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GB9218810D0 - Antiviral pyrimidine nucleosides - Google Patents

Antiviral pyrimidine nucleosides

Info

Publication number
GB9218810D0
GB9218810D0 GB929218810A GB9218810A GB9218810D0 GB 9218810 D0 GB9218810 D0 GB 9218810D0 GB 929218810 A GB929218810 A GB 929218810A GB 9218810 A GB9218810 A GB 9218810A GB 9218810 D0 GB9218810 D0 GB 9218810D0
Authority
GB
United Kingdom
Prior art keywords
pyrimidine nucleosides
antiviral pyrimidine
antiviral
nucleosides
pyrimidine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
GB929218810A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Birmingham
Wellcome Foundation Ltd
Original Assignee
University of Birmingham
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Birmingham, Wellcome Foundation Ltd filed Critical University of Birmingham
Priority to GB929218810A priority Critical patent/GB9218810D0/en
Publication of GB9218810D0 publication Critical patent/GB9218810D0/en
Priority to PCT/GB1993/001858 priority patent/WO1994005687A1/en
Priority to CA002143834A priority patent/CA2143834A1/en
Priority to JP6506988A priority patent/JPH08504753A/en
Priority to AU49733/93A priority patent/AU4973393A/en
Priority to EP94908867A priority patent/EP0658166A1/en
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06Pyrimidine radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
GB929218810A 1992-09-04 1992-09-04 Antiviral pyrimidine nucleosides Pending GB9218810D0 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
GB929218810A GB9218810D0 (en) 1992-09-04 1992-09-04 Antiviral pyrimidine nucleosides
PCT/GB1993/001858 WO1994005687A1 (en) 1992-09-04 1993-09-03 Antiviral pyrimidine nucleosides
CA002143834A CA2143834A1 (en) 1992-09-04 1993-09-03 Antiviral pyrimidine nucleosides
JP6506988A JPH08504753A (en) 1992-09-04 1993-09-03 Antiviral virimidine nucleoside
AU49733/93A AU4973393A (en) 1992-09-04 1993-09-03 Antiviral pyrimidine nucleosides
EP94908867A EP0658166A1 (en) 1992-09-04 1993-09-03 Antiviral pyrimidine nucleosides

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929218810A GB9218810D0 (en) 1992-09-04 1992-09-04 Antiviral pyrimidine nucleosides

Publications (1)

Publication Number Publication Date
GB9218810D0 true GB9218810D0 (en) 1992-10-21

Family

ID=10721446

Family Applications (1)

Application Number Title Priority Date Filing Date
GB929218810A Pending GB9218810D0 (en) 1992-09-04 1992-09-04 Antiviral pyrimidine nucleosides

Country Status (6)

