleoside |
| WO2012142093A2 (en) | 2011-04-13 | 2012-10-18 | Merck Sharp & Dohme Corp. | 2'-cyano substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases |
| EP2696681B1 (en) | 2011-04-13 | 2018-10-03 | Merck Sharp & Dohme Corp. | 2'-substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases |
| EP2697242B1 (en) | 2011-04-13 | 2018-10-03 | Merck Sharp & Dohme Corp. | 2'-azido substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases |
| US9416154B2 (en) | 2011-07-13 | 2016-08-16 | Merck Sharp & Dohme Corp. | 5′-substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases |
| WO2013009737A1 (en) | 2011-07-13 | 2013-01-17 | Merck Sharp & Dohme Corp. | 5'-substituted nucleoside analogs and methods of use thereof for the treatment of viral diseases |
| TW201340971A (en) * | 2012-03-09 | 2013-10-16 | Taiho Pharmaceutical Co Ltd | Dna-damaging agent |
| TW201343663A (en) * | 2012-03-16 | 2013-11-01 | Taiho Pharmaceutical Co Ltd | Novel pyrimidine nucleoside compound |
| TWI637963B (en) | 2012-03-28 | 2018-10-11 | 富士軟片股份有限公司 | Salt of 1-(2-deoxy-2-fluoro-4-thio-β-d-arabinofuranosyl) cytosine technical field |
| RS58568B1 (en) | 2012-08-13 | 2019-05-31 | Fujifilm Corp | Intermediate for synthesis of 1-(2-deoxy-2-fluoro-4-thio-beta-d-arabinofuranosyl) cytosine, intermediate for synthesis of thionucleoside, and methods for producing these intermediates |
| JP6175553B2 (en) * | 2014-02-18 | 2017-08-09 | 富士フイルム株式会社 | Method for producing thiolane skeleton type sugar compound and thiolane skeleton type sugar compound |
| JP6204223B2 (en) | 2014-02-19 | 2017-09-27 | 富士フイルム株式会社 | Method for producing thiopyranose compound, etc. |
| TWI678373B (en) | 2014-10-31 | 2019-12-01 | 日商富士軟片股份有限公司 | Thionucleoside derivative or its salt and pharmaceutical composition |
| KR102198656B1 (en) | 2016-08-31 | 2021-01-05 | 후지필름 가부시키가이샤 | Anti-tumor agent, anti-tumor effect enhancer and anti-tumor kit |
| TW201932119A (en) | 2018-01-29 | 2019-08-16 | 日商富士軟片股份有限公司 | Antitumor agent for biliary cancer and treatment method of biliary cancer |
| WO2022008025A1 (en) * | 2020-07-05 | 2022-01-13 | Since & Technology Development Fund Authority | 2-hydroxyiminopyrimidine nucleosides and derivitives and antiviral uses thereto |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE8802687D0 (en) * | 1988-07-20 | 1988-07-20 | Astra Ab | NUCLEOSIDE DERIVATIVES |
| NZ234534A (en) * | 1989-07-17 | 1994-12-22 | Univ Birmingham | Pyrimidine 4'-thionucleoside derivatives and their preparation; intermediates therefor |
| JP3207852B2 (en) * | 1989-09-15 | 2001-09-10 | サザン リサーチ インスティテュート | 2'-Deoxy-4'-thioribonucleosides as antiviral and anticancer agents |
| IE74701B1 (en) * | 1989-10-04 | 1997-07-30 | Univ Birmingham | Further antiviral pyrimidine nucleosides |
| US5128458A (en) * | 1990-04-20 | 1992-07-07 | Southern Research Institute | 2',3'-dideoxy-4'-thioribonucleosides as antiviral agents |
| SE9003151D0 (en) * | 1990-10-02 | 1990-10-02 | Medivir Ab | NUCLEOSIDE DERIVATIVES |
| FR2668153B1 (en) * | 1990-10-22 | 1995-03-31 | Pasteur Merieux Serums Vacc | NOVEL RIBONUCLEOSIDE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM. |
| IT1246983B (en) * | 1990-11-13 | 1994-12-12 | Consiglio Nazionale Ricerche | L-2'-DESOXYURIDINE AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN IT. |
-
1992
- 1992-09-04 GB GB929218810A patent/GB9218810D0/en active Pending
-
1993
- 1993-09-03 JP JP6506988A patent/JPH08504753A/en active Pending
- 1993-09-03 EP EP94908867A patent/EP0658166A1/en not_active Withdrawn
- 1993-09-03 CA CA002143834A patent/CA2143834A1/en not_active Abandoned
- 1993-09-03 AU AU49733/93A patent/AU4973393A/en not_active Abandoned
- 1993-09-03 WO PCT/GB1993/001858 patent/WO1994005687A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| JPH08504753A (en) | 1996-05-21 |
| AU4973393A (en) | 1994-03-29 |
| WO1994005687A1 (en) | 1994-03-17 |
| EP0658166A1 (en) | 1995-06-21 |
| CA2143834A1 (en) | 1994-03-17 |
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