Country Link
EP (1) EP0658166A1 (en)
JP (1) JPH08504753A (en)
AU (1) AU4973393A (en)
CA (1) CA2143834A1 (en)
GB (1) GB9218810D0 (en)
WO (1) WO1994005687A1 (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19544768C1 (en) * 1995-11-30 1997-07-10 Rentschler Arzneimittel Use of a combination of pentoxifylline with type I interferons to treat multiple sclerosis
US20030008841A1 (en) * 2000-08-30 2003-01-09 Rene Devos Anti-HCV nucleoside derivatives
US8481712B2 (en) 2001-01-22 2013-07-09 Merck Sharp & Dohme Corp. Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase
RS50236B (en) * 2001-01-22 2009-07-15 Merck & Co.Inc., NUCLEOSIDE DERIVATIVES AS INVESTORS OF RNA-DEPENDENT RNA VIRAL POLYMERASES
CA2518234C (en) 2003-03-03 2012-11-13 Guilford Pharmaceuticals Inc. Thiolactones
KR20060035652A (en) * 2003-06-30 2006-04-26 이데닉스 (케이만) 리미티드 Synthesis of β-L-2-deoxy Nucleoside
WO2012142093A2 (en) 2011-04-13 2012-10-18 Merck Sharp & Dohme Corp. 2'-cyano substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases
EP2696681B1 (en) 2011-04-13 2018-10-03 Merck Sharp & Dohme Corp. 2'-substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases
EP2697242B1 (en) 2011-04-13 2018-10-03 Merck Sharp & Dohme Corp. 2'-azido substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases
US9416154B2 (en) 2011-07-13 2016-08-16 Merck Sharp & Dohme Corp. 5′-substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases
WO2013009737A1 (en) 2011-07-13 2013-01-17 Merck Sharp & Dohme Corp. 5'-substituted nucleoside analogs and methods of use thereof for the treatment of viral diseases
TW201340971A (en) * 2012-03-09 2013-10-16 Taiho Pharmaceutical Co Ltd Dna-damaging agent
TW201343663A (en) * 2012-03-16 2013-11-01 Taiho Pharmaceutical Co Ltd Novel pyrimidine nucleoside compound
TWI637963B (en) 2012-03-28 2018-10-11 富士軟片股份有限公司 Salt of 1-(2-deoxy-2-fluoro-4-thio-β-d-arabinofuranosyl) cytosine technical field
RS58568B1 (en) 2012-08-13 2019-05-31 Fujifilm Corp Intermediate for synthesis of 1-(2-deoxy-2-fluoro-4-thio-beta-d-arabinofuranosyl) cytosine, intermediate for synthesis of thionucleoside, and methods for producing these intermediates
JP6175553B2 (en) * 2014-02-18 2017-08-09 富士フイルム株式会社 Method for producing thiolane skeleton type sugar compound and thiolane skeleton type sugar compound
JP6204223B2 (en) 2014-02-19 2017-09-27 富士フイルム株式会社 Method for producing thiopyranose compound, etc.
TWI678373B (en) 2014-10-31 2019-12-01 日商富士軟片股份有限公司 Thionucleoside derivative or its salt and pharmaceutical composition
KR102198656B1 (en) 2016-08-31 2021-01-05 후지필름 가부시키가이샤 Anti-tumor agent, anti-tumor effect enhancer and anti-tumor kit
TW201932119A (en) 2018-01-29 2019-08-16 日商富士軟片股份有限公司 Antitumor agent for biliary cancer and treatment method of biliary cancer
WO2022008025A1 (en) * 2020-07-05 2022-01-13 Since & Technology Development Fund Authority 2-hydroxyiminopyrimidine nucleosides and derivitives and antiviral uses thereto

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8802687D0 (en) * 1988-07-20 1988-07-20 Astra Ab NUCLEOSIDE DERIVATIVES
NZ234534A (en) * 1989-07-17 1994-12-22 Univ Birmingham Pyrimidine 4'-thionucleoside derivatives and their preparation; intermediates therefor
JP3207852B2 (en) * 1989-09-15 2001-09-10 サザン リサーチ インスティテュート 2'-Deoxy-4'-thioribonucleosides as antiviral and anticancer agents
IE74701B1 (en) * 1989-10-04 1997-07-30 Univ Birmingham Further antiviral pyrimidine nucleosides
US5128458A (en) * 1990-04-20 1992-07-07 Southern Research Institute 2',3'-dideoxy-4'-thioribonucleosides as antiviral agents
SE9003151D0 (en) * 1990-10-02 1990-10-02 Medivir Ab NUCLEOSIDE DERIVATIVES
FR2668153B1 (en) * 1990-10-22 1995-03-31 Pasteur Merieux Serums Vacc NOVEL RIBONUCLEOSIDE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM.
IT1246983B (en) * 1990-11-13 1994-12-12 Consiglio Nazionale Ricerche L-2'-DESOXYURIDINE AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN IT.

Also Published As

Publication number Publication date
JPH08504753A (en) 1996-05-21
AU4973393A (en) 1994-03-29
WO1994005687A1 (en) 1994-03-17
EP0658166A1 (en) 1995-06-21
CA2143834A1 (en) 1994-03-17

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